COVID-19 Pandemisi Parkinson Hastalarının Motor Olmayan Bulgularını Nasıl Etkiledi?

Öz

Amaç: Çalışmanın amacı COVID-19 pandemisinin Parkinson hastalarının motor olmayan bulguları üzerindeki değişimini incelemek, değişim miktarlarını sağlıklı bireylerle karşılaştırmak ve pandemi döneminde Parkinson hastalarının koronafobi ile motor olmayan bulguları arasındaki ilişkiyi incelemekti. Gereç ve Yöntem: Çalışmaya 53 Parkinson hastası ve 53 sağlıklı birey dahil edildi. Katılımcıların uyku kalitesi (Pittsburgh Uyku Kalitesi İndeksi), yorgunluk şiddeti (Yorgunluk Şiddet Ölçeği) ve depresif bulguları (Geriatrik Depresyon Ölçeği) pandemi dönemi ve pandemi öncesi dönem olmak üzere iki ayrı dönem için değerlendirildi. Pandemi dönemindeki koronafobiyi değerlendirmek için Koronavirüs 19 Fobisi Ölçeği kullanıldı. Bulgular: Pandemi öncesi dönemle karşılaştırıldığında pandemi döneminde hastaların motor olmayan semptomlarını değerlendiren ölçeklerin puanlarının istatistiksel olarak anlamlı derecede arttığı belirlendi (p<0,05). Sağlıklı bireylerle karşılaştırıldığında, hastaların Yorgunluk Şiddet Ölçeği puanındaki değişimin istatistiksel olarak anlamlı derecede daha yüksek olduğu bulundu (p=0,027). Pandemi sırasında hastaların Koronavirüs 19 Fobisi Ölçeği ile Geriatrik Depresyon Ölçeği puanları arasında pozitif yönde zayıf düzeyde bir korelasyon saptandı (rho=0,357, p=0,009). Sonuç: COVID-19 pandemisi sırasında Parkinson hastalarının uyku kalitesi bozulmuş, yorgunluk şiddeti ve depresif bulguları artmıştır. Ayrıca pandemi döneminde yorgunluk şiddetindeki değişimin sağlıklı bireylere kıyasla daha belirgin olduğu görülmüştür. Hastaların artmış koronafobi düzeyi kötüleşen depresif bulgularla ilişkilidir. Parkinson hastalarının motor olmayan bulguları bu tür küresel sağlık krizlerinden olumsuz etkilenebileceğinden önleyici ve destekleyici yönetim stratejilerinin geliştirilmesi önemli olacaktır. Anahtar Kelimeler: COVID-19, motor olmayan bulgu, Parkinson hastalığı.

Anahtar Kelimeler

• COVID-19
• motor olmayan bulgu
• Parkinson hastalığı

How Did the COVID-19 Pandemic Affect the Non-Motor Symptoms of Patients with Parkinson's Disease?

Öz

Objective: The study aimed to assess the effect of the COVID-19 pandemic on non-motor symptoms in patients with Parkinson’s disease, compare these changes with healthy controls and investigate the relationship between coronaphobia and non-motor symptoms in patients with Parkinson’s disease during the pandemic. Material and Methods: The study included 53 patients with Parkinson's disease and 53 healthy controls. Participants' sleep quality (Pittsburgh Sleep Quality Index), fatigue severity (Fatigue Severity Scale), and depressive symptoms (Geriatric Depression Scale) were evaluated for two distinct time periods: the pre-pandemic period and the pandemic period. The COVID-19 Phobia Scale was administered to assess coronaphobia during the pandemic. Results: Compared to the pre-pandemic period, non-motor symptoms significantly increased during the pandemic period (p<0.05). The change in these non-motor symptoms during the pandemic compared to the pre-pandemic period was similar between patients and the healthy control group (p>0.05). During the pandemic, a weak positive correlation was observed between the COVID-19 Phobia Scale and Geriatric Depression Scale scores in patients (rho=0.357, p=0.009). Conclusion: During the COVID-19 pandemic, patients with Parkinson’s disease experienced worsened sleep quality, increased fatigue severity and depressive symptoms. Increased coronaphobia levels in patients were associated with worsening depressive symptoms. Since non-motor symptoms in patients with Parkinson’s disease may adversely be affected by such global health crises, developing preventive and supportive management strategies will be crucial. Keywords: COVID-19, non-motor symptom, Parkinson’s disease.

Anahtar Kelimeler

• COVID-19
• non-motor symptom
• Parkinson’s disease

Kaynakça

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