PREDICTIVE VALUE OF C-REACTIVE PROTEIN/ALBUMİN RATIO IN THE DEVELOPMENT OF CONTRAST-INDUCED NEPHROPATHY IN PATIENTS WITH ACUTE ISCHEMIC STROKE TREATED PERCUTANEOUSLY

Yıl 2022, , 130 - 139, 10.03.2022

Erdoğan Yaşar

https://doi.org/10.33715/inonusaglik.1028554

Cited By: 1

Öz

Contrast induced nephropathy (CIN) is known to play an important role in acute kidney injury. The purpose of this study was to determine the predictive effect of the CRP/albumin ratio (CAR) in the detection of CIN in patients with acute ischemic stroke (AIS) treated percutaneously. A total of 148 acute stroke patients treated percutaneously were included in the study. In the study population, groups were determined according to the development of CIN. The CAR value was calculated by dividing the CRP value by the albumin value. CIN developed in 26 (17%) patients. DM (p=0.031) and HT (p=0.014) diseases were observed at higher rate in the CIN group. Glucose (p<0.001), contrast amount (p<0.001), WBC (p=0.020), NIHSS0 score (p=0.001), and CAR (p<0.001) were higher in the CIN (+) group compared to the CIN (-) group. A cutoff point of 0.393 for CAR was identified with 80.7% sensitivity and 92.6% specificity to predict CIN. The CAR was found to be significantly higher in CIN patients and was also identified as an independent predictor of the development of CIN.

Anahtar Kelimeler

Acute ischemic stroke, C-reactive protein to albumin ratio, Contrast induced nephropathy

Teşekkür

I would like to thank Dr Yahya Akalın from the Neurology Department of Malatya Training and Research Hospital for his support.

Perkutan Olarak Tedavi Edilen Akut İskemik İnme’li Hastalarda Kontrast Kaynaklı Nefropati Gelişiminde C-Reaktif Protein /Albumin Oranının Öngörü Değeri

Öz

Kontrast kaynaklı nefropatinin (KKN) akut böbrek hasarında önemli rolü olduğu bilinmektedir. Çalışmamızda, perkütan olarak tedavi edilen akut iskemik inmeli hastalarda KKN tespitinde CRP/albümin oranının (CAO) tahmin edici etkisini ortaya koymak amaçlanmıştır. Perkütan olarak tedavi edilen toplam 148 akut inme hastası çalışmaya dahil edilmiştir. Çalışma popülasyonunda gruplar KKN gelişimine göre iki gruba ayrıldı. CAO değeri, CRP değerinin albümin değerine bölünmesiyle elde edildi. 26 (%17) hastada KKN gelişti. DM (p=0.031) ve HT (p=0.014) hastalıkları KKN grubunda daha yüksek oranda izlendi. Glikoz (p<0.001), kontrast miktarı (p<0.001), WBC (p=0.020), NIHSS0 skoru (p=0.001) ve CAO (p<0.001) KKN (+) grubunda KKN (-)'e göre daha yüksekti. CAO için 0,393'lük bir eşik değeri, KKN'yi tahmin etmek için %80.7 duyarlılık ve %92.6 özgüllük ile belirlendi. CAO, KKN hastalarında anlamlı olarak daha yüksek bulundu ve ayrıca KKN gelişiminin bağımsız bir öngörücüsü olarak tanımlandı.

Anahtar Kelimeler

Akut iskemik inme, C-reaktif protein/albümin oranı, Kontrast kaynaklı nefropati

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