Cataracts in Cancer Patients: At the Intersection of Oncology and Ophthalmology

Yıl 2026, Cilt: 8 Sayı: 1, 156 - 164, 28.02.2026

Ayşenur Çelik , Sibel Özdoğan

https://doi.org/10.52827/hititmedj.1788020

https://izlik.org/JA27NR62WE

Öz

Purpose: This study investigates the demographics, systemic diseases, and cataract types in cancer patients to improve clinical management.

Methods: A retrospective case-control study was conducted on 330 cataract patients. Among them, half had both cataracts and cancer, while the other half had only cataracts. Demographic data, visual acuity, and systemic disease status were recorded. Cataracts were classified using LOCS III, and statistical analysis was performed with SPSS (p < 0.05).

Results: The study included 165 cancer patients and 165 non-cancer patients with cataracts. Cancer patients were significantly younger (mean age: 61.63 ± 9.57 years) than non-cancer patients (mean age: 70.10 ± 6.09 years) (p = 0.01). Posterior subcapsular cataracts were more prevalent among cancer patients (55%), whereas nuclear cataracts were more frequent in the non-cancer group (37%). Systemic diseases were significantly more prevalent in the control group (76%) compared to cancer patients (60%) (p = 0.0021), with diabetes being the most common comorbidity in both groups.

Conclusion: Cataracts develop at a significantly younger age in cancer patients compared to non-cancer patients, with posterior subcapsular cataracts being more prevalent in the cancer group. Cancer and its treatments may accelerate cataract formation. Regular ophthalmologic evaluations are crucial for the early detection and management of cataracts in cancer patients, ultimately enhancing their quality of life.

Anahtar Kelimeler

Age-Related Cataract , Neoplasms/complications , Posterior Subcapsular Cataract

Etik Beyan

All procedures performed in this study were conducted in accordance with the Helsinki Declaration and relevant ethical guidelines. The study was approved by our Institutional Ethics Committee (Ethics Committee Approval No: 2022-03/61).

Destekleyen Kurum

This study received no funding from any institution or organization.

Teşekkür

The authors would like to express their gratitude to everyone who supported and contributed to this research. No specific individuals or organizations were acknowledged in this study.

Kanser Hastalarında Katarakt: Onkoloji ve Oftalmolojinin Kesişiminde

https://izlik.org/JA27NR62WE

Öz

Amaç: Kanser hastalarında görülen kataraktın klinik özelliklerini incelemek ve kanser dışı katarakt hastaları ile karşılaştırmak.

Gereç ve Yöntem: Retrospektif olgu-kontrol çalışmasına 165’i kanser hastası, 165’i ise kanser tanısı olmayan toplam 330 katarakt hastası dahil edildi. Demografik veriler, görme keskinliği ve sistemik hastalıklar kaydedildi. Kataraktlar LOCS III sınıflamasına göre değerlendirildi. İstatistiksel analizler SPSS programı ile yapıldı (p < 0.05).

Bulgular: Kanser hastalarının yaş ortalaması, kanser dışı hastalardan anlamlı derecede düşüktü (61.63 ± 9.57 vs. 70.10 ± 6.09 yıl, p = 0.01). Kanser grubunda posterior subkapsüler katarakt daha sık görülürken (%55), kontrol grubunda nükleer katarakt daha yaygındı (%37). Sistemik hastalıklar kontrol grubunda daha yüksekti (%76 vs. %60, p = 0.0021). Her iki grupta da en sık komorbidite diyabetti.

Sonuç: Kanser hastalarında kataraktlar daha erken yaşta gelişmekte ve posterior subkapsüler tip daha sık görülmektedir. Kanser ve tedavileri katarakt oluşumunu hızlandırabilir. Kataraktların erken tanı ve tedavisi için düzenli oftalmolojik takip önemlidir ve yaşam kalitesini artırabilir.

Anahtar Kelimeler

Neoplazm/komplikasyon , Posterior subkapsüler katarakt , Yaşa bağlı katarakt.

Etik Beyan

Bu çalışmada yer alan tüm işlemler, Helsinki Deklarasyonu ve ilgili etik kurallar çerçevesinde gerçekleştirilmiştir. Çalışma, kurumumuzun Etik Kurulu tarafından onaylanmıştır (Etik Kurul Onay 2022-03/61).

Destekleyen Kurum

Bu çalışma herhangi bir kurum veya kuruluş tarafından desteklenmemiştir.

Teşekkür

Yazarlar, bu araştırmayı destekleyen ve katkıda bulunan herkese şükranlarını sunmak ister. Bu çalışmada özel olarak herhangi bir kişi veya kurum belirtilmemiştir.

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