Araştırma Makalesi
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The Effects of Behçet’s Disease on LUTS in Male Patients

Yıl 2021, , 1 - 4, 16.12.2021
https://doi.org/10.29228/HMJ.1

Öz

Abstract
Introduction
In this study, we aimed to evaluate the relationship between Behçet's disease (BD) and lower urinary tract symptoms (LUTS).
Methods
In june 2019 to 2021, 56 male patients who applied to Pamukkale University rheumatology and dermatology outpatient clinics, were diagnosed with Behçet's disease according to the criteria of the international Behçet study group and accepted to participate in the study, were subjected to urological evaluation. The patients were evaluated in terms of Behçet's disease and urological conditions causing LUTS, and the relationship between Behçet's disease and LUTS was examined.
Results
The mean age of the patients was 42.6 years. The mean activity score of BD was 4.6±3.2 and the mean IPSS score was 7.3±7.3. Gender did not have a significant effect on the instantaneous activity score of Behçet's disease. A statistically significant finding was found between Behçet's disease instantaneous activity score and IPSS score, frequency of daytime urination, nocturia and urgency. However, no significant relationship was found with uroflowmetry parameters.
Conclusion
Lower urinary tract involvement in BD without neurological involvement may present with symptom scores before uroflowmetry parameters.

Kaynakça

  • Bang D. Clinical spectrum of Behçet’s disease. J Dermatol. 2001;28:610 3.
  • Behcet H. Uber rezidivierende aphthose, durch ein veirus verusachte geschwure am mund, am auge und an den genitalien. Dermatol Mnatsschr. 1937;(36):1152–7.
  • Bang D, Yoon KH, Chung HG, Choi EH, Lee ES, Lee S. Epidemiological and clinical features of Behçet’s disease in Korea. Yonsei Med J. 1997;38:428–36.
  • Davatchi F. Behçet’s disease. Int J Rheum Dis. 2018;21:2057–8.
  • Davatchi F. Behcet’s disease. Int J Rheum Dis. 2014;17:355–7.
  • Mahr A, Maldini C. Épidémiologie de la maladie de Behçet [Epidemiology of Behçet’s disease] Rev Med Interne. 2014;35:81–9.
  • Zouboulis CC. Epidemiology of Adamantiades-Behçet’s disease. Ann Med Interne (Paris) 1999;150:488–98.
  • International Team for the Revision of the International Criteria for Behçet’s Disease (ITR-ICBD) The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014;28:338–47.
  • Kirkali Z, Yigitbasi O, Sasmaz R. Urological aspects of Behçet’s disease. Br J Urol. 1991;67:638–9.
  • Alizadeh F, Khorrami MH, Izadpanahi MH, Nouri-Mahdavi K, Mohammadi Sichani M. Bladder involvement in Behcet’s disease. Urol J. 2012;9:347–50.
  • Sarica K, Süzer O, Gürler A, Baltaci S, Ozdiler E, Dinçel C. Urological evaluation of Behçet patients and the effect of colchicine on fertility. Eur Urol. 1995;27:39–42.
  • Davatchi F, Akbaran M, Shahram F, Jamshidi A, Gharibdoost F, Chams C. Iran Behcet’s disease dynamic activity measure. Hung Rheumatol Suppl. 1991;32:1340.
  • Krause I, Rosen Y, Kaplan I, et al. Recurrent aphthous stomatitis in Behçet’s disease: clinical features and correlation with systemic disease expression and severity. J Oral Pathol Med. 1999;28:193–6.
  • Suzuki Kurokawa M, Suzuki N. Behcet’s disease. Clin Exp Med. 2004;4:10–20.
  • Cetinel B, Akpinar H, Tüfek I, Uygun N, Solok V, Yazici H. Bladder involvement in Behçet’s syndrome. J Urol. 1999;161:52–6.
  • Cetinel B, Obek C, Solok V, Yaycioglu O, Yazici H. Urologic screening for men with Behçet’s syndrome. Urology. 1998;52:863–5.
  • Erdoğru T, Koçak T, Serdaroğlu P, Kadioğlu A, Tellaloğlu S. Evaluation and therapeutic approaches of voiding and erectile dysfunction in neurological Behçet’s syndrome. J Urol. 1999;162:147–53.
  • Akkoç N. Update on the epidemiology, risk factors and disease outcomes of Behçet’s disease. Best Pract Res Clin Rheumatol. 2018;32:261–70.
  • Davatchi F, Shahram F, Chams-Davatchi C, et al. Behcet’s disease: from East to West. Clin Rheumatol. 2010;29:823–33.

