COVID-19 GEÇİREN ÇOCUK OLGULARIN DEĞERLENDİRİLMESİ

Yıl 2022, Cilt: 10 Sayı: 2, 753 - 762, 20.06.2022

Erhan Berk Muhammed Selçuk Sinanoğlu Nuriye Aslı Melekoğlu

https://doi.org/10.33715/inonusaglik.1049361

Öz

Son dönemde çocuk yaş gurubu Covid-19 hastalarının artması nedeni ile çocuk hastalar için tanı ve tedavi kriterlerinin oluşturulması önem kazanmaktadır. Bu çalışmamızda, hastane başvurusu sonrası Covid-19 tanısı konulan çocuk hastalarımızın tanı, tedavi ve laboratuar bulgularını değerlendirerek çocuklardaki Covid-19 tanı ve tedavi kriterlerinin oluşumuna katkı sağlamayı amaçladık Bu çalışmaya, pandemi sürecinde acil servis ve polikliniğe başvuruları sonrasında Covid-19 tanısı konularak ayaktan veya yatırılarak tedavi edilen çocuk yaş gurubu 220 olgu dahil edildi. Hastaların 142’si (%64.5) erkekti ve 18’inin (%8.1) kronik hastalığı vardı. Hastaların yaşları 7-17 arasında değişmekte olup, yaş ortalamaları 13,4±2,26 yıl idi. Klinik ve laboratuar bulgularının değerlendirilmesi sonucu 38 çocuk hastaneye yatırılarak tedavi edildi. Covid-19 enfeksiyonu tanı ve tedavisi için vakaların sınıflandırılması ve bu sınıflandırmaya göre tedavi ve takibinin yapılması mortalite ve komplikasyonların önlenmesi açısından önemlidir.

Anahtar Kelimeler

Covid-19 enfeksiyonu, Çocuk, Klinik bulgular

Evaluation of Child Cases with Covid-19

Öz

Due to the recent increase in pediatric Covid-19 patients, it is important to establish diagnostic and treatment criteria for pediatric patients. In this study, we aimed to contribute to the formation of the diagnosis and treatment criteria for Covid-19 in children by evaluating the diagnosis, treatment and laboratory findings of our pediatric patients who were diagnosed with Covid-19 after hospital admission. 220 cases in the pediatric age group who were diagnosed with Covid-19 and treated as outpatients or inpatients after applying to the emergency service and polyclinic during the pandemic were included in this study. Of the patients, 142 (64.5%) were male and 18 (8.1%) had chronic disease. The ages of the patients ranged from 7 to 17, with a mean age of 13.4±2.26 years. As the result of the evaluation of clinical and laboratory findings, 38 children were treated after hospitalization. Classification of cases for the diagnosis and treatment of Covid-19 infection, and treatment and follow-up according to this classification are important in terms of preventing mortality and complications.

Anahtar Kelimeler

Clinical findings, Covid-19 infection, Pediatric

Kaynakça

• Aktar, F. ve Sağır, H. (2021). Pediatrik COVID-19 ve yaklaşımı. Dicle Med J., 48,166-175.
• Cao, Q., Chen, Y. C., Chen, C. L. ve Chiu, C. H. (2020). SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Formos Med Assoc., 119(3), 670-673.
• Chen, Z. M., Fu, J. F., Shu, Q., Chen, Y. H., Hua, C. Z., Li, F. B., ...Zhang, Y. Y. (2020). Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus. World Journal of Pediatrics, 16(3), 240-246.
• Fan, B. E., Chong, V. C. L., …Chan, S. S. W. (2020). Hematologic parameters in patients with COVID-19 infection [published correction appears in Am J Hematol. 2020 Nov; 95(11):1442]. Am J Hematol., 95(6), E131-E134.
• Kalkan, İ. A. ve Aktar, F. (2020). In: Coronavirus Disease 2019 (COVID-19): Turkey perspective (s. 89-95). Taşova Y. ve Çelen M. K. (Ed.). Ankara: Hipokrat yayıncılık.
• Karbuz, A., Akkoc, G., Demirdag, T. B., Ciftdogan, D. Y., Ozer, A., Cakir, D., ...Kara, A. (2021). Epidemiological, Clinical, and Laboratory Features of Children With COVID-19 in Turkey. Front Pediatr., 9, 631547. doi:10.3389/fped.2021.631547
• Kardeş, H. ve Örnek, Z. (2020). COVID-19 Pandemisine pediatrik yaklaşım. Türk Diyab Obez / Turk J Diab Obes., 4(2), 170-176.
• Lippi, G. ve Plebani, M. (2020). The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks. Clin Chem Lab Med., 58(7), 1063-1069.
• Lippi, G. ve Plebani, M. (2020). Laboratory abnormalities in patients with COVID-2019 infection. Clin Chem Lab Med., 58(7), 1131-1134.
• Lippi, G., Plebani, M. ve Henry, B. M. (2020). Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis. Clin Chim Acta., 506, 145-148.
• Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S. ve Manson J. J (2020). HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosupression. Lancet. 395(10229), 1033-1034.
• Multisystem Infammatory Syndrome in Children (MIS-C 2019) Associated with Coronavirus Disease 2019 (COVID-19). Centers for Disease Control and Prevention (CDC) Health Advisory. 14 Mayıs 2020 tarihinde CDCHAN-00432. https://emergency.cdc.gov/han/2020/han00432.asp adresinden erişildi.
• Pediatric Intensive Care Society (2020). PICS Statement: Increased number of reported cases of novel presentation of multi-system inflammatory disease. 12.11.2021 tarihinde https://picsociety.uk/wpcontent/uploads/2020/04/PICS-statement-re-novel-KD-C19-presentation-v2-27042020.pdf. adresinden erişildi.
• Perlman, S. (2020). Another Decade, another coronavirus. N Engl J Med., 382(8), 760-762.
• Poudel, A., Poudel, Y., Adhikari, A., Aryal, B. B., Dangol, D., Bajracharya, T., ...Gautam, R. (2021). D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19. PLoS One., 16(8):e0256744.
• Şenyiğit, A. (2021). COVID-19 pandemisi. Klinik, tanı, tedavi ve korunma. Dicle Med J., 48, 176-186.
• Shen, K., Yang, Y., Wang, T., Zhao, D., Jiang, Y., Jin, R., ...Lin, L., (2019). China national clinical research center for respiratory diseases. Natl. Cent. Child. Health Beijing China 223–231.
• Sun, D., Li, H., Lu, X. X., Xiao, H., Ren, J., …Zhang, F. R. (2020). Clinical features of severe pediatric patients with corona virüs disease 2019 in Wuhan: a single center’s observational study. World J Pediatr, 16, 251-259.
• T.C. Sağlık Bakanlığı Halk Sağlığı Müdürlüğü COVID-19 Çocuk Hasta Yönetimi Rehberi. Bilimsel Danışma Kurulu Çalışması (2021, Mayıs). T.C. Sağlık Bakanlığı COVID-19 Bilgilendirme Platformu.
• Ustundag, G., Yilmaz-Ciftdogan, D., Kara-Aksay, A., Sahin, A., Ekemen-Keles, Y., Orsdemir-Hortu, H., ...Yilmaz, N. (2021). COVID-19 in healthy children: What is the effect of household contact? [published online ahead of print, 2021 Jun 18]. Pediatr Int. 10.1111/ped.14890. doi:10.1111/ped.14890
• Üzel, V. H., Yılmaz, K., Şen, V., Aktar, F., Karabel, M., Yolbaş, İ., ...Söker, M. 2021). Evaluation of hematological parameters of children diagnosed with COVID-19: Single-center experience. Turk Arch Pediatr, 56(5), 463-468.
• World Health Organization (WHO 2019). Director-General’s Statement on IHR Emergency Committee on Novel Coronovirus (2019-nCoV). 1 Mayıs 2020 tarihinde https://www.who.int/dg/speeches/detail/who-director-general-s-statement-on-ihr-emergency-committee-on-novel-coronavirus-(2019-ncov) adresinden erişildi.
• Xia, W., Shao, J., Guo, Y., Peng, X., Li, Z. ve Hu, D. (2020). Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults. Pediatr Pulmonol, 55(5), 1169-1174.
• Yonker, L. M., Shen, K. ve Kinane, T. B. (2020). Lessons unfolding from pediatric cases of COVID‐19 disease caused by SARS‐CoV‐2 infection. Pediatric Pulmonology, 55(5), 1085-1086.