Muş İlinde Covid-19 Pandemisi Öncesi ve Sürecinde Toxoplasma Gondii, Rubella ve Sitomegalovirüs Seroprevalansının Karşılaştırılması

Yıl 2024, Cilt: 12 Sayı: 2, 511 - 520, 20.06.2024

Ayfer Koca , Irmak Icen Taskın

https://doi.org/10.33715/inonusaglik.1417256

Öz

Bu çalışmanın amacı Muş ilindeki gebelerde Toksoplazma gondii (T. gondii), rubella ve sitomegalovirüs (CMV) seroprevalansını ve avidite testi ile bu etkenlerin primer infeksiyon oranlarını belirlemektir. Ek olarak, Covid-19 pandemisi sırasında uygulanan önlem ve koruma tedbirlerinin hamile kadınlarda T. gondii, rubella ve CMV prevelansına etkisi de araştırıldı. 2018-2021 yılları arasında, Muş Devlet Hastanesi Kadın Hastalıkları ve Doğum polikliniğine başvuran gebelerin serum örneklerinden IgG ve IgM antikor düzeyleri enzim bağlı immünosorbent tahlili (ELISA) ve kemilüminesans immünolojik tahlili (CLIA) ile incelendi. Yüksek ve düşük avidite testleri, enzim bağlantılı floresans tahlili (ELFA) ile incelendi. Gebelerde T. gondii IgG antikorunun (%28) seroprevalansının düşük olması ve 102 gebenin 38’inde düşük avidite tespiti bu parazitin intrauterin hayat için risk oluşturabileceğini göstermektedir. Rubella IgG (%89) ve CMV IgG (%99) antikorlarının seroprevalansının ve de aviditesinin yüksek olmasından dolayı düşük oranda risk taşıdığı saptandı. Covid-19 önlem ve koruma tedbirlerinin rubella ve CMV prevalansında anlamlı bir azalmaya neden olduğu ancak T.gondii prevalansına etkisi olmadığı belirlendi.

Anahtar Kelimeler

Covid-19, Sitomegalovirüs, Rubella, Seroprevalans, Toxoplazma gondii

COMPARISON SEROPREVALENCE OF TOXOPLASMA GONDII, RUBELLA, AND CYTOMEGALOVIRUS IN MUŞ PROVINCE BEFORE AND DURING THE COVID-19 PANDEMİC

Öz

The aim of this study is to determine the seroprevalence of Toxoplasma gondii (T. gondii), rubella and cytomegalovirus (CMV) and the primary infection rates of these agents with avidity test in pregnant women in Muş province. Additionally, the effect of prevention and protection measures implemented during the Covid-19 pandemic on the prevalence of T. gondii, rubella and CMV in pregnant women was also investigated. Between 2018 and 2021, IgG and IgM antibodies in the serum samples of pregnant women who applied to the Department of Gynecology and Obstetrics polyclinic of Muş State Hospital were examined by enzyme-linked immunosorbent assay (ELISA) and chemiluminescence immunoassay (CLIA). High and low avidity assays were examined by enzyme linked fluorescence assay (ELFA). Low seroprevalence of T. gondii IgG antibody (28%) and the detection of low avidity detection in 38 of 102 pregnant women indicate that this parasite may be a risk for intrauterine life. Rubella IgG (89%) and CMV IgG (99%) antibodies were found to carry a low risk due to their high seroprevalence and avidity. It was determined that Covid-19 prevention and protection measures caused a significant decrease in the prevalence of rubella and CMV, but had no effect on the prevalence of T.gondii.

Anahtar Kelimeler

Covid-19, Cytomegalovirus, Rubella, Seroprevalence, Toxoplasma gondii

Kaynakça

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