Akut Koroner Sendrom ile Başvuran Hastalarda Çoklu Damar Hastalığı Oranlarının Akut Koroner Sendrom Alt Tiplerine Göre Karşılaştırılması

Yıl 2023, , 56 - 61, 27.04.2023

Veysel Tosun , Halil Fedai

https://doi.org/10.35440/hutfd.1204384

Öz

Amaç: Akut koroner sendromlar (AKS), ST elevasyonlu miyokard enfarktüsü (STEMİ), ST elevasyonsuz miyokard enfarktüsü (NSTEMİ) ve unstabil anjina pektoris (USAP)’ ten oluşan akut damar tıkanıklıkları ile seyreden hastalık grubudur. Bu yazımızda koroner anjiyografi yapılan hastalarda AKS türleri ile çoklu damar hastalığı arasındaki ilişkiyi araştırmayı amaçladık.
Materyal ve metod: Temmuz 2019 ile Eylül 2022 tarihleri arasında AKS tanısı ile koroner anjiyografi yapılan 2048 hasta çalışmaya alındı. Hastaların epikrizlerinin yanında demografik özellikleri, lipit profili ve anjiyografi raporları incelendi. STEMİ, NSTEMİ ve USAP şeklinde 3 grup oluşturularak lipit profilleri ile darlık-tıkanıklık olan damar sayıları kaydedildi.
Bulgular: 522(%25.4) STEMİ, 1116(%54.5) NSTEMİ ve 410(%24.1) USAP çalışmaya alındı. STEMİ grubu, NSTEMİ ve USAP grubuna göre daha gençti (sırasıyla p<0.001 ve p:0.043), sigara içme oranı daha yüksekti (sırasıyla p:0.043 ve p:0.027), daha yüksek LDL-K kolesterol değerlerine sahipti (sırasıyla p:0.040 ve p<0.001). Üç ve üzeri damar hastalığı NSTEMİ ve USAP gruplarına kıyasla en yüksek STEMİ grubunda saptandı (hepsi için p<0.001). LDL-K ve HbA1c değeri ile koroner tıkanıklık-darlık olan damar sayısı arasında zayıf ama pozitif anlamlı bir ilişki mevcuttu (sırasıyla r:0.163, p<0.001; r:0.349, p<0.001); HDL-K ile de negatif bir ilişki mevcuttu (r:-0.111, p:0.001).
Sonuç: STEMİ ile gelen AKS hastalarında çoklu damar hastalığının daha fazla olduğu saptandı.

Anahtar Kelimeler

akut koroner sendrom, çoklu damar hastalığı, anjiyografi, revaskülarizasyon

Destekleyen Kurum

yok

Proje Numarası

yok

Teşekkür

yok

Comparison of Multivessel Disease Rates According to Acute Coronary Syndrome Subtypes in Patients Presenting with Acute Coronary Syndrome

Öz

Background: Acute coronary syndromes (ACS) which is consist of ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI) and unstable angina pectoris (USAP) are a group of diseases with acute vascular occlusion. In this article, we aimed to investigate the relationship between ACS types and multivessel disease in patients who underwent coronary angiography.
Materials and Methods: A total of 2048 patients with ACS who underwent coronary angiography between July 2019 and September 2022 were included in the study. Demographic characteristics, lipid profile and angiography reports of the patients were examined, as well as epicrisis. Lipid profiles and the number of vessels with critical stenosis- were recorded by forming 3 groups as STEMI, NSTEMI and USAP.
Results: 522 (25.4%) STEMI, 1116 (54.5%) NSTEMI and 410 (24.1%) USAP patients were included in the study. The STEMI group was younger than the NSTEMI and USAP group (p<0.001 and p=0.043, respecti-vely), had a higher smoking rate (p=0.043 and p=0.027, respectively), had higher LDL-C values (p=0.040 and p<0.001, respectively). Three or more vessel disease was detected most in the STEMI group com-pared to the NSTEMI and USAP group (p<0.001, for all). There was a weak but positive significant corre-lation between LDL-C and HbA1c values and the number of vessels with coronary occlusion-stenosis (r:0.163, p<0.001; r:0.349, p<0.001, respectively). there was also negative correlation with HDL-C (r:-111, p=0.001).
Conclusions: Multiple vessel disease was found to be more common in ACS patients presenting with STEMI.

Key Words: Acute coronary syndrome, Multiple vessel disease, Angiography, Revascularization

Anahtar Kelimeler

akut koroner sendrom, çoklu damar hastalığı, anjiyografi, revaskülarizasyon

Proje Numarası

yok

Kaynakça

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