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Prediyabetik Obezler Kadınlarda Vücut Kompozisyonunu Etkileyen Klinik ve Biyokimyasal Faktörler

Yıl 2014, Cilt: 11 Sayı: 2, 130 - 137, 01.08.2014

Öz

Amaç: Obezite, diyabet gibi önemli kronik hastalıklara yol açan bir halk sağlığı problemidir. Bizde prediyabetik premenapozal obez kadınlarda biyoelektriksel empedans analiz BEA yönteminin vücut kompozisyonunu saptamada klinik kullanımını ve vücut yağının ve visseral yağın klinik ve biyokimyasal parametrelere etkisini incelemeyi amaçladık. Materyal Metod: Çalışmaya 60 normoglisemikler kadın grup 1 , 65 bozulmuş açlık glikozu BAG olan kadın grup 2 , 33 bozulmuş glukoz toleransı BGT veya BAG+BGT olan kadın grup 3 dahil edildi.Bulgular: BEA ile saptanan visseral yağ kütlesi VYK ve yağsız kütle oranı %YK , vücut yağ oranı %VY tüm gruplarda benzerdi. %VY ve VYK; boy, kilo, vücut kütle indeksi VKI , bel çevresi BÇ , kalça çevresi KÇ gibi parametreler ile korele bulundu. Ayrıca VYK prediabetik gruplarda grup 2 ve 3 AST p

