Investigation of Thiol/Disulfide Homeostasis in Muscle Obese Adults Doing Bodybuilding Exercise

Öz

Background: In this study, it was aimed to compare the oxidative stress levels of individuals who do bodybuilding exercises, normal weight sedentary, overweight and obese individuals and normal weight individuals who do regular physical exercise.
Materials and Methods: 122 male volunteers aged between 18-45 years were included in the study. Participants were divided into 4 different groups according to the type of exercise they were interested in and their Body Mass Index. Oxidative stress levels in individuals doing body-building exercises were compared with sedentary normal weight, obese individuals and normal weight individuals doing regular physical exercise. Serum thiol-disulfide parameters were measu-red to determine oxidative stress levels.
Results: It was observed that dynamic thiol / disulfide homeostasis was achieved in participants with normal weight and regular exercise, but dynamic thiol / disulfide homeostasis was impaired in the group doing bodybuilding exercise.
Conclusions: The results of the experiment show that we should avoid heavy exercises such as bodybuilding, and that regular and normal exercises should be encouraged.

Keywords: Exercise, Obesity, Oxidative stress, Thiol/disulfite, Bodybuilding exercise

Vücut Geliştirme Egzersizi Yapan Kas Obezi Yetişkin Bireylerde Tiyol/Disülfit Homeostazının İncelenmesi

Öz

Amaç Bu çalışmada vücut geliştirme egzersizi yapan bireylerdeki oksidatif stres düzeylerinin, sedanter normal kilolu, aşırı kilolu ve obez bireyler ve düzenli fiziksel egzersiz yapan normal kilolu bireyler ile karşılaştırarak araştırılması amaçlanmıştır. Materyal ve Metod Çalışmaya 18-45 yaşları arasında 122 gönüllü erkek katılımcı dahil edildi. Katılımcılar ilgilendikleri egzersizin şekline ve Vücut Kitle İndeksine göre 4 farklı gruba ayrıldı. Vücut geliştirme egzersizi yapan bireylerdeki oksidatif stres düzeyleri, sedanter normal kilolu, obez bireyler ve düzenli fiziksel egzersiz yapan normal kilolu bireyler ile karşılaştırıldı. Oksidatif stres düzeylerini belirlemek için serum tiyol-disülfit parametreleri ölçüldü. Bulgular Normal kilolu düzenli egzersiz yapan katılıcılarda dinamik tiyol / disülfit homeostazının sağlandığı, ancak vücut geliştirme egzersizi yapan grupta dinamik tiyol / disülfit homeostazının bozulduğunu gözlenmiştir. Sonuç Deney sonuçları vücut geliştirme egzersizi gibi ağır egzersizlerden kaçınmamızı, düzenli ve hafif egzersizlerin ise teşvik edilmesi gerektiğini göstermektedir.

Anahtar Kelimeler

• egzersiz
• obezite
• oksidatif stres
• tiyol/disülfit
• vücut geliştirme egzersizi

Kaynakça

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