Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma

İbrahim Söğüt; Güngör Kanbak

doi:10.5606/fng.btd.2016.030

Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma

Öz

Alkol birçok organ ve dokuda (özellikle beyin ve karaciğer) doza ve kullanım süresine bağlı olarak hasar oluşturabilen bir toksindir. Doğum öncesi(prenatal) dönemde anne tarafından kullanılan alkol, fetal alkol sendromuna neden olabilmektedir. Fetal alkol sendromu ilk olarak 1970’li yıllarınbaşında, alkol kullanma alışkanlığını gebelikte de sürdüren anneden doğan bebeklerde görülen büyüme bozukluğu, yüz bölgesi anormallikleri vemental gerilik olarak tanımlanmıştır. Gebeliğin ilk üç ayında kullanılan alkol fetus üzerinde düşüğe, organogenez döneminde organlarda hasara,gebeliğin ikinci üç aylık döneminde hücrelerdeki fetotoksik etkisiyle merkezi sinir sisteminde ağır hasara neden olabilmektedir. Bu derlemede doğumöncesi alkol kullanımı sonucu oluşan oksidatif stres ve antioksidan savunma mekanizması hakkında bilgiler sunulmuştur.

Anahtar Kelimeler

Antioksidanlar,fetal alkol sendromu,oksidatif stres,gebelikte alkol kullanımı

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

-

Bölüm

Derleme

Yazarlar

İbrahim Söğüt

Güngör Kanbak Bu kişi benim

Yayımlanma Tarihi

1 Haziran 2016

Gönderilme Tarihi

1 Mayıs 2016

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2016 Cilt: 2 Sayı: 2

DOI

https://doi.org/10.5606/fng.btd.2016.030

IZ

https://izlik.org/JA55GK59JJ

Kaynak Göster

RIS / Bibtex

APA

Söğüt, İ., & Kanbak, G. (2016). Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, 2(2), 165-169. https://doi.org/10.5606/fng.btd.2016.030

AMA

1.Söğüt İ, Kanbak G. Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi. 2016;2(2):165-169. doi:10.5606/fng.btd.2016.030

Chicago

Söğüt, İbrahim, ve Güngör Kanbak. 2016. “Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 2 (2): 165-69. https://doi.org/10.5606/fng.btd.2016.030.

EndNote

Söğüt İ, Kanbak G (01 Haziran 2016) Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 2 2 165–169.

IEEE

[1]İ. Söğüt ve G. Kanbak, “Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma”, İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, c. 2, sy 2, ss. 165–169, Haz. 2016, doi: 10.5606/fng.btd.2016.030.

ISNAD

Söğüt, İbrahim - Kanbak, Güngör. “Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 2/2 (01 Haziran 2016): 165-169. https://doi.org/10.5606/fng.btd.2016.030.

JAMA

1.Söğüt İ, Kanbak G. Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi. 2016;2:165–169.

MLA

Söğüt, İbrahim, ve Güngör Kanbak. “Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, c. 2, sy 2, Haziran 2016, ss. 165-9, doi:10.5606/fng.btd.2016.030.

Vancouver

1.İbrahim Söğüt, Güngör Kanbak. Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi. 01 Haziran 2016;2(2):165-9. doi:10.5606/fng.btd.2016.030