TARİHİ GEÇMİŞ KOMPOZİT REZİNLERİ KULLANMAK MÜMKÜN MÜ? : FTIR ANALİZİ

Yıl 2023, Cilt: 2 Sayı: 1, 5 - 11, 07.02.2023

Seda Özmen , Bengü Doğu , Ayşe Aslı Şenol , Bora Korkut , Bilge Tarçın , Pınar Yılmaz Atalı

Öz

Amaç: Bu çalışmanın amacı; son kullanma tarihleri 1 yıl, 2 yıl ve 3 yıl geçmiş rezin kompozitlerin (RK) dönüşüm derecelerini karşılaştırarak kullanımlarındaki güven aralığını değerlendirmektir. Materyal ve Metod: Üç farklı RK'den (Herculite XRV-Ultra A2-dentin, son kullanma tarihi 3 yıl ve 1 yıl geçmiş; Herculite Classic A2, son kullanma tarihi 2 yıl geçmiş; Kerr) 9 adet disk (8 x2 mm) hazırlandı (n=3). RK silikon kalıplara yerleştirildi, her iki tarafı şeffaf bantlar ile kapatıldı ve LED ışıklı cihaz ile (Valo, Ultradent) ile 20 sn parmak basıncı altında polimerizasyonu takiben numuneler 37°C'de 24 saat distile suda bekletildi. Dönüşüm derecesini (%DC) belirlemek için Fourier Dönüşümü Kızılötesi Spektrometre (FT-IR, JASCO) ile örnekleme kullanılarak polimerize olmuş ve olmamış kompozitler üzerinde spektral analizler yapıldı. Ortaya çıkan FT-IR spektrumu, 20 °C ortam sıcaklığında 4000–400 cm-1 spektral aralığında kaydedildi; kullanılan çözünürlük dört tarama ile 4 cm-1’dir. Veriler SPSS (SPSS Inc.) ile tek yönlü varyans analizi (ANOVA) ve Tukey testleri kullanılarak analiz edildi. Anlamlılık düzeyi p<0,05 olarak alındı. Bulgular: En yüksek ortalama %DC, 1 yıllık son kullanma tarihi geçmiş RK grubu için kaydedilirken (H-6: 68,80 ± 4,544), bunu 2 yıllık son kullanma tarihi geçmiş RK grubu (H- 12: 68,268 ± 2,695) takip etmiştir. En düşük ortalama %DC 3 yıl üstü RK grubu için kaydedilmiştir (H-24: 68.032 ± 4.641). Üç grup arasında %DC değerleri açısından istatistiksel olarak anlamlı bir fark bulunmadı (P=0,096). Sonuç: Bu çalışmanın limitasyonları dahilinde; son kullanma tarihleri üzerinden 1, 2 ve 3 yıl geçmiş kompozitler benzer %DC sonuçları gösterdi. Klinisyenlerin, üreticiler tarafından önerilen son kullanım tarihi talimatlarını takip etmeleri gerekmektedir.

Anahtar Kelimeler

DÖNÜŞÜM DERECESİ, FT-IR, LED, KOMPOZİT REZİN, SON KULLANMA TARİHİ

IS IT POSSIBLE TO USE EXPIRED RESIN COMPOSITES: FTIR ANALYSIS

Öz

Aim: The aim of this study is to evaluate the confidence interval in the use of resin composites (RC) with expiration dates of 1-year, 2-years and 3-years by comparing the conversion degrees. Material and Methods: 9 discs (8x2 mm) were prepared from three RC (n=3), (Herculite XRV-Ultra A2-dentine; 3-years expired, 1-year expired. Herculite Classic A2, 2-years expired, Kerr). RC were placed in silicone molds, covered with mylar strips on both sides and polymerized with a LED light-curing unit (Valo, Ultradent) under finger pressure for 20s. The polymerized samples were kept in distilled water for 24 hours at 37C. Spectral analyses were performed on uncured and cured composites using sampling with Fourier Transform Infrared (FT-IR, JASCO) to determine the degree of conversion rates (DC%). The resulting FT-IR spectrum was recorded in the spectral range of 4000–400 cm-1 at ambient temperature of 20 °C; the resolution used was 4 cm-1 with four scans. Data were analyzed with SPSS (SPSS Inc.) using one-way Analysis of variance (ANOVA) and Tukey tests. Significance level was set at p<0.05. Results: The highest mean DC% was recorded for the RC group with 1-year expiration date (H-6: 68,80 ± 4,544), followed by the 2-years expired RC group (H- 12: 68,268 ± 2,695). The lowest mean DC% was recorded for the RC group with 3-years of expiration date (H-24: 68,032 ± 4,641). There was no statistically significant difference between the three groups in terms of DC% values (p=0.096). Conclusion: Within the limitations of this study, composites with expiration dates of 1-, 2-, and 3-years showed similar DC% results. Clinicians are required to follow the expiration date guidelines recommended by the manufacturers’.