Erkek Hastalarda Behçet Hastalığının AÜSS Üzerine Etkileri

Yıl 2021, , 1 - 4, 16.12.2021
https://doi.org/10.29228/HMJ.1

Öz

Amaç
Bu çalışmada, Behçet hastalığı (BH) ile alt üriner sistem semptomlarının (AÜSS) ilişkisini değerlendirmeyi amaçladık.
Yöntemler:
2019 ve 2021 haziran ayları arasında Pamukkale üniversitesi romatoloji ve dermatoloji polikliniklerine başvuran uluslararası Behçet çalışma grubu kriterlerine göre Behçet hastalığı tanısı almış ve çalışmaya katılmayı kabul eden 56 erkek hasta ürolojik değerlendirmeye tabi tutuldu. Çalışmaya katılan hastaların ürolojik olarak BPH, üriner sistem kanseri, idrar yolu enfeksiyonu, üriner inkontinans cerrahisi geçirmiş olması, nörolojik hastalık veya tutulum varlığı (Parkinson, Multıpl skleroz gibi) ile 18 yaş altında olma dışlama kriteri olarak kabul edildi. Hastalara dermatoloji ve romotaloji kliniklerinde Türkçe validasyonu olan Behçet hastalığı anlık aktivite formu (minimum 0, maksimum 12 puan skorlamasına sahip) ile Behçet hastalığı aktivite durumları sorgulandı ve takip edildiği kliniklerde göz tutulumu, nörolojik tutulumu ve damar tutulumuna göre kategorize edildikten sonra üroloji polikliniğinde uluslararası prostat semptom skorlaması (IPSS) sorgulama formu ile üroflowmetri ve postvoiding rezidü ölçümlerine bakıldı. Demografik ve klinik bilgileri kayıt edildi.
Bulgular:
Hastaların ortalama yaşı 42.6 yıl idi. BH'nın ortalama aktivite skoru 4.6±3.2 ve ortalama IPSS skoru 7.3±7.3 idi. Cinsiyetin Behçet hastalığı anlık aktivite skoru üzerinde anlamlı bir etkisi yoktu. Behçet hastalığı anlık aktivite skoru ile IPSS skoru, gündüz idrara çıkma sıklığı, noktüri ve urgency arasında istatistiksel anlamlı bulgu saptandı. Ancak üroflowmetri parametreleri ile anlamlı bir ilişki saptanmadı.
Sonuç
Sonuç olarak, nörolojik tutulum olmaksızın BH'de alt üriner sistem tutulumu, üroflowmetri parametrelerinden önce semptom skorları ile kendini gösterebilir.

Kaynakça

  • Bang D. Clinical spectrum of Behçet’s disease. J Dermatol. 2001;28:610 3.
  • Behcet H. Uber rezidivierende aphthose, durch ein veirus verusachte geschwure am mund, am auge und an den genitalien. Dermatol Mnatsschr. 1937;(36):1152–7.
  • Bang D, Yoon KH, Chung HG, Choi EH, Lee ES, Lee S. Epidemiological and clinical features of Behçet’s disease in Korea. Yonsei Med J. 1997;38:428–36.
  • Davatchi F. Behçet’s disease. Int J Rheum Dis. 2018;21:2057–8.
  • Davatchi F. Behcet’s disease. Int J Rheum Dis. 2014;17:355–7.
  • Mahr A, Maldini C. Épidémiologie de la maladie de Behçet [Epidemiology of Behçet’s disease] Rev Med Interne. 2014;35:81–9.
  • Zouboulis CC. Epidemiology of Adamantiades-Behçet’s disease. Ann Med Interne (Paris) 1999;150:488–98.
  • International Team for the Revision of the International Criteria for Behçet’s Disease (ITR-ICBD) The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014;28:338–47.
  • Kirkali Z, Yigitbasi O, Sasmaz R. Urological aspects of Behçet’s disease. Br J Urol. 1991;67:638–9.
  • Alizadeh F, Khorrami MH, Izadpanahi MH, Nouri-Mahdavi K, Mohammadi Sichani M. Bladder involvement in Behcet’s disease. Urol J. 2012;9:347–50.
  • Sarica K, Süzer O, Gürler A, Baltaci S, Ozdiler E, Dinçel C. Urological evaluation of Behçet patients and the effect of colchicine on fertility. Eur Urol. 1995;27:39–42.
  • Davatchi F, Akbaran M, Shahram F, Jamshidi A, Gharibdoost F, Chams C. Iran Behcet’s disease dynamic activity measure. Hung Rheumatol Suppl. 1991;32:1340.
  • Krause I, Rosen Y, Kaplan I, et al. Recurrent aphthous stomatitis in Behçet’s disease: clinical features and correlation with systemic disease expression and severity. J Oral Pathol Med. 1999;28:193–6.
  • Suzuki Kurokawa M, Suzuki N. Behcet’s disease. Clin Exp Med. 2004;4:10–20.
  • Cetinel B, Akpinar H, Tüfek I, Uygun N, Solok V, Yazici H. Bladder involvement in Behçet’s syndrome. J Urol. 1999;161:52–6.
  • Cetinel B, Obek C, Solok V, Yaycioglu O, Yazici H. Urologic screening for men with Behçet’s syndrome. Urology. 1998;52:863–5.
  • Erdoğru T, Koçak T, Serdaroğlu P, Kadioğlu A, Tellaloğlu S. Evaluation and therapeutic approaches of voiding and erectile dysfunction in neurological Behçet’s syndrome. J Urol. 1999;162:147–53.
  • Akkoç N. Update on the epidemiology, risk factors and disease outcomes of Behçet’s disease. Best Pract Res Clin Rheumatol. 2018;32:261–70.
  • Davatchi F, Shahram F, Chams-Davatchi C, et al. Behcet’s disease: from East to West. Clin Rheumatol. 2010;29:823–33.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Üroloji
Bölüm Araştırma Makaleleri
Yazarlar

Aykut Başer 0000-0003-0457-512X

Sinan Çelen 0000-0003-4309-2323

Yusuf Özlülerden 0000-0002-6467-0930

Okan Alkış 0000-0001-6116-9588

Yayımlanma Tarihi 16 Aralık 2021
Gönderilme Tarihi 29 Kasım 2021
Yayımlandığı Sayı Yıl 2021

Kaynak Göster

Vancouver Başer A, Çelen S, Özlülerden Y, Alkış O. The Effects of Behçet’s Disease on LUTS in Male Patients. HTD / HMJ. 2021;1(1):1-4.

e-ISSN: 2791-9935