Kaynakça

  • 1) Haslam DW, James WPT. Obesity. Lancet 2005;366:1197–1209.
  • 2) Pi-Sunyer FX. Health implications of obesity. Am J Clin Nutr 1991;53:1595–1603.
  • 3) World Health Organization. Prevention of Coronary Heart Disease. Report of a WHO Expert Committee. Technical Report Series. WHO: Geneva, 1982;678.
  • 4) Welty TK. Health implications of obesity in American Indians and Alaska Natives. Am J Clin Nutr 1991;53:1616–1620.
  • 5) Wang C, Hou XH, Zhang ML, Bao YQ, Zou YH, Zhong WH, Xiang KS, Jia WP. Comparison of body mass index with body fat percentage in the evaluation of obesity in Chinese. Biomed Environ Sci 2010;23(3):173-179.
  • 6) Peltz G, Aguirre MT, Sanderson M, Fadden MK. The role of fat mass index in determining obesity. Am J Hum Biol 2010;22(5):639-647.
  • 7) Lee K, Lee S, Kim YJ, Kim YJ. Waist circumference, dual-energy X-ray absortiometrically measured abdominal adiposity, and computed tomographically derived intra-abdominal fat area on detecting metabolic risk factors in obese women. Nutrition 2008;24(7- 8):625-631.
  • 8) Dervaux N, Wubuli M, Megnien JL, Chironi G, Simon A. Comparative associations of adiposity measures with cardiometabolic risk burden in a s ymp t oma t i c s u b j e c ts. A t h e r o s c l e r o sis 2008;201(2):413-417.
  • 9) Lukaski HC. Methods for the assessment of human body composition: traditional and new. Am J Clin Nutr 1987;46(4):537-556.
  • 10) Berker D, Koparal S, Işik S, Paşaoğlu L, Aydin Y, Erol K, Delibaşi T, Güler S. Compatibility of different methods for the measurement of visceral fat in different body mass index strata. Diagn Interv Radiol 2010;16(2):99-105.
  • 12) Nagaya T, Yoshida H, Takahashi H, Matsuda Y, Kawai M. Body mass index (weight/height2) or percentage body fat by bioelectrical impedance analysis: which variable better reflects serum lipid profile? Int J Obes Relat Metab Disord 1999;23:771-774.
  • 13) Peltz G, Aguirre MT, Sanderson M, Fadden MK. The role of fat mass index in determining obesity. Am J Hum Biol 2010;22(5):639-647.
  • 14) Gómez-Ambrosi J, Silva C, Galofré JC, Escalada J, Santos S, Gil MJ, Valentí V, Rotellar F, Ramírez B, Salvador J, Frühbeck G. Body adiposity and type 2 diabetes: increased risk with a high body fat percentage even having a normal BMI. Obesity (Silver Spring) 2011;19(7):1439-1444.
  • 15) Chang CJ, Wu CH, Lu FH, Wu JS, Chiu NT, Yao WJ. Discriminating glucose tolerance status by regions of interest of dual-energy X-ray absorptiometry. Clinical implications of body fat distribution. Diabetes Care 1999;22(12):1938-1943.
  • 16) Yu Y, Venners SA, Wang B, Brickman WJ, Zimmerman D, Li Z, Wang L, Liu X, Tang G, Xing H, Xu X, Wang X. Association of central adiposity with prediabetes and decreased insulin sensitivity in rural Chinese normal-weight and overweight women. Metabolism 2010;59(7):1047-1053.
  • 17) Qiao Q, Nyamdorj R. Is the association of type II diabetes with waist circumference or waist-to-hip ratio stronger than that with body mass index? Eur J Clin Nutr 2010;64(1):30-34.
  • 18) Unwin N, Harland J, White M, Bhopal R, Winocour P, Stephenson P, Watson W, Turner C, Alberti KG. Body mass index, waist circumference, waist-hip ratio, and glucose intolerance in Chinese and Europid adults in Newcastle, UK. J Epidemiol Community Health 1997;51(2):160-166.
  • 19) Hofsø D, Nordstrand N, Johnson LK, Karlsen TI, Hager H, Jenssen T, Bollerslev J, Godang K, Sandbu R, Røislien J, Hjelmesaeth J. Obesity-related cardiovascular risk factors after weight loss: a clinical trial comparing gastric bypass surgery and intensive lif e st y l e i n t e r v e n ti o n . Eu r J En d o c ri n o l 2010;163(5):735-745.
  • 20) Huxley R, Mendis S, Zheleznyakov E, Reddy S, Chan J. Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literature. Eur J Clin Nutr 2010;64(1):16- 22.
  • 21) Mochizuki K, Miyauchi R, Misaki Y, Shimada M, Kasezawa T, Tohyama K, Goda T. Accumulation of visceral fat is positively associated with serum ALT and γGTP activities in healthy and preclinical middle-aged Japanese men. J Nutr Sci Vitaminol (Tokyo) 2011;57(1):65-73.
  • 22) Eguchi Y, Mizuta T, Sumida Y, Ishibashi E, Kitajima Y, Isoda H, Horie H, Tashiro T, Iwamoto E, Takahashi H, Kuwashiro T, Soejima S, Kawaguchi Y, Oda Y, Emura S, Iwakiri R, Ozaki I, Eguchi T, Ono N, Anzai K, Fujimoto K, Koizumi SJ. The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. Gastroenterol 2011;46:70-78.
  • 23) Verrijken A, Francque S, Mertens I, Talloen M, Peiffer F, Van Gaal L. Visceral adipose tissue and inflammation correlate with elevated liver tests in a cohort of overweight and obese patients. Int J Obes (Lond) 2010;34(5):899-907.
  • 24) Ruhl CE, Everhart JE. Trunk fat is associated with increased serum levels of alanine aminotransferase in the United States. Gastroenterology 2010;138(4):1346-1356.
  • Song HR, Yun KE, Park HS. Relation between alanine aminotransferase concentrations and visceral fat accumulation among nondiabetic overweight Korean women. Am J Clin Nutr 2008;88(1):16-21.
  • 25) Fernandes RA, Rosa CS, Buonani C, Oliveira AR, Freitas Junior IF. The use of bioelectrical impedance to detect excess visceral and subcutaneous fat. J Pediatr (Rio J) 2007;83:529–534.
  • 26) Ryo M, Maeda K, Onda T, Katashima M, Okumiya A, Nishida M, Nishida M, Yamaguchi T, Funahashi T, Matsuzawa Y, Nakamura T, Shimomura I. A new simple method for the measurement of visceral fat accumulation by bioelectrical impedance. Diabetes Care 2005;28:451–453
  • 27) Watson S, Blundell HL, Evans WD, Griffiths H, Newcombe RG, Rees DA. Can abdominal bioelectrical impedance refine the determination of visceral fat from waist circumference? Physiol Meas 2009;30(7):53-58

Clinical and Biochemical Factors Influence the Body Composition in Prediabetic Obese Women

