Investigation of Thermal and Electrical Properties of Dipeptides Containing Fmoc Group

Yıl 2022, Cilt: 8 Sayı: 1, 91 - 101, 30.06.2022

Eray Çalışkan , Fatih Biryan , Kenan Koran

https://doi.org/10.29132/ijpas.1011511

Öz

In this study, a series of dipeptide compounds were synthesized as a result of the reaction of Fmoc group protected amino acids and amino acids with carboxylic acid end methyl esters with triazine reagent. The structures of the synthesized compounds were characterized by FT-IR, 1H and 13C APT NMR spectroscopy techniques. The thermal decomposition temperatures of the compounds were determined by thermogravimetric analysis method in nitrogen atmosphere from room temperature to 600 oC. When the TGA curves of the dipeptides were examined, it was observed that the thermal decomposition temperatures varied between 181 and 200 oC. The electrical behavior of the dipeptides was investigated with an impedance analyzer in the frequency range of 1-30 kHz. The variation in dielectric constant, dielectric loss, susceptibility and impedance parameters were investigated as a function of frequency. The dielectric constant of the dipeptides ranges from 5.99 to 6.67.

Anahtar Kelimeler

Dipeptide, Dielectric analysis, Thermal properties

Fmoc Grubu Taşıyan Dipeptit Yapılarının Termal ve Elektriksel Özelliklerinin İncelenmesi

Öz

Bu çalışmada Fmoc grubu ile korunmuş amino asitler ile karboksilik asit ucu metil ester olan amino asitlerin reaksiyonu bir seri dipeptit bileşikleri sentezlendi. Sentezlenen bileşiklerin yapısı FT-IR, 1H-13C NMR spektroskopi teknikleriyle karakterize edildi. Bileşiklerin termal bozunma sıcaklıkları oda sıcaklığından 600oC’ye kadar azot atmosferinde termogravimetrik analiz yöntemiyle belirlendi. Dipeptitlerin TGA eğrileri incelendiğinde termal bozunma sıcaklıkları 181 ile 200 oC aralığında değiştiği gözlendi. Dipeptitlerin 1-30 kHz frekans aralığında empedans analizör cihazı ile elektriksel davranışları incelendi. Dielektrik sabiti, dielektrik kayıp, suseptans ve empedans parametrelerindeki değişim frekansın bir fonksiyonu olarak araştırıldı. Dipeptitlerin dielektrik sabiti 5.99 ile 6.67 aralığında değişmektedir.

Anahtar Kelimeler

Dipeptit, Dielektriksel analiz, Termal özellik

Kaynakça

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