Antiepileptik İlaç Kullanan Çocuklarda Kemik Mineral Metabolizmasının Değerlendirilmesi

Öz

Değerli Editör, Bu yazıda ‘Antiepileptik İlaç Kullanan Çocuklarda Kemik Mineral Metabolizmasının Değerlendirilmesi’ başlıklı yazıya fizik tedavi ve rehabilitasyon uzmanı bakış açısıyla katkı sunmaya çalışacağım. Öncelikle Gençler ve ark.’larına bazen gözden kaçabilen ve komplikasyonlarla karşımıza çıkan böylesine önemli bir konudaki çalışması için teşekkürlerimi sunuyorum.

Anahtar Kelimeler

• osteoporoz
• antiepileptik ilaç
• kemik mineral metabolizması

The Evaluation of Bone Mineral Metabolism in Children on Antiepileptic Drug Therapy

Öz

Dear Editor, In this article, I will try to contribute to the article titled 'The Evaluation of Bone Mineral Metabolism in Children on Antiepileptic Drug Therapy' from the perspective of a physical therapy and rehabilitation specialist. First of all, I would like to thank Gençler et al. for their work on such an important issue that can sometimes be overlooked and comes with complications.

Anahtar Kelimeler

• osteoporosis
• antiepileptic drug
• bone mineral metabolism

Kaynakça

1. 1. Gençler A, Karasalihoğlu ST. Antiepileptik İlaç Kullanan Çocuklarda Kemik Mineral Metabolizmasının Değerlendirilmesi. Harran Üniversitesi Tıp Fakültesi Dergisi 2023;20(3):667-71.
2. 2. Bishop N, Arundel P, Clark E, Dimitri P, Farr J, Jones G, et al. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 Pediatric Official Positions. J Clin Densitom. 2014;17(2):275-80.
3. 3. Rauch F, Plotkin H, DiMeglio L , Engelbert RH, Henderson RC, Munns C, et al. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2007 Pediatric Official Positions. J Clin Densitom. 2008;11(1):22-8.
4. 4. de Putter CE, van Beeck EF, Looman CWN, Toet H, Hovius SER, Selles RW. Trends in wrist fractures in children and adolescents, 1997-2009. J Hand Surg Am. 2011;36(11):1810-1815.e2.
5. 5. DeShazo SJ, Ozmer GL, Horton KA, Weiss WM. Phenytoin is associated with increased risk of osteoporosis and fragility fractures in adult epileptic patients. J Bone Miner Metab. 2023. doi: 10.1007/s00774-023-01475-2. Online ahead of print.
6. 6. Högler W, Ward L. Osteoporosis in Children with Chronic Disease. Endocr Dev. 2015;28:176-95.
7. 7. Dernek B. Pediatrik Hastalarda Osteoporoz. Klinik Tıp Pediatri Dergisi 2018;10(1):39-43.
8. 8. Formosa MM, Christou MA, Makitie O. Bone fragility and osteoporosis in children and young adults. J Endocrinol Invest. 2023. doi: 10.1007/s40618-023-02179-0. Online ahead of print.

9. 9. Goulding A, Cannan R, Williams SM, Gold EJ, Taylor RW, Lewis-Barned NJ. Bone mineral density in girls with forearm fractures. J Bone Miner Res. 1998;13(1):143-8.
10. 10. Clark EM, Ness AR, Bishop NJ, Tobias JH. Association between bone mass and fractures in children: a prospective cohort study. J Bone Miner Res. 2006;21(9):1489-95.