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1829 Apendektomi Materyalinin Retrospektif Olarak Değerlendirilmes

Yıl 2015, Cilt: 12 Sayı: 2, 193 - 199, 30.08.2015

Öz

Amaç: Akut apandisit en sık acil operasyon gerektiren akut batın nedenidir. Akut apandisit nedeni ile yapılan
apendektomilerde nadirde olsa tümörlere rastlanır. Bu çalışmada amacımız akut apandisit ön tanısı ile
yapılan apendektomilerde saptanan patolojileri geriye dönük olarak incelemektir.
Gereç-yöntem: Ocak 2008- Kasım 2014 tarihleri arasında akut apandisit ön tanısı ile ameliyat edilen ve
apendektomi materyalleri incelenen 1829 olgunun patoloji raporu geriye dönük olarak incelendi. Olguların
yaş, cinsiyet ve patolojik tanıları kaydedildi.
Bulgular: Çalışma kapsamında değerlendirilen olguların erkek/kadın oranı 1,28 olarak saptandı. Yaş
dağılımları 2 ay ile 91 yaş arasında değişmekte idi. Akut apandisitin en sık izlendiği yaş aralığı 20-29 yıl
olarak bulundu.
Olgular histopatolojik olarak incelendiğinde, olguların % 71,3'ü akut apandisit tanısı alırken % 1,2'i
apendiks neoplazisi tanısı almıştı. Negatif tanı alan olguların sayısı 497 idi. Yetişkin olgularda bu oran %25,9
iken çocuk olgularda %30,5 olarak gözlendi.
Apendektomi materyallerinin %1,6'sında insidental olarak nadir görülen patolojiler izlendi. Nadir görülen
patolojiler içerisinde 22 olguda (%1,2) neoplastik lezyon saptandı. Kadın ve erkek olgular hastalıkları
açısından karşılaştırıldığında apendiks neoplazisi gelişimi açısından farklılık izlenmedi (p=0,288).
Sonuç: Akut apandisit ön tanısı ile apendektomi uygulanan olguların apendiks materyallerinin
histopatolojik olarak incelenmesi insidental olarak benign veya malign tümörleri tespit edilebileceğinden
dolayı oldukça önemlidir.

Kaynakça

  • 1 Marudanayagam R, Williams GT, Rees BI: Review of the pathological results of 2660 appendicectomy specimens. J Gastro 2006;41(8):745-9. 2 Duzgun AP, Moran M, Uzun S, Ozmen MM, Ozer VM, Seckin S. Unusual findings in appendectomy specimens: Evaluation of 2458 cases and review of the literature. Indian J Surg 2004;66(4):221–6. 3 Jones AE, Phillips AW, Jarvis JR, Sargen K. The value of routine histopathological examination of appendicectomy specimens. BMC Surg 2007(1);7:17. 4 Akbulut S, Tas M, Sogutcu N, Arikanoglu Z, Basbug M, Ulku A, Semur H, Yagmur Y. Unusual histopathological findings in appendectomy specimens: a retrospective analysis and literature review. World J Gastroenterol 2011;17(15):1961–70. 5 Yabanoglu H, Caliskan K, Ozgur Aytac H, Turk E, Karagulle E, Kayaselcuk F, Akin Tarim M.Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Lit e r a tur e . Ir an Red Cr e s c ent Med J 2014;16(2):e12931 6 Flum DR, Koepsell T. The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis. Arch Surg 2002;137(7):799–804. 7 Kozar RA, Roslyn JJ. The appendix. In : Schwartz SI, eds. Principles of Surgery. New York: McGraw-Hill; 1999. 8 Addiss DG, Shaffer N, Fowler BS, Tauxe RV. The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 1990;132(5):910-25. 9 Jones PF. Suspected acute appendicitis: trends in management over 30 years. Br J Surg 2001(12);88:1570- 7. 10 Morrison CA, Greco DL, Torrington KG. Patterns of appendicitis at a forward-deployed United States Army Hospital: the Korea experience. Curr Surg 2000; 57(6):603-9. 11 Uzunkoy A, Akinci OF, Coskun A, Karaoglanoglu M, Erdogan M. The role of ultrasonographic investigation in the diagnosis of acute appendicitis. Ulus Travma Acil Cerrahi Derg 1998; 4(3): 202-5. 12 Ergün E, Bilaloglu P, Koflar U, Unlubay D, Temel S. Akut apandisit tanisinda opaksiz spiral BT incelemenin yeri, US ve cerrahi sonuçlari ile korelasyonu. Tanısal ve Girisimsel Radyoloji 2002;8(1): 231-6. 13 Rothrock SG, Skeoch G, Rush JJ, Johnson NE. Clinical features of misdiagnosed appendicitis in children. Ann Emerg Med 1991;20(1):45-50. 14 Khairy G. Acute appendicitis: is removal of a normal appendix still existing and can we reduce its rate? Saudi J Gastroenterol 2009;15(3):167-70. 15 Connor SJ, Hanna GB, Frizelle FA. Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies. Dis Colon Rectum 1998;41(1):75-80. 16 Charfi S1, Sellami A, Affes A, Yaïch K, Mzali R, Boudawara TS. Histopathological findings in appendectomy specimens: a study of 24,697 cases. Int J Colorectal Dis 2014;29(8):1009-12 17 In't Hof KH, van der Wal HC, Kazemier G, Lange JF. Carcinoid tumour of the appendix: an analysis of 1,485 consecutive emergency appendectomies. J Gastrointest Surg 2008;12(8):1436-8. 18 Pickhardt PJ, Levy AD, Rohrmann CA Jr, Abbondanzo SL, Kende AI. Non-Hodgkin's lymphoma of the appendix: Clinical and CT findings with pathologic correlation. AJR Am J Roentgenol 2002;178(5):1123-7. 19 Colins DC. 71000 human appendix specimens; a final report summarizing 40 years study. Am J Proctol 1963(12);14:265-81. 20 Chan W, Fu KH. Value of Routine Histopathological examination of appendices in Hong Kong. J Clin Pathol 1987;40(4):429-33. 21 Chamisa I. A clinicopathological review of 324 appendices removed for acute appendicitis in Durban, South Africa: a retrospective analysis. Ann R Coll Surg Engl 2009;91(8):688-92.

