Araştırma Makalesi
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İleri Yaş Perianal Fistül Nüksünü Artırıyor Mu?

Yıl 2017, Cilt: 14 Sayı: 2, 124 - 127, 31.08.2017

Öz

Giriş ve Amaç: Perianal fistüller zor tedavi edilen
hastalıklardan birisidir. Genellikle tanısı kolaydır; ancak
ilave tetkikler gerekebilir. Yara iyileşmesinde yaş çok
önemli bir faktör olarak karşımıza çıkmaktadır. Bu
çalışmamızda, ileri yaşın perianal fistül nüksü ile bir ilgisi
olup olmadığını inceledik.
Yöntem ve Gereçler: Ocak-2010 ve Ocak-2016 tarihleri
arasında fistülotomi+küretaj yapılan 242 hasta geriye
dönük olarak incelendi. Bunlardan 18’i nüks nedeniyle en
az iki defa daha(13 hasta iki, 5 hasta üç kez) opere
edilmişti. Bu hastaların cinsiyet, yaş, fistül tipi ve dış
ağzının anal kanala uzaklığı retrospektif olarak kaydedildi.
Bulgular: Grup 1ve Grup 2’yi karşılaştırdığımızda
cinsiyet, fistül dış ağzının anal kanala olan mesafesi ve
fistül tipi açısından istatistiksel olarak anlamlı bir fark
bulunmadı. Bunun yanında ileri yaşın, fistül nüks
sıklığında etkili olduğuna dair istatistiksel olarak bir fark
tespit edilemedi.
Tartişma ve Sonuç: Yaptiğimiz bu çalişmada perianal
fistüllerin nüksünde yaş, cinsiyet, fistül ağzinin uzakliği ve
fistül tipi etkili gibi görünmemektedir. yara iyileşmesinde
yaş, önemli bir faktör olarak karşimiza çikmaktadir, fakat
bu çalişmada fistül nükslerine olan etkisi istatistiksel olarak
anlamli bulunamamiştir. 

Kaynakça

  • 1. Fujiwara T, Duscher D, Rustad KC, Kosaraju R, Rodrigues M, Whittam AJ, et al. Extracellular Superoxide Dismutase Deficiency Impairs Wound Healing in Advanced Age by Reducing Neovascularization and Fibroblast Function. Experimental dermatology. 2015.
  • 2. Sainio P. Fistula-in-ano in a defined population. Incidence and epidemiological aspects. Annales chirurgiae et gynaecologiae. 1984;73(4):219-24.
  • 3. Amato A, Bottini C, De Nardi P, Giamundo P, Lauretta A, Realis Luc A, et al. Evaluation and management of perianal abscess and anal fistula: a consensus statement developed by the Italian Society of Colorectal Surgery (SICCR). Techniques in coloproctology. 2015;19(10):595-606.
  • 4. Parthasarathi R, Gomes RM, Rajapandian S, Sathiamurthy R, Praveenraj P, Senthilnathan P, et al. Ligation of the intersphincteric fistula tract (lift) for the treatment of fistula-in-ano: tertiary care centre experience from South India. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2015.
  • 5. Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. The British journal of surgery. 1976;63(1):1-12.
  • 6. Gottgens KW, Janssen PT, Heemskerk J, van Dielen FM, Konsten JL, Lettinga T, et al. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. International journal of colorectal disease. 2015;30(2):213-9.
  • 7. Visscher AP, Schuur D, Roos R, Van der Mijnsbrugge GJ, Meijerink WJ, Felt-Bersma RJ. Longterm follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life. Diseases of the colon and rectum. 2015;58(5):533-9.
  • 8. Gottgens KW, Smeets RR, Stassen LP, Beets G, Breukink SO. Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula. International journal of colorectal disease. 2015;30(5):583-93.
  • 9. Hawkey CJ. Stem cell transplantation for Crohn's disease. Best practice & research Clinical haematology. 2004;17(2):317-25.
  • 10. Holt DR, Kirk SJ, Regan MC, Hurson M, Lindblad WJ, Barbul A. Effect of age on wound healing in healthy human beings. Surgery. 1992;112(2):293-7; discussion 7-8.
  • 11. Swift ME, Burns AL, Gray KL, DiPietro LA. Age-related alterations in the inflammatory response to dermal injury. J Invest Dermatol. 2001;117(5):1027-35.
  • 12. Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, et al. Age-dependent impairment of angiogenesis. Circulation. 1999;99(1):111-20.

