Molluscum Contagiosum with Metaplastic Ossification: A Very Rare Case

Yıl 2020, , 304 - 309, 31.08.2020

Hülya Etem

https://doi.org/10.38079/igusabder.670423

Öz

Molluscum Contagiosum (MC) is a common, benign viral disease. It usually affects the skin and rarely mucosal membranes. Although this disease can be seen in all age groups, it is most commonly seen in children and sexually active adults. In MC disease, lesions characterized by a single or multiple, 3-5 mm diameter papules with a navel in the middle can be seen all over the body, except for the palm and soles. Histopathological examination shows intracytoplasmic Molluscum bodies also known as Henderson-Paterson bodies. In this case, an acne-like lesion with a size of 0.5 cm on the left malar region was observed on the face of a 27-year-old female patient. After the lesion was extirpated, the diagnosis of MC showing metaplastic ossification was made on histopathological examination. This case is presented because metaplastic ossification is very rare in MC disease.

Anahtar Kelimeler

Molluscum Contagiosum, metaplastic ossification, dermatology

Metaplastik Ossifikasyon Gösteren Molluscum Contagiosum: Çok Nadir Bir Olgu

Öz

Molluscum Contagiosum (MC) sık görülen benign, viral bir hastalıktır. Çoğunlukla deriyi, nadiren mukozal membranları etkiler. Bu hastalık her yaş grubunda görülebilmekle birlikte, daha çok çocuklarda ve daha az olarak seksüel aktif erişkinlerde görülmektedir. MC hastalığında avuç içi ve ayak tabanı hariç vücudun her yerinde genellikle 3-5 mm çapında tek veya çok sayıda, ortasında göbeklenme gösteren papüllerle karakterize lezyonlar görülebilir. Histopatolojik incelemede Henderson-Paterson cisimcikleri olarak da bilinen intrasitoplazmik Molluscum cisimleri görülür. Bu olguda yirmi yedi yaşında kadın hastanın, yüzünde, sol malar bölge üzerinde 0.5 cm boyutunda sivilceye benzeyen lezyon gözlendi. Lezyon ekstirpe edildikten sonra histopatolojik incelemede metaplastik ossifikasyon gösteren MC tanısı konuldu. MC hastalığında metaplastik ossifikasyon çok nadir görüldüğü için bu olgu sunulmuştur. 

Anahtar Kelimeler

Molluscum Contagiosum, Metaplastik Ossifikasyon, dermatoloji, Molluskum Kontagiozum

Kaynakça

• Vanhooteghem O, Henrijean A, de la Brassinne M. Epidemiology, clinical picture and treatment of molluscum contagiosum: literature review. Ann Dermatol Venereol. 2008;135:326-32.
• Dave S, Thappa DM, Karthikeyan K. Disseminated and disfiguring molluscum contagiosum in a patient with rheumatoid arthritis taking methotrexate. Clin Exp Dermatol. 2007;33:347.
• Schornack MM, Siemsen DW, Bradley EA, et al. Ocular manifestations of molluscum contagiosum. Clin Exp Optom. 2006;89:390.
• Fornatora ML, Reich RF, Gray RG, Freedman PD. Intraoral molluscum contagiosum: a report of case and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92:318-320.
• Nandhini G, Rajkumar K, Kanth KS, et al. Molluscum contagiosum in a 12-years-old child-report of a case and review of literature. J Int Oral Health. 2015;7:63-66.
• Diven DG. An overview of poxviruses. J Am Acad Dermatol. 2001;44:1-14.
• Cotell SL, Roholt NS. Images in clinical medicine. Molluscum contagiosum in a patient with the acquired immunodeficiniency syndrome. N Engl J Med. 1998;338:888.
• Naert F, Lachapella JM. Multipl lesions of Mollucum contagiosum with metaplastic ossification. Am. J. Dermapathol. 1989;11(3):238-241.
• Al-Daraji W. Osteo-nevus of Nanta (osseous metaplasia in a benign intradermal melanocytic nevus): an uncommon phenomen. Dermatol Online J. 2007;13(4):16.
• Conlin PA, Jimenez – Quintero LP, Rapini RP. Osteomas of the skin revisited: a clinicopathologic review of 74 cases. Am J Dermatopathol. 2002;24(6):479-83.
• Kanitakis J, Claudy A. Mummified ossified melanocytic nevus. Eur J Dermatol. 2000;10(6):466-7.
• Sasaki S, Mitsuhashi Y, Ito Y. Osteo-nevus of Nanta: a case report and review of the Japanese literature. J Dermatol. 1999;26(3):183-8.