BİR ARAŞTIRMA HASTANESİNDE GÖRÜLEN TRANSFÜZYON REAKSİYONLARININ DEĞERLENDİRİLMESİ

Öz

Amaç: Çalışmanın amacı, hemovijilans kapsamında kan/kan bileşeni transfüzyonu yapılan hastalarda transfüzyona bağlı advers reaksiyonların sıklığını ve tiplerini belirlemek ve bunların pandemi sırasındaki dağılımı hakkında veri elde etmektir. Gereç ve Yöntemler: Hemovijilans sistemi kapsamında izlenen kan/kan ürünü transfüzyonlarına ilişkin veriler retrospektif olarak incelendi Çalışmada, transfüzyona bağlı advers reaksiyon gelişen hastaların sosyodemografik özellikleri, transfüzyon sırasında advers reaksiyon gelişen kan ve kan bileşenleri, transfüzyona bağlı advers reaksiyonlar ve bunların ilişki ve şiddet dereceleri değerlendirildi. Bulgular: Transfüzyon merkezinde 17533 kan ve kan bileşeni transfüzyonunda 73 (420/100000) transfüzyona bağlı advers reaksiyon tespit edildi. Reaksiyonlar en sık göğüs hastalıkları uzmanları tarafından uygulanan transfüzyonlarda ve yataklı tedavi ünitelerinde görülürken, reaksiyonların %17,8'i acil servis transfüzyon uygulamaları sırasında gözlendi. Tespit edilen transfüzyon reaksiyonlarının ilişki derecesi 1-3 aralığında, reaksiyon şiddeti derecesi ise 1-2 aralığındaydı. Transfüzyonla ilişkili tüm advers reaksiyonlar akuttu. En sık görülen transfüzyon reaksiyonu trombosit transfüzyonları sırasında gözlendi. Sonuç: Covid -19 pandemisi istenmeyen transfüzyon reaksiyonlarının hemovijilansı verileri, transfüzyon güvenlik önlemlerinin planlanmasında hasta güvenliği uygulamaları için bir rehber olarak kullanılabilecek katkılar sağlayacaktır.

Anahtar Kelimeler

• Kan
• Transfüzyon reaksiyonu
• Covid -19 pandemisi

EVALUATION OF TRANSFUSION REACTIONS OBSERVED IN A RESEARCH HOSPITAL

Öz

Objective: The aim of the study was to determine the frequency and types of transfusion-related adverse reactions in patients receiving blood/blood component transfusions as part of hemovigilance and to obtain data on their distribution during the pandemic. Materials and Methods: Data on blood/blood component transfusions monitored within the hemovigilance system were retrospectively analyzed to evaluate the sociodemographic characteristics of patients with transfusion-related adverse reactions, blood and blood components that developed adverse reactions during transfusion, transfusion-related adverse reactions and their association and severity ratings. Results: At the transfusion center, 73 (420/100000) transfusion-related adverse reactions were detected in 17533 blood and blood component transfusions. Reactions were most frequent in transfusions administered by pulmonologists and in inpatient units, but 17.8% of the reactions were observed in emergency room transfusion practices. The degree of association of the transfusion reactions observed ranged from 1 to 3, and the degree of severity ranged from 1 to 2. All transfusion-related adverse events were acute. The most common transfusion reaction was observed with platelet transfusions. Conclusions: Covid-19 pandemic hemovigilance of adverse transfusion reactions data can be used as a guide for patient safety practice for planning transfusion safety measures will contribute.

Anahtar Kelimeler

• Blood
• transfusion reaction
• Covid-19 pandemic

Kaynakça

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