The Retrospective Evaluation of 1829 Appendectomy Specimens

Yıl 2015, Cilt: 12 Sayı: 2, 193 - 199, 30.08.2015

Öz

Purpose: Acute appedicitis is the most common cause of surgery due to acute abdomen. Rarely diagnoses of malignancy are given after acute appendectomy. We aimed to investigate pathology reports of the patients
with a prediagnosis of acute appendicitis underwent appendectomy retrospectively.
Methods: The pathology reports and the appendectomy materials of 1829 patients with a prediagnosis of
acute appendicitis underwent appendectomy between 2008 January and 2014 November were evaluated
retrospectively
Results: The male/female ratio of the patients was 1,28 in the study. The mean age of the patients was
27,9±16,7 years (range 2 months-91 years). The age range in which acute appendicitis is mostly observed
20-29 years of age.
The histopathological examination revealed that 71,3% of the cases were given the diagnosis of acute
appendicitis while 1,2% of them appendiceal neoplasia. The negative diagnosis was given in 497 cases. The
negativity ratio was 25,9% in adult cases while it was 30,5% in pediatric cases. There was no statistically
significant difference between gender with respect to presence of appendiceal neoplasia (p=0,288).
Incidentally rare pathologies were observed in 1,6% of appendectomy materials and ın 22 cases (1,2%)
neoplastic lesions detected.
Conclusions: Histopathological examination of the appendix specimens of the patients who underwent
appendectomy with a prediagnosis of acute appendicitis is very important because of incidentally diagnosis
of benign or malignant tumors.

Kaynakça

  • 1 Marudanayagam R, Williams GT, Rees BI: Review of the pathological results of 2660 appendicectomy specimens. J Gastro 2006;41(8):745-9. 2 Duzgun AP, Moran M, Uzun S, Ozmen MM, Ozer VM, Seckin S. Unusual findings in appendectomy specimens: Evaluation of 2458 cases and review of the literature. Indian J Surg 2004;66(4):221–6. 3 Jones AE, Phillips AW, Jarvis JR, Sargen K. The value of routine histopathological examination of appendicectomy specimens. BMC Surg 2007(1);7:17. 4 Akbulut S, Tas M, Sogutcu N, Arikanoglu Z, Basbug M, Ulku A, Semur H, Yagmur Y. Unusual histopathological findings in appendectomy specimens: a retrospective analysis and literature review. World J Gastroenterol 2011;17(15):1961–70. 5 Yabanoglu H, Caliskan K, Ozgur Aytac H, Turk E, Karagulle E, Kayaselcuk F, Akin Tarim M.Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Lit e r a tur e . Ir an Red Cr e s c ent Med J 2014;16(2):e12931 6 Flum DR, Koepsell T. The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis. Arch Surg 2002;137(7):799–804. 7 Kozar RA, Roslyn JJ. The appendix. In : Schwartz SI, eds. Principles of Surgery. New York: McGraw-Hill; 1999. 8 Addiss DG, Shaffer N, Fowler BS, Tauxe RV. The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 1990;132(5):910-25. 9 Jones PF. Suspected acute appendicitis: trends in management over 30 years. Br J Surg 2001(12);88:1570- 7. 10 Morrison CA, Greco DL, Torrington KG. Patterns of appendicitis at a forward-deployed United States Army Hospital: the Korea experience. Curr Surg 2000; 57(6):603-9. 11 Uzunkoy A, Akinci OF, Coskun A, Karaoglanoglu M, Erdogan M. The role of ultrasonographic investigation in the diagnosis of acute appendicitis. Ulus Travma Acil Cerrahi Derg 1998; 4(3): 202-5. 12 Ergün E, Bilaloglu P, Koflar U, Unlubay D, Temel S. Akut apandisit tanisinda opaksiz spiral BT incelemenin yeri, US ve cerrahi sonuçlari ile korelasyonu. Tanısal ve Girisimsel Radyoloji 2002;8(1): 231-6. 13 Rothrock SG, Skeoch G, Rush JJ, Johnson NE. Clinical features of misdiagnosed appendicitis in children. Ann Emerg Med 1991;20(1):45-50. 14 Khairy G. Acute appendicitis: is removal of a normal appendix still existing and can we reduce its rate? Saudi J Gastroenterol 2009;15(3):167-70. 15 Connor SJ, Hanna GB, Frizelle FA. Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies. Dis Colon Rectum 1998;41(1):75-80. 16 Charfi S1, Sellami A, Affes A, Yaïch K, Mzali R, Boudawara TS. Histopathological findings in appendectomy specimens: a study of 24,697 cases. Int J Colorectal Dis 2014;29(8):1009-12 17 In't Hof KH, van der Wal HC, Kazemier G, Lange JF. Carcinoid tumour of the appendix: an analysis of 1,485 consecutive emergency appendectomies. J Gastrointest Surg 2008;12(8):1436-8. 18 Pickhardt PJ, Levy AD, Rohrmann CA Jr, Abbondanzo SL, Kende AI. Non-Hodgkin's lymphoma of the appendix: Clinical and CT findings with pathologic correlation. AJR Am J Roentgenol 2002;178(5):1123-7. 19 Colins DC. 71000 human appendix specimens; a final report summarizing 40 years study. Am J Proctol 1963(12);14:265-81. 20 Chan W, Fu KH. Value of Routine Histopathological examination of appendices in Hong Kong. J Clin Pathol 1987;40(4):429-33. 21 Chamisa I. A clinicopathological review of 324 appendices removed for acute appendicitis in Durban, South Africa: a retrospective analysis. Ann R Coll Surg Engl 2009;91(8):688-92.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Gül Türkcü Bu kişi benim

Ayşenur Keleş Bu kişi benim

Ulaş Alabalık Bu kişi benim

Berat Soylu Bu kişi benim

İbrahim İbiloğlu Bu kişi benim

Fatma Şule Dursun Bu kişi benim

Abdullah Oğuz Bu kişi benim

Hüseyin Büyükbayram Bu kişi benim

Yayımlanma Tarihi 30 Ağustos 2015
Gönderilme Tarihi 19 Ocak 2015
Kabul Tarihi 2 Mart 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 12 Sayı: 2

Kaynak Göster

Vancouver Türkcü G, Keleş A, Alabalık U, Soylu B, İbiloğlu İ, Dursun FŞ, Oğuz A, Büyükbayram H. 1829 Apendektomi Materyalinin Retrospektif Olarak Değerlendirilmes. Harran Üniversitesi Tıp Fakültesi Dergisi. 2015;12(2):193-9.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty