Clinical Overview of the Role of Epigenetics in Human Diseases

Öz

In recent years, a growing number of studies have shown that epigenetic changes have significant effects on the disease process. In this process, epigenetic knowledge has gone beyond genetics with the great contributions of technological developments. New findings in epigenetics not only enable us to better understand the disease-related factors but also open new doors for therapeutic intervention. In this review, the concept of epigenetics and the importance of epigenetics in human diseases are examined.

Anahtar Kelimeler

• Epigenetics,genetics,cancer,human diseases

İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış

Öz

Son yıllarda sayısı giderek artan çalışmalar, epigenetik değişikliklerin hastalık süreci üzerinde önemli etkilerinin olduğunu ortaya koymaktadır. Bu süreçte teknolojik gelişmelerin de büyük katkıları ile epigenetik bilgi genetiğin ötesine taşınmıştır. Epigenetik konusunda elde edilen yeni bulgular sadece hastalıklarla ilişkili faktörleri daha iyi anlamamızı sağlamakla kalmaz, aynı zamanda terapötik girişim için yeni kapılar da açmaktadır. Bu derlemede, epigenetik kavramı ve insan hastalıklarında epigenetiğin önemi irdelenmiştir.

Anahtar Kelimeler

• Epigenetik,genetik,kanser,insan hastalıkları

Kaynakça

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