Yıl 2014, Cilt: 11 Sayı: 2, 130 - 137, 01.08.2014

Öz

Background: Obesity is a public-health problem related with important chronic diseases such as diabetes. We aimed to investigate the clinical utility of bioelectrical impedance analysis BIA in determination of body composition and influence of body fat and visceral fat on clinical and metabolic parameters in premenopausal obese women with prediabetes.Methods: Sixty normoglycemic subjects group 1 , 65 subjects with impaired fasting glucose IFG group 2 and 33 subjects with impaired glucose tolerance IGT or IFG+IGT group 3 were included. Results: Visceral fat mass VF and percentage of fat free mass FFM% , body fat BF% determined by BIA were similar in both groups. BF% and VF has been found to be correlate with other body composition parameters such as height, weight, body mass index BMI , waist circumference WC , hip circumference HC ; additionally, VF showed positive correlation with AST p

Kaynakça

  • 1) Haslam DW, James WPT. Obesity. Lancet 2005;366:1197–1209.
  • 2) Pi-Sunyer FX. Health implications of obesity. Am J Clin Nutr 1991;53:1595–1603.
  • 3) World Health Organization. Prevention of Coronary Heart Disease. Report of a WHO Expert Committee. Technical Report Series. WHO: Geneva, 1982;678.
  • 4) Welty TK. Health implications of obesity in American Indians and Alaska Natives. Am J Clin Nutr 1991;53:1616–1620.
  • 5) Wang C, Hou XH, Zhang ML, Bao YQ, Zou YH, Zhong WH, Xiang KS, Jia WP. Comparison of body mass index with body fat percentage in the evaluation of obesity in Chinese. Biomed Environ Sci 2010;23(3):173-179.
  • 6) Peltz G, Aguirre MT, Sanderson M, Fadden MK. The role of fat mass index in determining obesity. Am J Hum Biol 2010;22(5):639-647.
  • 7) Lee K, Lee S, Kim YJ, Kim YJ. Waist circumference, dual-energy X-ray absortiometrically measured abdominal adiposity, and computed tomographically derived intra-abdominal fat area on detecting metabolic risk factors in obese women. Nutrition 2008;24(7- 8):625-631.
  • 8) Dervaux N, Wubuli M, Megnien JL, Chironi G, Simon A. Comparative associations of adiposity measures with cardiometabolic risk burden in a s ymp t oma t i c s u b j e c ts. A t h e r o s c l e r o sis 2008;201(2):413-417.
  • 9) Lukaski HC. Methods for the assessment of human body composition: traditional and new. Am J Clin Nutr 1987;46(4):537-556.
  • 10) Berker D, Koparal S, Işik S, Paşaoğlu L, Aydin Y, Erol K, Delibaşi T, Güler S. Compatibility of different methods for the measurement of visceral fat in different body mass index strata. Diagn Interv Radiol 2010;16(2):99-105.
  • 12) Nagaya T, Yoshida H, Takahashi H, Matsuda Y, Kawai M. Body mass index (weight/height2) or percentage body fat by bioelectrical impedance analysis: which variable better reflects serum lipid profile? Int J Obes Relat Metab Disord 1999;23:771-774.
  • 13) Peltz G, Aguirre MT, Sanderson M, Fadden MK. The role of fat mass index in determining obesity. Am J Hum Biol 2010;22(5):639-647.
  • 14) Gómez-Ambrosi J, Silva C, Galofré JC, Escalada J, Santos S, Gil MJ, Valentí V, Rotellar F, Ramírez B, Salvador J, Frühbeck G. Body adiposity and type 2 diabetes: increased risk with a high body fat percentage even having a normal BMI. Obesity (Silver Spring) 2011;19(7):1439-1444.
  • 15) Chang CJ, Wu CH, Lu FH, Wu JS, Chiu NT, Yao WJ. Discriminating glucose tolerance status by regions of interest of dual-energy X-ray absorptiometry. Clinical implications of body fat distribution. Diabetes Care 1999;22(12):1938-1943.
