Systemic Lupus Erythematosus Developed Under The Brucellosis Therapy

Yıl 2015, Cilt: 12 Sayı: 2, 284 - 286, 30.08.2015

Meltem Vural , Cemal Bes Kadriye Kart Yaşar Deniz Yılmaz Ferit Babaşov

Öz

Drug-induced lupus erythematosus is a disorder which is temporally related to continuous drug exposure and
clinical findings resolve upon discontinuation of the offending drug. Its clinical and laboratory findings are
similar to systemic lupus erythematosus (SLE). SLE induced by doxycycline, rifampicin or streptomycin are
extremely rare. We present the case of a patient who developed arthralgia, leucopenia, lymphopenia and
pleural effusion due to the doxycycline, rifampicin or streptomycin drugs treatment. 

Anahtar Kelimeler

Brucellosis, Doxycycline, Rifampicin, Streptomycin

Bruselloz Tedavisi Altında Gelişen Sistemik Lupus Eritematozus

Öz

İlaca bağlı lupus eritematozus, ilaç kullanımına bağlı ortaya çıkan ve ilacın kesilmesi sonrasında klinik
bulguların gerilemesi ile karakterize bir bozukluktur. İlaç kaynaklı lupus eritematozusun klinik ve laboratuar
bulguları sistemik lupus eritematozusun (SLE) bulguları ile benzerdir. Doksisiklin, rifampisin veya
streptomisin ile tetiklenen SLE son derece nadirdir. Bu yazıda doksisiklin, rifampisin veya streptomisin
tedavisine bağlı artralji, lökopeni, lenfopeni ve plevral efüzyon gelişen bir olgu sunulmuştur.

Anahtar Kelimeler

Bruselloz, Doksisiklin, Rifampisin, Streptomisin

Kaynakça

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