Does Advanced Age Increase the Recurrence of Perianal Fistulas?

Yıl 2017, Cilt: 14 Sayı: 2, 124 - 127, 31.08.2017

Öz

Introduction: Perianal fistulas are diseases that treated
difficulty. It is usually easy to diagnose; but it may need
additional tests. Age is an important factor in wound
healing. In this study, we examined whether the advanced
age has a relevance with the recurrence of perianal fistula.
Methods: There were 242 patients between January 2010
and January 2016 with fistulotomy + curettage. These
patients had been operated at least twice because of the
recurrences(13 patients two times and 5 patients three
times). These patients' gender, age, type of fistula and
distance from external opening to the anal canal was
recorded, retrospectively.
Results: When comparing Group 1 and Group 2; was not
statistically significant in terms of the gender, distance
from external opening of the fistula to the anal canal and
fistula type. In additionally, there was no statistically
significant difference with advanced age.
Discussion and Conclusion: In this study we found that;
age, gender, distance from the opening of the fistula to the
anal canal and fistula type do not seem influential in the
recurrence of perianal fistulas. Age has emerged as an
important factor in wound healing but in this study, it was
not statistically significant at fistula recurrence.
Keywords: 

Kaynakça

  • 1. Fujiwara T, Duscher D, Rustad KC, Kosaraju R, Rodrigues M, Whittam AJ, et al. Extracellular Superoxide Dismutase Deficiency Impairs Wound Healing in Advanced Age by Reducing Neovascularization and Fibroblast Function. Experimental dermatology. 2015.
  • 2. Sainio P. Fistula-in-ano in a defined population. Incidence and epidemiological aspects. Annales chirurgiae et gynaecologiae. 1984;73(4):219-24.
  • 3. Amato A, Bottini C, De Nardi P, Giamundo P, Lauretta A, Realis Luc A, et al. Evaluation and management of perianal abscess and anal fistula: a consensus statement developed by the Italian Society of Colorectal Surgery (SICCR). Techniques in coloproctology. 2015;19(10):595-606.
  • 4. Parthasarathi R, Gomes RM, Rajapandian S, Sathiamurthy R, Praveenraj P, Senthilnathan P, et al. Ligation of the intersphincteric fistula tract (lift) for the treatment of fistula-in-ano: tertiary care centre experience from South India. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2015.
  • 5. Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. The British journal of surgery. 1976;63(1):1-12.
  • 6. Gottgens KW, Janssen PT, Heemskerk J, van Dielen FM, Konsten JL, Lettinga T, et al. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. International journal of colorectal disease. 2015;30(2):213-9.
  • 7. Visscher AP, Schuur D, Roos R, Van der Mijnsbrugge GJ, Meijerink WJ, Felt-Bersma RJ. Longterm follow-up after surgery for simple and complex cryptoglandular fistulas: fecal incontinence and impact on quality of life. Diseases of the colon and rectum. 2015;58(5):533-9.
  • 8. Gottgens KW, Smeets RR, Stassen LP, Beets G, Breukink SO. Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula. International journal of colorectal disease. 2015;30(5):583-93.
  • 9. Hawkey CJ. Stem cell transplantation for Crohn's disease. Best practice & research Clinical haematology. 2004;17(2):317-25.
  • 10. Holt DR, Kirk SJ, Regan MC, Hurson M, Lindblad WJ, Barbul A. Effect of age on wound healing in healthy human beings. Surgery. 1992;112(2):293-7; discussion 7-8.
  • 11. Swift ME, Burns AL, Gray KL, DiPietro LA. Age-related alterations in the inflammatory response to dermal injury. J Invest Dermatol. 2001;117(5):1027-35.
  • 12. Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, et al. Age-dependent impairment of angiogenesis. Circulation. 1999;99(1):111-20.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Orhan Gözeneli

Faik Tatlı

Yusuf Yücel

Ali Uzunköy

Yayımlanma Tarihi 31 Ağustos 2017
Gönderilme Tarihi 8 Haziran 2017
Kabul Tarihi 11 Ağustos 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 14 Sayı: 2

Kaynak Göster

Vancouver Gözeneli O, Tatlı F, Yücel Y, Uzunköy A. Does Advanced Age Increase the Recurrence of Perianal Fistulas?. Harran Üniversitesi Tıp Fakültesi Dergisi. 2017;14(2):124-7.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty