Obezite ve COVID-19

Yıl 2020, Cilt: 5 Sayı: 2, 211 - 214, 30.06.2020

Beda Özalp , Nilgün Seremet Kürklü

Öz

Özet

Şiddetli Akut Solunum Sendromu Koronavirüs-2 (SARS-CoV-2), Dünya Sağlık Örgütü (DSÖ) tarafından Koronavirus Hastalığı 2019 (COVID-19) olarak adlandırılan hastalığın etkeni olan yeni tip koronavirüstür. İlk olarak Çin’in Wuhan şehrinde ortaya çıkmış ve tüm dünyaya hızla yayılmıştır. İnsandan insana çok hızlı bulaşabilen COVID-19, yaş ile ilişkili olmakla birlikte hipertansiyon, diyabet, kardiyovasküler hastalıklar vb. komorbiditesi olan bireylerde daha şiddetli seyretmektedir. Günümüzün önemli bir halk sağlığı sorunu olan obezite; bulaşıcı olmayan kronik hastalıkların oluşma riskini arttırmakta ve solunum yolu hastalıklarının gelişmesine neden olmaktadır. Obezite ile COVID-19 arasındaki ilişkiyi ortaya koyacak mekanizma net olarak bilinmemesine rağmen yapılan çalışmalarla, vücut ağırlığındaki artışın COVID-19 enfeksiyonu şiddetini de arttığını gösterilmiştir. Sonuç olarak tüm dünyada ve ülkemizde önemli bir sağlık sorunu olan COVID-19 hastalığının tedavisinde; diyabet, hipertansiyon vb hastalıkların yanı sıra hastalığın seyrinin hafifletilmesi ve yoğun bakımdaki hasta sayısının ve kalış süresinin azaltılması amacıyla obeziteye de dikkat edilmesi gerekmektedir. Bu derlemede obezite ve COVID-19 arasındaki ilişki ve olası mekanizmalar tartışılmıştır.

Anahtar Kelimeler: Obezite, beden kütle indeksi, COVID-19, inflamasyon.

Abstract

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a new type of coronavirus which is the cause of disease named the Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO), first appeared in Wuhan, China and spread all over the world rapidly. COVID-19, which can be transmitted rapidly from person to person, is age-related; however, it is more severe in people with comorbidities such as hypertension, diabetes, cardiovascular disease, etc. Being one of the serious health issues today, obesity increases the risk of non-communicable diseases and causes the development of respiratory diseases. Although the mechanism between obesity and COVID-19 is not clearly known, studies have shown that the increase in body weight is positively associated with the severity of COVID-19 infection, the need for treatment in the intensive care unit, and the rates of mechanical ventilation. Consequently, obesity should be considered in the prevention and treatment of COVID-19 disease, which is a critical health issue across the world and in our country, in addition to chronic diseases, to reduce the course of the disease and complications. In this study, the relationship and possible mechanisms between obesity and COVID-19 are discussed.

Keywords: Obesity, body mass index, COVID-19, inflammation.

Anahtar Kelimeler

obezite, Beden kütle indeksi, COVID-19, İnflamasyon

Kaynakça

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