Hormone-Negative Retroperitoneal Extra-Adrenal Paraganglioma

Öz

Paragangliomas are rare neuroectodermal tumors originating from the parasympathetic nervous system. In this case report, a case of hormone-negative extra-adrenal paraganglioma located retroperitoneally is presented. A 50-year-old female patient was admitted to our clinic with right flank pain. No pathology including urine and blood catecholamine degradation products was detected in the laboratory examinations of the patient. Computed tomography revealed an iso-hypodense solid lesion of 80x50 mm in size, compressing the inferior vena cava and close to the lower part of the pancreas. Surgery was planned for mass resection. During dissection, a severe hypertensive attack occurred, which was controlled with phentolamine. After removal of the mass, blood pressure remained within normal limits in the intraoperative and postoperative periods. The patient was discharged without complications on the 5th postoperative day.

Anahtar Kelimeler

• Phentolamine
• Hypertensive attack
• Hormone-negative
• Paraganglioma.

Hormon-Negatif Retroperitoneal Ekstra-Adrenal Paraganglioma

Öz

Paragangliomalar, parasempatik sinir sisteminden kaynaklanan nadir görülen nöroektodermal tümörlerdir. Bu olgu sunumunda retroperitoneal yerleşimli bir hormon negatif ekstra-adrenal paraganglioma olgusu sunulmaktadır. 50 yaşında kadın hasta sağ yan ağrısı ile kliniğimize başvurdu. Hastanın laboratuvar incelemelerinde idrar ve kan katekolamin yıkım ürünleri dahil patoloji saptanmadı. Bilgisayarlı tomografide vena kava inferiora bası yapan ve pankreasın alt kısmına yakın 80x50 mm boyutlarında izo-hipodens solid lezyon saptandı. Kitle rezeksiyonu için cerrahi planlandı. Diseksiyonu sırasında fentolamin ile kontrol altına alınan ciddi bir hipertansif atak meydana geldi. Kitlenin çıkarılmasından sonra intraoperatif ve postoperatif dönemde kan basıncı normal sınırlarda seyretti. Hasta postoperatif 5. günde komplikasyonsuz olarak taburcu edildi.

Anahtar Kelimeler

• Fentolamin
• Hipertansif atak
• Hormon-negatif
• Paraganglioma

Kaynakça

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