Anahtar Kelimeler

COMPOSITE RESIN, CONVERSION DEGREE, FT-IR, LED, EXPIRATION DATE

Kaynakça

• A.D.A. (2003). Dental Product Standards Development Vocabulary, Standard No.33. National Standards Institute/ American Dental Association, Chicago.
• Aziz, Adel A. (2019). EVALUATION OF MECHANICAL PROPERTIES OF EXPIRED AND NON-EXPIRED RESIN COMPOSITE. A COMPARATIVE STUDY. Egyptian Dental Journal, 65(1-January (Fixed Prosthodontics, Dental Materials, Conservative Dentistry & Endodontics)), 619-628.
• Bajaj, Sanjay, Singla, Dinesh, & Sakhuja, Neha. (2012). Stability testing of pharmaceutical products. Journal of applied pharmaceutical science, 2(3), 129-138.
• Bal, Bilge Turhan, Nalan Sönmez, DDS, Barkin Bavbek, DDS, & Cihan Akçaboy, DDS. (2011). Cytotoxicity of Composite Resins Before and After Expiration Date: Preliminary Report. New York State Dental Journal, 77(3), 31. Calheiros, Fernanda C, Daronch, Márcia, Rueggeberg, Frederick A, & Braga, Roberto R. (2008). Degree of conversion and mechanical properties of a BisGMA: TEGDMA composite as a function of the applied radiant exposure. Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials, 84(2), 503-509.
• Chen, Min-Huey, Chen, Ci-Rong, Hsu, Seng-Haw, Sun, Shih-Po, & Su, Wei-Fang. (2006). Low shrinkage light curable nanocomposite for dental restorative material. Dental Materials, 22(2), 138-145.
• Clark, G. (1991). Shelf life of medical devices, guidance document. Division of Small Manufacturers Assistance, C.
• D’Alpino, Paulo Henrique Perlatti, Vismara, Marcos Vinícius Gonçalves, González, Alejandra Hortencia Miranda, & de Oliveira Graeff, Carlos Frederico. (2014). Free radical entrapment and crystallinity of resin composites after accelerated aging as a function of the expiration date. journal of the mechanical behavior of biomedical materials, 36, 82-89.
• Daronch, M, Rueggeberg, FA, & De Goes, MF. (2005). Monomer conversion of pre-heated composite. Journal of dental research, 84(7), 663-667.
• de Lange, Cees, Bausch, J Robert, & Davidson, Carel L. (1983). The influence of shelf life and storage conditions on some properties of composite resins. The Journal of prosthetic dentistry, 49(3), 349-355.
• Donohue, J, & Apostolou, S. (1990). Shelf-life prediction for radiation-sterilized plastic devices. Med Dev Diag Indu, 12(1), 124-129.
• Drummond, James L. (2008). Degradation, fatigue, and failure of resin dental composite materials. Journal of dental research, 87(8), 710-719.
• Eliguzeloglu Dalkilic, Evrim, Donmez, Nazmiye, Kazak, Magrur, Duc, Bugra, & Aslantas, Akif. (2019). Microhardness and water solubility of expired and non-expired shelf-life composites. The International journal of artificial organs, 42(1), 25-30.
• Ferracane, Jack L. (1985). Correlation between hardness and degree of conversion during the setting reaction of unfilled dental restorative resins. Dental Materials, 1(1), 11-14.
• Ferracane, Jack L. (2006). Hygroscopic and hydrolytic effects in dental polymer networks. Dental Materials, 22(3), 211-222.
• Ferracane, Jack L. (2011). Resin composite—state of the art. Dental Materials, 27(1), 29-38.
• Ferracane, JL, Moser, JB, & Greener, EH. (1985). Ultraviolet light-induced yellowing of dental restorative resins. The Journal of prosthetic dentistry, 54(4), 483-487.
• Garcia, Lucas da Fonseca Roberti, Roselino, L de M, Pires-de-Souza, F de C, & Consani, Simonides. (2010). Evaluation of the conversion degree, microhardness, and surface roughness of composite resins used after their expiration date. Gen Dent, 58(6), e262-267.
• Geurtsen, W. (2000). Biocompatibility of resin-modified filling materials. Critical Reviews in Oral Biology & Medicine, 11(3), 333-355.
• Gungor, Ahmet Yalcin, Alkis, Huseyin, & Turkkahraman, Hakan. (2016). Can brackets be bonded with a composite resin after expiration date? The International journal of artificial organs, 39(2), 84-86.
• Hansel, C, Leyhausen, G, Mai, UEH, & Geurtsen, W. (1998). Effects of various resin composite (co) monomers and extracts on two caries-associated micro-organisms in vitro. Journal of dental research, 77(1), 60-67.
• Hondrum, SO, & Fernandez Jr, R. (1997). The storage stability of dental composite resins: seven-year results. General dentistry, 45(4), 382-389.
• IMAZATO, Satoshi, TARUMI, Hisashi, KOBAYASHI, Kyoko, HIRAGURI, Hideki, ODA, Kozo, & TSUCHITANI, Yasuhiko. (1995). Relationship between the degree of conversion and internal discoloration of light-activated composite. Dental materials journal, 14(1), 23-30,101.
• Krishnan, V Kalliyana, & Yamuna, V. (1998). Effect of initiator concentration, exposure time and particle size of the filler upon the mechanical properties of a light‐curing radiopaque dental composite. Journal of oral rehabilitation, 25(10), 747-751.
• Lyon, Robbe C, Taylor, Jeb S, Porter, Donna A, Prasanna, Hullahalli R, & Hussain, Ajaz S. (2006). Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences, 95(7), 1549-1560.
• Mendes, Luis C, Tedesco, Andrea D, & Miranda, Mauro S. (2005). Determination of degree of conversion as function of depth of a photo-initiated dental restoration composite. Polymer Testing, 24(4), 418-422.
• Moharamzadeh, Keyvan, Brook, Ian M, & Van Noort, Richard. (2009). Biocompatibility of resin-based dental materials. Materials, 2(2), 514-548.
• Nie, J, Lindén, LÅ, Rabek, JF, Fouassier, JP, Morlet‐Savary, F, Scigalski, F, . . . Andrzejewska, E. (1998). A reappraisal of the photopolymerization kinetics of triethyleneglycol dimethacrylate initiated by camphorquinone‐N, N‐dimethyl‐p‐toluidine for dental purposes. Acta polymerica, 49(4), 145-161.
• Nikolina, Spyropoulou, Anastasia, Plevritaki, Konstantinos, Masouras, & Panagiotis, Lagouvardos. Color Stability of Expired Restorative Dental Composite Resins.
• Øysæd, H, Ruyter, IE, & Sjøvik Kleven, IJ. (1988). Release of formaldehyde from dental composites. Journal of dental research, 67(10), 1289-1294.
• Sabbagh, Joseph, Nabbout, Fidele, Jabbour, Edgard, & Leloup, Gaetane. (2018). The effect of expiration date on mechanical properties of resin composites. Journal of International Society of Preventive & Community Dentistry, 8(2), 99.
• Shajii, Leylanaz, & Santerre, J Paul. (1999). Effect of filler content on the profile of released biodegradation products in micro-filled bis-GMA/TEGDMA dental composite resins. Biomaterials, 20(20), 1897-1908.
• Silva, Eduardo Moreira da, Almeida, Giselle Soares, Poskus, Laiza Tatiana, & Guimarães, José Guilherme Antunes. (2008). Relationship between the degree of conversion, solubility and salivary sorption of a hybrid and a nanofilled resin composite. Journal of Applied Oral Science, 16(2), 161-166.
• Talreja, Nidhi, Singla, Shilpy, & Shashikiran, ND. (2017). Comparative Evaluation of Bond Strength and Microleakage of Standard and Expired Composite at Resin-Dentin Interface: An in vitro Study. International journal of clinical pediatric dentistry, 10(1), 1.
• Tirapelli, Camila, Panzeri, Fernanda de Carvalho, Panzeri, Heitor, Pardini, Luiz Carlos, & Zaniquelli, Osvaldo. (2004). Radiopacity and microhardness changes and effect of X-ray operating voltage in resin-based materials before and after the expiration date. Materials Research, 7(3), 409-412.
• Tosun, Gul, Ozturk, Nilgun, Sener, Yagmur, & Gunduz, Beniz. (2009). Effect of light curing units and storage time on the degree of conversion of fissure sealants. Archives of Oral Research, 5(2).
• Yap, AUJ, Lee, HK, & Sabapathy, R. (2000). Release of methacrylic acid from dental composites. Dental Materials, 16(3), 172-179.