BibTex RIS Kaynak Göster

Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing

Yıl 2010, Cilt: 38 Sayı: 1, 19 - 25, 01.01.2010

Öz

A series of poly vinyl alcohol PVA /poly vinyl pyrrolidone PVP /poly ethylene glycol PEG hybrid nanofibers were fabricated by an electrospinning method, in order to be used as a potential wound dressing material. The effect of Aloe vera was investigated in terms of solution properties such as viscosity, conductivity, pH and surface tension. The nanofibrous wound dressing materials were characterized by scanning electron microscopy SEM , Fourier transform infrared FT-IR and differential scanning calorimetry DSC . SEM results revealed that the fiber diameters ranged between 200-500 nm and they were linear, homogenous and free of beads. DSC thermograms indicated that the addition of Aloe vera affects the crystal structure and efficiently cross-links the hybrid polymer, forming an amorphous structure with a melting temperature Tm of 219oC at an Aloe vera concentration of 3%. FTIR results clearly resolved the hybrid polymer structure of nanofibers obtained.

Kaynakça

  • Haijun, Y., Xiaoyi, X., Xuesi, C., Tiancheng, L., Peibiao, Z., Xiabin, J., Preparation and antibacterial effects of PVA-PVP hydrogels containing silver nanoparticles, J. Appl. Polym. Sci., 103(1), 125, 2006.
  • Hong, K.H., Preparation and properties of electrospun poly(vinyl alcohol)/silver fiber web as wound dressings, Polym. Eng. Sci., 47(1), 43, 2007.
  • Razzak, M.T., Zainuddin, E., Dewi, S., Lely, H., Taty, S., The characterization of dressing component materials and radiation formation of PVA-PVP hydrogel, Radiat. Phys. Chem., 55,153, 1999.
  • Cassu, S.N., Felisberti, M.I., Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blends: miscibility, microhetero- geneity and free volume change, Polymer, 38, 3907, 1997.
  • Seabra, A.B., Oliveira, M.G., Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blended films for local nitric oxide release, Biomaterials, 25, 3773, 2004.
  • Hilmy, N., Darwis, D., Hardiningsih, L., Poly(N-vinyl- pyrrolidone) hydrogels. 2. Hydrogel composites as wound dressing for tropicalenvironment, Radiat. Phys. Chem., 42(4-6), 911, 1993.
  • Ajji, Z., Othman, I., Rosiak, J.M., Production of hydrogel wound dressings using gamma radiation, Nuc. Inst. Met. Phys. Res. B, 229, 375, 2005.
  • Eshun, K., He, Q., Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries, Crit. Rev. Food Sci. Nutr., 44(2), 91, 2004.
  • Hamman, J.H., Composition and Applications of Aloe vera Leaf Gel, Molecules, 13, 1599, 2008.
  • Tizard, I., Busbee, D., Maxwel, B., Kemp, M.C., Effects of acemannan, a complex carbohydrate, on wound healing in young and aged rats, Wounds: A Compendium of Clin. Res. Pract., 6, 201, 1994.
  • Davis, R.H., Donato, J.J., Hartman, G.M., Haas, R.C., Anti- inflammatory and wound healing activity of a growth substance in Aloe vera, J. Am. Pediatr. Med. Assoc., 84, 77, 1994.
  • Shelton, R.M., Aleo vera. Its chemical and therapeutic properties, Int. J. Dermatol., 30, 679, 1991.
  • Robson, M.C., Heggers, J.P., Hagstrom, W.J.J., Myth, magic, witchcraft, or fact. Aloe vera revisited, Burn Care Rehabil., 3, 157, 1982.
  • Klein, A.D., Penneys, N.S., Aloe vera, J. Am. Acad. Dermatol., 18, 714, 1988.
  • Jensen, J.L., Seeley, J., Gillin, B. Diabetic foot ulcerations. A controlled, randomized comparison of two moist wound healing protocols: Carrasyn Hydrogel Wound dressing and wet-to-moist saline gauze. Adv. Wound Care, 11, 1, 1998.
  • Khil, M.S., Cha, D., Kim, H.Y., Kim, I.S., Bhattarai, N, Electrospun nanofibrous polyurethane membrane as wound dressing, J. Biomed. Mater. Res. Part B: Appl. Biomat., 67B(2), 675, 2003.
  • Shenoy, S.L., Bates, W.D., Frisch, H.L., Wnek, G.E. Role of Chain Entanglements on Fiber Formation during Electrospinning of Polymer Solutions: Good Solvent, Non- specific Polymer-polymer Interaction Limit, Polymer, 46, 3372, 2005.
  • Ramakrishna, S., Fujihara, K., Teo, W.E., Lim, T.C., Ma, Z. An introduction to electrospinning and nanofibers, New Jersey: World Scientific, 1stEd., pp.91-101, 2005.
Yıl 2010, Cilt: 38 Sayı: 1, 19 - 25, 01.01.2010

