Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging: An Observational Comparison

Öz

Background: This study aimed to compare sedation methods in pediatric patients undergoing mag-netic resonance imaging (MRI) using three different anesthetic agents (sevoflurane, thiopental, and propofol) regarding safety, efficacy, time management, and side effects. Materials and Methods: An observational study was conducted with 126 pediatric patients divided into three groups, each receiving one of the three sedative agents: Group S (n = 43), Group T (n = 41), and Group P (n = 42). Patients in Group S received induction with 8% sevoflurane, Group T received 5 mg kg1 of thiopental intravenously, and Group P received 2 mg kg-1 of propofol intrave-nously, followed by maintenance via infusion. Results: The mean age was 37.3 ± 2 months. Cranial MRI was most frequently requested (64.5%). Group P had higher desaturation (p = 0.029) and respiratory depression (p = 0.008) rates. Group T had the shortest induction time (p <0.001), while Group S showed the fastest wake-up times (p = 0.002; p = 0.001). Conclusions: Sevoflurane is distinguished by its rapid emergence from sedation and low incidence of side effects. Thiopental has a quick induction time, whereas propofol is associated with minimal agitation but higher respiratory complications. These findings can guide clinicians in selecting the most appropriate sedation method for pediatric MRI.

Anahtar Kelimeler

• Deep sedation
• magnetic resonance imaging
• propofol
• sevoflurane
• thiopental.

Manyetik Rezonans Görüntülemesi Geçiren Pediatrik Hastalarda Sedasyon: Gözlemsel Bir Karşılaştırma

Öz

Amaç: Bu çalışma, manyetik rezonans görüntüleme (MRG) geçiren pediatrik hastalarda üç farklı anestezik ajan (sevofluran, tiyopental ve propofol) kullanılarak yapılan sedasyon yöntemlerini güven-lik, etkinlik, zaman yönetimi ve yan etkiler açısından karşılaştırmayı amaçladı. Materyal ve Metod: Gözlemsel bir çalışma 126 pediatrik hasta ile gerçekleştirildi ve hastalar üç gruba ayrıldı; her grup üç sedatif ajanından birini aldı: Grup S (n = 43), Grup T (n = 41) ve Grup P (n = 42). Grup S'deki hastalara %8 sevofluran ile indüksiyon, Grup T'deki hastalara 5 mg kg-1 tiyopental intravenöz yolla, Grup P'deki hastalara ise 2 mg kg-1 propofol intravenöz yolla indüksiyon yapıldı ve ardından infüzyon yoluyla idame sağlandı. Bulgular: Ortalama yaş 37,3 ± 2 ay olarak belirlendi. En sık istenen MRG türü kranial MRG idi (%64,5). Grup P'de desatürasyon (p = 0,029) ve solunum depresyonu (p = 0,008) oranları daha yüksekti. Grup T en kısa indüksiyon süresine sahipti (p < 0,001), Grup S ise en hızlı uyanma sürelerini gösterdi (p = 0,002; p = 0,001). Sonuç: Sevofluran, sedasyondan hızlı derlenme ve düşük yan etki insidansı ile öne çıkmaktadır. Tiyopental, hızlı bir indüksiyon süresine sahipken, propofol minimal ajitasyon ancak daha yüksek solunum komplikasyonları ile ilişkilidir. Bu bulgular, pediatrik MRG için en uygun sedasyon yöntemi-ni seçmede klinisyenlere rehberlik edebilir.

Anahtar Kelimeler

• Derin sedasyon
• manyetik rezonans görüntüleme
• propofol
• sevofluran
• tiyopental.

Kaynakça

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