Endometrium Kanseri Hastalarında 3D Ultrasonografi VOCAL Teknikle Myometriyal İnvazyon Derinliği ve Evre Prediksiyonu: Prospektif Çalışma

Öz

Amaç: Bu çalışmada, endometrioid tip endometrium kanserli vakaların üç boyutlu – transvajinal ultrasonografi ile preoperatif endometrial volüm ölçümlerinin hem intraoperatif frozen sonuçları hem de nihai patoloji sonuçları ile karşılaştırılması hedeflenmiştir. Gereç ve Yöntem: ÇEndometrial biyopsi sonuçları endometrioid tip gelen, operasyon için hospitalize edilen tüm endometrium kanseri hastalarına operasyondan hemen önce GE Voluson E6 ultrasonografi cihazı ile üç boyutlu transvajinal probu kullanılarak ultrasonografi yapıldı. Endometrial volüm ölçümü, uterin total volüm ölçümü VOCAL yöntemi kullanılarak; endometrium kalınlığı ve hastalıksız myometrium volümleri çizim yapılarak cm3 olarak hesaplandı. Volüm ölçümleri, frozen ve nihai patoloji sonuçları prospektif olarak kaydedildi. Bulgular: Çalışmaya toplam 50 hasta dâhil edildi. Myometerium invazyonunun %50’den az ya da çok olması ile, üç boyutlu – transvajinal ultrasonografi ile yapılan endometrium, myometrium ve uterus volüm ölçümleri arasında istatistiksel anlamlı fark saptanmamıştır (sırasıyla p=0,3, p=0,3, p=0,6). Endometrium volümünün uterus volümüne oranı değerlendirildiğinde yine myometrial invazyon %50 altında ve üzerinde olan gruplarda istatistiksel anlamlı fark saptanmamıştır (p=0,21). Sonuç: Üç boyutlu – transvajinal ultrasonografi uterusun üç boyutlu volüm ölçümüne olanak sağladığından, myometrial infiltrasyon prediksiyonunda umut vaadedici olsa da, alışmamızın sonucu da göstermiştir ki halen araştırılması gereken bir tekniktir. Endometrial kanser invazyonu açısından kullanılabilirliğini ölçebilmek adına daha çok çalışmaya ihtiyaç vardır.

Anahtar Kelimeler

• endometerium kanseri
• prognoz
• prediktivite
• ultasonografi
• Üç boyutlu ultrasonografi

Etik Beyan

Çalışmaya başlanmadan önce etik kurul onayı alınmıştır.

Prediction of Myometrial Invasion Depth and Staging in Endometrial Cancer Patients with Three-Dimensional Ultrasonography Using VOCAL Technique: A Prospective Study

Öz

Objective: In this study, the aim was to compare preoperative endometrial volume measurements using three-dimensional transvaginal ultrasonography in cases of endometrioid type endometrial cancer with both intraoperative frozen results and final pathology results. Material and Method: Ultrasonography was performed using a GE Voluson E6 ultrasound device with a threedimensional transvaginal probe immediately before surgery for all endometrial cancer patients who had endometrial biopsy results of the endometrioid type. Endometrial volume measurement was calculated in cm3 using the VOCAL method for uterine total volume measurement, and drawings were made for endometrial thickness and disease-free myometrial volumes. Volume measurements were prospectively recorded along with frozen and final pathology results. Results: A total of 50 patients were included in the study. There was no statistically significant difference between three-dimensional transvaginal ultrasonography measurements of endometrium, myometrium, and uterine volumes when myometrial invasion was less than or greater than 50% (p=0.3, p=0.3, p=0.6, respectively). Similarly, no statistically significant difference was found in the ratio of endometrial volume to uterine volume when evaluating myometrial invasion below and above 50% (p=0.21). Conclusion: While three-dimensional transvaginal ultrasonography offers the possibility of three-dimensional volume measurement of the uterus and holds promise for predicting myometrial infiltration, our study has shown that it is still a technique that requires further investigation. More research is needed to assess its usability in the context of endometrial cancer invasion.

Anahtar Kelimeler

• endometrial cancer
• predictiveness
• prognosis
• three-dimensional ultrasonography
• ultrasonography

Destekleyen Kurum

none

Etik Beyan

Ethics committee approval was obtained before starting the study.

Teşekkür

none

Kaynakça

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