Removal of Butylated Hydroxyanisole with Enzyme Based Polymerization Using Organo-Clays

Yıl 2008, Cilt: 36 Sayı: 3, 207 - 214, 01.08.2008

Güner Saka Sibel Emir Diltemiz Ayça Atılır Özcan Arzu Ersöz Rıdvan Say

Öz

3,5-di-tert-butyl-4-hydroxytoluene BHT and 2-tert-butyl-4-methoxyphenol BHA are used as antioxidants in food. However, considerable concern has arisen from experiments showing that BHA and BHT are potent enhancers of chemically-induced mutagenesis and carcinogenesis in laboratory animals. This work describes a method for the removalof buytlated hydroxyanisole BHA compound with an enzyme based polymerization onto organo-clay from aqueoussolution. BHA bound organo-clay was prepared from horseradish peroxidase HRP -catalyzed polymerization reaction onto nanolayer of organosimectite. The approach described the enzyme catalyzed oxidation of BHA to quartamin modified smectite

Anahtar Kelimeler

BHA, BHT, smectit, organoclay nanocomposites

Kaynakça

• 1. Anonymous ,. J. Am. Coll. Toxicoll. 3, 83, 1984.
• 2. Ito, N., Fukushima, S. and Tsuda, H., Carcinogenicity and modification of the carcinogenic response by BHA, BHT and other antioxidants, CRC Crit. Rev. Toxicol. 15, 109, 1985.
• 3. Joint FAO/WHO Expert Committee on Food Aditives, WHO Fd. Add. Ser. 21, 3, 1986.
• 4. Ito, N., Fukushima, S., Tamano, S., Hirose, M. and Hagiwara, A., Dose response in butylated hydroxyanisole induction of forestomach carcinogenesis in F344 rats, J. Natn. Cancer. Inst. 77, 1261, 1986.
• 5. Lindenschmidt, R.C., Tryka, A.F., Good, M. E and Witschi, H.P., The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice, Toxicology 38. 151, 1986.
• 6. Olsen, P., Meyer, E., Bille, N. and Würtzen, G. Carcinogenicity study on butylated hydroxytoluene (BHT) in Wistar rats exposed in utero., Food. Chem. Toxicol. 24, 1, 1986.
• 7. Bianchi, L., Colivicchi, M. A., Della Corte, L., Valoti, M., Sgaragli, G. P. and Bechi, P., Measurement of synthetic phenolic antioxidants in human tissues by highperformance liquid chromatography with coulometric electrochemical detection, J. Chromatog. B. 694. 359, 1997.
• 8. Kauffmann, C., Petersen, B.R. and Bjerrum, M.J., Enzymatic removal of phenols from aqueous solutions by Coprinus cinereus peroxidase and hydrogen peroxide, J. Biotechnology 73, 71, 1999.
• 9. Erhan, E., Keskinler, B., Akay, G. and Algur, O.F., Removal of phenol from water by membrane-immobilized enzymes: Part I. Deadend filtration, J. Membrane Science 206, 361, 2002.
• 10. Rao, J.R. and Viraraghavan, T., Biosorption of phenol from an aqueous solution by Aspergillus niger biomass, Bioresource Technology 85, 165, 2002.
• 11. Rengaraj, S., Moon, S-H., Sivabalan, R., Arabindoo, B. and Murugesan, V., Removal of phenol from aqueous solution and resin manufacturing industry wastewater using an agricultural waste: Rubber seed coat, J. Hazardous Materials B 89, 185, 2002.
• 12. Furuya, E.G., Chang, H.T., Miura, Y. and Noll, K.E., A fundamental analysis of the isotherm for the adsorption of phenolic compounds on activated carbon, Sep. Purif. Technol 11(2), 69, 1997.
• 13. Dargaville, T.R., Looney, M.G. and Solomon, H.D., The adsorption of multinuclear phenolic compounds on activated carbon, J. Colloid Interf. Sci. 182, 17, 1996.
• 14. Shu, H.T., Li, D., Scala, A.A. and Ma, Y.H., Adsorption of small organic pollutants from aqueous streams by aluminosilicate, Sep. Purif. Technol 11, 27, 1997.
• 15. Ku ,Y. and Lee, K-C. ,Removal of phenols from aqueous solution by XAD-4 resin, J. Hazardous Materials B 80, 59, 2000.
• 16. Dutta, S., Basu, J.K. and Ghar, R.N., Studies on adsorption of p-nitrophenol on charred sawdust, Separation and Purification Technology 21, 227, 2001.
• 17. Shen, Y-H., Removal of phenol from water by adsorption-flocculation using organobentonit, Water Research 36, 1107, 2002.
• 18. Brüggemann, O., Visnjevski, A., Burch, R. and Patel,P., Selective extraction of antioxidants with molecularly imprinted polymers, Anal. Chim. Acta 504, 81, 2004.
• 19. Dubey, S., Singh, D. And Misra, R.A., Enzymatic synthesis and various properties of poly(catechol), Enzyme and Microbial Technology 23, 432, 1998.
• 20. Zhang, G. and Nicel, J.A., Treatment of aqueous pentachlorophenol by horseradish peroxidase and hydrogen peroxide. Water Research 34 (5), 1629, 2000.
• 21. Masuda, M., Sakurai, A. and Sakakibara, M., Effect of enzyme impurities on phenol removal by the method of polymerization and precipitation catalyzed by Coprinus cinereus peroxidase, Appl. Microbiol. Biotechnol. 57, 494, 2001.
• 22. Caza, N., Bewtra, J.K., Biswas, N.K. and Taylor, E., Removal of phenolic compounds from synthetic wastewater using soybean peroxidase, Water Research 33(13), 3012, 1999.
• 24. Metelitza, D.I., Litvinchuk, A.V. and Savenkova, M.I., Peroxidase-catalyzed co-oxidation of halogen-substituted phenols and 4- aminoantipyrine, J. Mol. Catal. 67, 401, 1991.
• 25. Tabtiang, A., Lumlong, S., Venables, R. A., Liu, J.Z., Song, H.Y., Weng, L.P. and Ji, L.N., Influence of preparation method upon the structure and relaxation characteristics of poly(methyl methacrylate)/clay composites, European Polymer Journal 36, 2259, 2000.
• 26. Say, R., Birlik, E., Denizli, A., Ersöz, A., Removal of heavy metal ions by dithiocarbamate-anchored polymer/organosmectite composites, Applied Clay Science 31, 298, 2006.
• 27. Liu, J.Z., Song, H.Y., Weng, L.P. and Ji, L.N., Increased thermostability and phenol removal efficiency by chemical modified horseradish peroxidase, J. Molecular Catalysis B: Enzymatic 18, 225, 2002.