Öz

Kaynakça

  • Haijun, Y., Xiaoyi, X., Xuesi, C., Tiancheng, L., Peibiao, Z., Xiabin, J., Preparation and antibacterial effects of PVA-PVP hydrogels containing silver nanoparticles, J. Appl. Polym. Sci., 103(1), 125, 2006.
  • Hong, K.H., Preparation and properties of electrospun poly(vinyl alcohol)/silver fiber web as wound dressings, Polym. Eng. Sci., 47(1), 43, 2007.
  • Razzak, M.T., Zainuddin, E., Dewi, S., Lely, H., Taty, S., The characterization of dressing component materials and radiation formation of PVA-PVP hydrogel, Radiat. Phys. Chem., 55,153, 1999.
  • Cassu, S.N., Felisberti, M.I., Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blends: miscibility, microhetero- geneity and free volume change, Polymer, 38, 3907, 1997.
  • Seabra, A.B., Oliveira, M.G., Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blended films for local nitric oxide release, Biomaterials, 25, 3773, 2004.
  • Hilmy, N., Darwis, D., Hardiningsih, L., Poly(N-vinyl- pyrrolidone) hydrogels. 2. Hydrogel composites as wound dressing for tropicalenvironment, Radiat. Phys. Chem., 42(4-6), 911, 1993.
  • Ajji, Z., Othman, I., Rosiak, J.M., Production of hydrogel wound dressings using gamma radiation, Nuc. Inst. Met. Phys. Res. B, 229, 375, 2005.
  • Eshun, K., He, Q., Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries, Crit. Rev. Food Sci. Nutr., 44(2), 91, 2004.
  • Hamman, J.H., Composition and Applications of Aloe vera Leaf Gel, Molecules, 13, 1599, 2008.
  • Tizard, I., Busbee, D., Maxwel, B., Kemp, M.C., Effects of acemannan, a complex carbohydrate, on wound healing in young and aged rats, Wounds: A Compendium of Clin. Res. Pract., 6, 201, 1994.
  • Davis, R.H., Donato, J.J., Hartman, G.M., Haas, R.C., Anti- inflammatory and wound healing activity of a growth substance in Aloe vera, J. Am. Pediatr. Med. Assoc., 84, 77, 1994.
  • Shelton, R.M., Aleo vera. Its chemical and therapeutic properties, Int. J. Dermatol., 30, 679, 1991.
  • Robson, M.C., Heggers, J.P., Hagstrom, W.J.J., Myth, magic, witchcraft, or fact. Aloe vera revisited, Burn Care Rehabil., 3, 157, 1982.
  • Klein, A.D., Penneys, N.S., Aloe vera, J. Am. Acad. Dermatol., 18, 714, 1988.
  • Jensen, J.L., Seeley, J., Gillin, B. Diabetic foot ulcerations. A controlled, randomized comparison of two moist wound healing protocols: Carrasyn Hydrogel Wound dressing and wet-to-moist saline gauze. Adv. Wound Care, 11, 1, 1998.
  • Khil, M.S., Cha, D., Kim, H.Y., Kim, I.S., Bhattarai, N, Electrospun nanofibrous polyurethane membrane as wound dressing, J. Biomed. Mater. Res. Part B: Appl. Biomat., 67B(2), 675, 2003.
  • Shenoy, S.L., Bates, W.D., Frisch, H.L., Wnek, G.E. Role of Chain Entanglements on Fiber Formation during Electrospinning of Polymer Solutions: Good Solvent, Non- specific Polymer-polymer Interaction Limit, Polymer, 46, 3372, 2005.
  • Ramakrishna, S., Fujihara, K., Teo, W.E., Lim, T.C., Ma, Z. An introduction to electrospinning and nanofibers, New Jersey: World Scientific, 1stEd., pp.91-101, 2005.
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Research Article
Yazarlar

İbrahim Uslu Bu kişi benim

Selda Keskin Bu kişi benim

Ali Gül Bu kişi benim

Tutku Ceren Karabulut Bu kişi benim

Mehmet Levent Aksu Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2010
Yayımlandığı Sayı Yıl 2010 Cilt: 38 Sayı: 1

Kaynak Göster

APA Uslu, İ., Keskin, S., Gül, A., Karabulut, T. C., vd. (2010). Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing. Hacettepe Journal of Biology and Chemistry, 38(1), 19-25.
AMA Uslu İ, Keskin S, Gül A, Karabulut TC, Aksu ML. Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing. HJBC. Ocak 2010;38(1):19-25.
Chicago Uslu, İbrahim, Selda Keskin, Ali Gül, Tutku Ceren Karabulut, ve Mehmet Levent Aksu. “Preparation and Properties of Electrospun Poly Vinyl Alcohol Blended Hybrid Polymer With Aloe Vera and HPMC As Wound Dressing”. Hacettepe Journal of Biology and Chemistry 38, sy. 1 (Ocak 2010): 19-25.
EndNote Uslu İ, Keskin S, Gül A, Karabulut TC, Aksu ML (01 Ocak 2010) Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing. Hacettepe Journal of Biology and Chemistry 38 1 19–25.
IEEE İ. Uslu, S. Keskin, A. Gül, T. C. Karabulut, ve M. L. Aksu, “Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing”, HJBC, c. 38, sy. 1, ss. 19–25, 2010.
ISNAD Uslu, İbrahim vd. “Preparation and Properties of Electrospun Poly Vinyl Alcohol Blended Hybrid Polymer With Aloe Vera and HPMC As Wound Dressing”. Hacettepe Journal of Biology and Chemistry 38/1 (Ocak 2010), 19-25.
JAMA Uslu İ, Keskin S, Gül A, Karabulut TC, Aksu ML. Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing. HJBC. 2010;38:19–25.
MLA Uslu, İbrahim vd. “Preparation and Properties of Electrospun Poly Vinyl Alcohol Blended Hybrid Polymer With Aloe Vera and HPMC As Wound Dressing”. Hacettepe Journal of Biology and Chemistry, c. 38, sy. 1, 2010, ss. 19-25.
Vancouver Uslu İ, Keskin S, Gül A, Karabulut TC, Aksu ML. Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing. HJBC. 2010;38(1):19-25.

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