  • 16) Yu Y, Venners SA, Wang B, Brickman WJ, Zimmerman D, Li Z, Wang L, Liu X, Tang G, Xing H, Xu X, Wang X. Association of central adiposity with prediabetes and decreased insulin sensitivity in rural Chinese normal-weight and overweight women. Metabolism 2010;59(7):1047-1053.
  • 17) Qiao Q, Nyamdorj R. Is the association of type II diabetes with waist circumference or waist-to-hip ratio stronger than that with body mass index? Eur J Clin Nutr 2010;64(1):30-34.
  • 18) Unwin N, Harland J, White M, Bhopal R, Winocour P, Stephenson P, Watson W, Turner C, Alberti KG. Body mass index, waist circumference, waist-hip ratio, and glucose intolerance in Chinese and Europid adults in Newcastle, UK. J Epidemiol Community Health 1997;51(2):160-166.
  • 19) Hofsø D, Nordstrand N, Johnson LK, Karlsen TI, Hager H, Jenssen T, Bollerslev J, Godang K, Sandbu R, Røislien J, Hjelmesaeth J. Obesity-related cardiovascular risk factors after weight loss: a clinical trial comparing gastric bypass surgery and intensive lif e st y l e i n t e r v e n ti o n . Eu r J En d o c ri n o l 2010;163(5):735-745.
  • 20) Huxley R, Mendis S, Zheleznyakov E, Reddy S, Chan J. Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literature. Eur J Clin Nutr 2010;64(1):16- 22.
  • 21) Mochizuki K, Miyauchi R, Misaki Y, Shimada M, Kasezawa T, Tohyama K, Goda T. Accumulation of visceral fat is positively associated with serum ALT and γGTP activities in healthy and preclinical middle-aged Japanese men. J Nutr Sci Vitaminol (Tokyo) 2011;57(1):65-73.
  • 22) Eguchi Y, Mizuta T, Sumida Y, Ishibashi E, Kitajima Y, Isoda H, Horie H, Tashiro T, Iwamoto E, Takahashi H, Kuwashiro T, Soejima S, Kawaguchi Y, Oda Y, Emura S, Iwakiri R, Ozaki I, Eguchi T, Ono N, Anzai K, Fujimoto K, Koizumi SJ. The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. Gastroenterol 2011;46:70-78.
  • 23) Verrijken A, Francque S, Mertens I, Talloen M, Peiffer F, Van Gaal L. Visceral adipose tissue and inflammation correlate with elevated liver tests in a cohort of overweight and obese patients. Int J Obes (Lond) 2010;34(5):899-907.
  • 24) Ruhl CE, Everhart JE. Trunk fat is associated with increased serum levels of alanine aminotransferase in the United States. Gastroenterology 2010;138(4):1346-1356.
  • Song HR, Yun KE, Park HS. Relation between alanine aminotransferase concentrations and visceral fat accumulation among nondiabetic overweight Korean women. Am J Clin Nutr 2008;88(1):16-21.
  • 25) Fernandes RA, Rosa CS, Buonani C, Oliveira AR, Freitas Junior IF. The use of bioelectrical impedance to detect excess visceral and subcutaneous fat. J Pediatr (Rio J) 2007;83:529–534.
  • 26) Ryo M, Maeda K, Onda T, Katashima M, Okumiya A, Nishida M, Nishida M, Yamaguchi T, Funahashi T, Matsuzawa Y, Nakamura T, Shimomura I. A new simple method for the measurement of visceral fat accumulation by bioelectrical impedance. Diabetes Care 2005;28:451–453
  • 27) Watson S, Blundell HL, Evans WD, Griffiths H, Newcombe RG, Rees DA. Can abdominal bioelectrical impedance refine the determination of visceral fat from waist circumference? Physiol Meas 2009;30(7):53-58
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Mehmet Ali Eren Bu kişi benim

Ayşe Nur Torun Bu kişi benim

Turgay Ulaş Bu kişi benim

Timuçin Aydoğan Bu kişi benim

Mehmet Demir Bu kişi benim

Tevfik Sabuncu Bu kişi benim

Yayımlanma Tarihi 1 Ağustos 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 11 Sayı: 2

Kaynak Göster

Vancouver Eren MA, Torun AN, Ulaş T, Aydoğan T, Demir M, Sabuncu T. Prediyabetik Obezler Kadınlarda Vücut Kompozisyonunu Etkileyen Klinik ve Biyokimyasal Faktörler. Harran Üniversitesi Tıp Fakültesi Dergisi. 2014;11(2):130-7.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty