Total Kalça ve Diz Artroplasti Hastalarının Covid-19 Korkusunun Ameliyat Öncesi Anksiyete ve Ameliyat Sonrası Analjezik Gereksinimi ile İlişkisi
Yıl 2024,
Cilt: 12 Sayı: 3, 801 - 812, 21.10.2024
Remziye Cici
,
Ahmet Özdemir
,
Gülnaz Kızılkaya
,
Meral Özkan
Öz
Total kalça ve diz artroplasti hastalarında Covid-19 korkusunun ameliyat öncesi anksiyete ve ameliyat sonrası analjezik gereksinimi ile ilişkisini belirlemek amacıyla yapıldı. Tanımlayıcı türdeki çalışma, Mart 2022-2023 tarihlerinde Türkiye’nin doğusunda bir hastanenin ortopedi kliniğinde artroplasti planlanmış 331 hastayla yapıldı. Çalışmada covid-19 korkusu, durumluk kaygı ölçeği ve vizüel analog ağrı skalası kullanıldı. Hastaların yaş ortalamasının 61.9±14.4 olduğu, %52.0’sinin total diz artroplastisi geçirdiği ve Covid-19 korku puanı ile durumluk kaygı puanı arasında ilişkinin olmadığı belirlendi. Covid-19 korku puanı ile opioid gereksinimi arasında ameliyatın birinci ve ikinci gününde pozitif yönde anlamlı ilişki belirlendi. Covid-19 korku puanı ile non-steroid antiinflamatuar ilaç (NSAİİ) gereksinimi arasında ameliyatın sıfırıncı, birinci ve ikinci gününde pozitif yönde zayıf ilişki saptandı. Parasetamol kullanımı arasında ise birinci ve ikinci gün negatif yönde zayıf ilişki saptandı. Ameliyat öncesi hastaların yaşadığı Covid-19 korkusunun ameliyat öncesi anksiyete ile ilişkili olmadığı ve ameliyat sonrası NSAİİ ve opioidler grubu analjezik kullanımını artırdığı saptandı.
Kaynakça
- Acar, K., Acar, H., Demir, F. & Eti Aslan, F. (2016). Cerrahi sonrası ağrı insidansı ve analjezik kullanım miktarının belirlenmesi. ACU Sağlık Bil Derg, 2, 85–91.
- Ahorsu, D. K., Lin, C. Y., Imani, V., Saffari, M., Griffiths, M. D. & Pakpour, A. H. (2020). The Fear of COVID-19 Scale: Development and ınitial validation. International Journal of Mental Health and Addiction, 20(3), 1537–1545. https://doi.org/10.1007/s11469-020-00270-8
- Arpaci, I., Karataş, K. & Baloğlu, M. (2020). The development and initial tests for the psychometric properties of the COVID-19 Phobia Scale (C19P-S). Personality and Individual Differences, 164(April), 110108. https://doi.org/10.1016/j.paid.2020.110108
- Aşcı, M. (2019). Total di̇z artroplasti̇si̇nde korku ve anksi̇yeteni̇n yaşam kali̇tesi ve ı̇şlevsel sonuçlara etki̇si̇. Bozok Tıp Dergisi, 100, 139–143. https://doi.org/10.16919/bozoktip.528492
- Ay, F. & Alpar, S. E. (2010). Postoperatif ağrı ve hemşirelik uygulamaları. Ağrı, 22(1), 21–29. http://www.ncbi.nlm.nih.gov/pubmed/20209411
- Aydınak, S., Yalçın, C. Ö. & Abudayyak, M. (2018). Psychiatric adverse effects of non-steroidal analgesic anti-inflammatory drugs. Journal of Literature Pharmacy Sciences, 7(1), 61–72. https://doi.org/10.5336/pharmsci.2017-58076
- Bakioğlu, F., Korkmaz, O. & Ercan, H. (2021). Fear of COVID-19 and positivity: Mediating role of ıntolerance of uncertainty, depression, anxiety, and stress. International Journal of Mental Health and Addiction, 19, 2369–2382. https://doi.org/https://doi.org/10.1007/s11469-020-00331-y
- Balkaya, A. N., Karaca, Ü., Yılmaz, C. & Ata, F. (2021). COVID-19 pandemisinde elektif cerrahi uygulanacak hastaların preoperatif anksiyete düzeylerinin değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 47(2), 233-239).
- Baskan, S., Oken, F., Kılcı, O., Dılek, K., Tırın, H., Yıldırım, O., Incı, F. & Ornek, D.(2020).Comparison of adductor canal block and local infi ltration analgesia techniques for postoperative analgesia in gonarthrosis patients receiving a total knee prosthesis. Turk J Clin Lab, 11(2), 6-11.
- Brown, T.S., Bedard, N.A., Roja, E.O., Anthony, C.A., Schwarzkopf, R., Barnes, C.L., Stambough, J.B., Mears,S.C., Edwards, P.K., Nandi, S., Prieto, H.A., Parvizi,J. (2020). The Effect of the COVID-19 Pandemic on Electively Scheduled Hip and Knee Arthroplasty Patients in the United States. J Arthroplasty. Jul, 35(7S):S49-S55. doi: 10.1016/j.arth.2020.04.052.
- Dagli, R., Avcu, M., Metin, M., Kiymaz, S. & Ciftci, H. (2019). The effects of aromatherapy using rose oil (Rosa damascena Mill.) on preoperative anxiety: A prospective randomized clinical trial. European Journal of Integrative Medicine, 26(November 2018), 37–42. https://doi.org/10.1016/j.eujim.2019.01.006
- Demir, S. G. & Erdil, F. (2013). Effectiveness of home monitoring according to the Model of Living in hip replacement surgery patients. Journal of Clinical Nursing, 22(9–10), 1226–1241. https://doi.org/10.1111/jocn.12255
- Doğan, R., Kaplan Serin, E. & Bağcı, N. (2021). Fear of COVID 19 and social effects in liver transplant patients. Transplant Immunology, 69(October). https://doi.org/10.1016/j.trim.2021.101479
- Duivenvoorden, T., Vissers, M. M., Verhaar, J. A. N., Busschbach, J. J. V., Gosens, T., Bloem, R. M., Bierma-Zeinstra, S. M. A. & Reijman, M. (2013). Anxiety and depressive symptoms before and after total hip and knee arthroplasty: A prospective multicentre study. Osteoarthritis and Cartilage, 21(12), 1834–1840. https://doi.org/10.1016/j.joca.2013.08.022
- Ennis, Z. N., Dideriksen, D., Vægter, H. B., Handberg, G. & Pottegård, A. (2016). Acetaminophen for chronic pain: A Systematic review on efficacy. Basic and Clinical Pharmacology and Toxicology, 118(3), 184–189. https://doi.org/10.1111/bcpt.12527
- Erlenwein, J., Müller, M., Falla, D., Przemeck, M., Pfingsten, M., Budde, S., Quintel, M. & Petzke, F. (2017). Clinical relevance of persistent postoperative pain after total hip replacement – a prospective observational cohort study. J Pain Res, 10, 2183–2193. https://doi.org/https://doi.org/10.2147/JPR.S137892
- Farrow, L., Gardner, W. T., Tang, C. C., Low, R., Forget, P. & Ashcroft, G. P. (2023). Impact of COVID-19 on opioid use in those awaiting hip and knee arthroplasty: a retrospective cohort study. BMJ Quality & Safety, 32(8), 479-484.
- Gürarslan Baş, N., Karatay, G., Bozoğlu, Ö., Akay, M., Kunduracı, E. & Aybek, H. (2016). Postoperative pain management : Nursing practices. Hacettepe Üniversitesi Hemşirelik Fakültesi Dergisi, 3(2), 40–49.
- Işıklı, A. G., Özkan, Z. K. & Buberka, Z. (2023). The Fear of Surgery and coronavirus in patients who will undergo a surgical ıntervention. Journal of Perianesthesia Nursing, 38(1), 134–138. https://doi.org/10.1016/j.jopan.2022.06.015
- Issa, Y. M., Zayed, S. I. M. & Habib, I. H. I. (2011). Simultaneous determination of ibuprofen and paracetamol using derivatives of the ratio spectra method. Arabian Journal of Chemistry, 4(3), 259–263. https://doi.org/10.1016/j.arabjc.2010.06.044
- Kumar, P., Renuka, M. K., Kalaiselvan, M. S. & Arunkumar, A. S. (2017). Outcome of noncardiac surgical patients admitted to a multidisciplinary intensive care unit. Indian Journal of Critical Care Medicine, 21(1), 17–22. https://doi.org/10.4103/0972-5229.198321
- Lavernia, C. J., Alcerro, J. C. & Rossi, M. D. (2010). Fear in arthroplasty surgery: The role of race. Clinical Orthopaedics and Related Research, 468(2), 547–554. https://doi.org/10.1007/s11999-009-1101-6
- Lim, E. J., Kim, M. & Kim, C. H. (2022). Impact of the COVID-19 pandemic on mortality following hip and knee joint arthroplasty surgeries: a systematic review and meta-analysis. Journal of personalized medicine, 12(9), 1441.
- Liu, S. S., Buvanendran, A., Rathmell, J. P., Sawhney, M., Bae, J. J., Moric, M., Perros, S., Pope, A. J., Poultsides, L., Valle, C. J. D., Shin, N. S., McCartney, C. J. L., Ma, Y., Shah, M., Wood, M. J., Manion, S. C. & Sculco, T. P. (2012). Predictors for moderate to severe acute postoperative pain after total hip and knee replacement. International Orthopaedics, 36(11), 2261–2267. https://doi.org/10.1007/s00264-012-1623-5
- Meissner, W., Mescha, S., Rothaug, J., Zwacka, S., Goettermann, A., Ulrich, K. & Schleppers, A. (2008). Qualitätsverbesserung der postoperativen schmerztherapie - Ergebnisse des QUIPS-Projekts. Deutsches Arzteblatt, 105(50), 865–870. https://doi.org/10.3238/arztebl.2008.0865
- Mete, Z. & Avcı Işık, S. (2020). Determination of the Relationship between surgical fear levels and postoperative pain levels in patients undergoing total knee prosthesis surgery. Turkiye Klinikleri Journal of Nursing Sciences, 12(3), 337–347. https://doi.org/10.5336/nurses.2019-73129
- Montalto, F., Ippolito, M., Noto, A., Madotto, F., Gelardi, F., Savatteri, P., Giarratano, … Vetrugno, L. (2021). Emotional status and fear in patients scheduled for elective surgery during COVID-19 pandemic: a nationwide cross-sectional survey (COVID-SURGERY). Journal of Anesthesia, Analgesia and Critical Care, 1(1), 1–11. https://doi.org/10.1186/s44158-021-00022-7
- Ni, C. H., Tsai, W. H., Lee, L. M., Kao, C. C. & Chen, Y. C. (2012). Minimising preoperative anxiety with music for day surgery patients - a randomised clinical trial. Journal of Clinical Nursing, 21(5–6), 620–625. https://doi.org/10.1111/j.1365-2702.2010.03466.x
- Öner, N. & Le Compte, A. (1998). Durumluk sürekli kaygı envanteri el kitabı. Boğaziçi Üniversitesi yayınevi.
- Soydan, D., Yanık, T. Ç., Uğraş, G. A. & Ayan, E. (2023). Uzayan pandemide göğüs cerrahisi geçiren hastalarda COVID-19 korkusu ve anksiyete düzeyleri. Mersin Üniversitesi Sağlık Bilimleri Dergisi, 16(3), 363-374
- Süzen, B., Kızıltan, G. & Güçlü, B. (2021). Kalça ve diz artroplastisi geçiren hastalarda proteinden zengin tıbbi beslenme tedavisinin antropometrik ölçümler ve el kavrama gücü üzerine etkisi. Başkent Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 6(Özel sayı), 131–144.
- Şahin, M. (2019). Korku, kaygı ve kaygı (anksiyete) bozuklukları. Avrasya Sosyal ve Ekonomi Araştırmaları Dergisi (ASEAD), 10(6), 117–135.
- Tulunay, M. & Tulunay, F. C. (2000). Ağrının değerlendirilmesi ve ağrı ölçümleri. In S. Erdine (Ed.), Ağrı (pp. 91–107). Nobel Tıp Kitabevleri.
- Turksal, E., Alper, I., Sergin, D., Yuksel, E. & Ulukaya, S. (2020). The effects of preoperative anxiety on anesthetic recovery and postoperative pain in patients undergoing donor nephrectomy. Brazilian Journal of Anesthesiology (English Edition), 70(3), 271–277. https://doi.org/10.1016/j.bjane.2020.06.004
- World Health Organization/WHO.Coronavirus disease (COVID-19). https://www.who.int/news-room/fact-sheets/detail/coronavirus-disease-(covid-19) Erişim tarihi: 13.June.2024
- Wu, Z. & McGoogan, J. M. (2020). Characteristics of and ımportant lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA - Journal of the American Medical Association, 323(13), 1239–1242. https://doi.org/10.1001/jama.2020.2648
THE RELATIONSHIP OF COVID-19 FEAR WITH PREOPERATIVE ANXIETY AND POSTOPERATIVE ANALGESIC REQUIREMENT IN TOTAL HIP AND KNEE ARTHROPLASTY PATIENTS
Yıl 2024,
Cilt: 12 Sayı: 3, 801 - 812, 21.10.2024
Remziye Cici
,
Ahmet Özdemir
,
Gülnaz Kızılkaya
,
Meral Özkan
Öz
It was conducted to determine the relationship between fear of Covid-19 and preoperative anxiety and postoperative analgesic requirement in total hip and knee arthroplasty patients. This descriptive study was conducted with 331 patients scheduled for arthroplasty who were hospitalized in the orthopedic clinic of a hospital in eastern Turkey between March 2022-2023. Fear of covid-19, state anxiety inventory, and visual analogue pain scale were used. The mean age of the patients was 61.9±14.4 years, 52.0% had undergone total knee arthroplasty, and there was no relationship between Covid-19 fear score and state anxiety score. A positive significant correlation was found between opioid requirement and Covid-19 fear score on the first and second days after surgery. A weak positive correlation was found between non-steroidal anti-inflammatory drug (NSAID) requirement and Covid-19 fear score on the zero, first and second days after surgery. A weak negative correlation was found between paracetamol use and Covid-19 fear score on the first and second days. It was determined that the Covid-19 fear experienced by the patients before surgery was not associated with preoperative anxiety and increased the use of analgesics such as NSAIDs and opioids after surgery.
Kaynakça
- Acar, K., Acar, H., Demir, F. & Eti Aslan, F. (2016). Cerrahi sonrası ağrı insidansı ve analjezik kullanım miktarının belirlenmesi. ACU Sağlık Bil Derg, 2, 85–91.
- Ahorsu, D. K., Lin, C. Y., Imani, V., Saffari, M., Griffiths, M. D. & Pakpour, A. H. (2020). The Fear of COVID-19 Scale: Development and ınitial validation. International Journal of Mental Health and Addiction, 20(3), 1537–1545. https://doi.org/10.1007/s11469-020-00270-8
- Arpaci, I., Karataş, K. & Baloğlu, M. (2020). The development and initial tests for the psychometric properties of the COVID-19 Phobia Scale (C19P-S). Personality and Individual Differences, 164(April), 110108. https://doi.org/10.1016/j.paid.2020.110108
- Aşcı, M. (2019). Total di̇z artroplasti̇si̇nde korku ve anksi̇yeteni̇n yaşam kali̇tesi ve ı̇şlevsel sonuçlara etki̇si̇. Bozok Tıp Dergisi, 100, 139–143. https://doi.org/10.16919/bozoktip.528492
- Ay, F. & Alpar, S. E. (2010). Postoperatif ağrı ve hemşirelik uygulamaları. Ağrı, 22(1), 21–29. http://www.ncbi.nlm.nih.gov/pubmed/20209411
- Aydınak, S., Yalçın, C. Ö. & Abudayyak, M. (2018). Psychiatric adverse effects of non-steroidal analgesic anti-inflammatory drugs. Journal of Literature Pharmacy Sciences, 7(1), 61–72. https://doi.org/10.5336/pharmsci.2017-58076
- Bakioğlu, F., Korkmaz, O. & Ercan, H. (2021). Fear of COVID-19 and positivity: Mediating role of ıntolerance of uncertainty, depression, anxiety, and stress. International Journal of Mental Health and Addiction, 19, 2369–2382. https://doi.org/https://doi.org/10.1007/s11469-020-00331-y
- Balkaya, A. N., Karaca, Ü., Yılmaz, C. & Ata, F. (2021). COVID-19 pandemisinde elektif cerrahi uygulanacak hastaların preoperatif anksiyete düzeylerinin değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 47(2), 233-239).
- Baskan, S., Oken, F., Kılcı, O., Dılek, K., Tırın, H., Yıldırım, O., Incı, F. & Ornek, D.(2020).Comparison of adductor canal block and local infi ltration analgesia techniques for postoperative analgesia in gonarthrosis patients receiving a total knee prosthesis. Turk J Clin Lab, 11(2), 6-11.
- Brown, T.S., Bedard, N.A., Roja, E.O., Anthony, C.A., Schwarzkopf, R., Barnes, C.L., Stambough, J.B., Mears,S.C., Edwards, P.K., Nandi, S., Prieto, H.A., Parvizi,J. (2020). The Effect of the COVID-19 Pandemic on Electively Scheduled Hip and Knee Arthroplasty Patients in the United States. J Arthroplasty. Jul, 35(7S):S49-S55. doi: 10.1016/j.arth.2020.04.052.
- Dagli, R., Avcu, M., Metin, M., Kiymaz, S. & Ciftci, H. (2019). The effects of aromatherapy using rose oil (Rosa damascena Mill.) on preoperative anxiety: A prospective randomized clinical trial. European Journal of Integrative Medicine, 26(November 2018), 37–42. https://doi.org/10.1016/j.eujim.2019.01.006
- Demir, S. G. & Erdil, F. (2013). Effectiveness of home monitoring according to the Model of Living in hip replacement surgery patients. Journal of Clinical Nursing, 22(9–10), 1226–1241. https://doi.org/10.1111/jocn.12255
- Doğan, R., Kaplan Serin, E. & Bağcı, N. (2021). Fear of COVID 19 and social effects in liver transplant patients. Transplant Immunology, 69(October). https://doi.org/10.1016/j.trim.2021.101479
- Duivenvoorden, T., Vissers, M. M., Verhaar, J. A. N., Busschbach, J. J. V., Gosens, T., Bloem, R. M., Bierma-Zeinstra, S. M. A. & Reijman, M. (2013). Anxiety and depressive symptoms before and after total hip and knee arthroplasty: A prospective multicentre study. Osteoarthritis and Cartilage, 21(12), 1834–1840. https://doi.org/10.1016/j.joca.2013.08.022
- Ennis, Z. N., Dideriksen, D., Vægter, H. B., Handberg, G. & Pottegård, A. (2016). Acetaminophen for chronic pain: A Systematic review on efficacy. Basic and Clinical Pharmacology and Toxicology, 118(3), 184–189. https://doi.org/10.1111/bcpt.12527
- Erlenwein, J., Müller, M., Falla, D., Przemeck, M., Pfingsten, M., Budde, S., Quintel, M. & Petzke, F. (2017). Clinical relevance of persistent postoperative pain after total hip replacement – a prospective observational cohort study. J Pain Res, 10, 2183–2193. https://doi.org/https://doi.org/10.2147/JPR.S137892
- Farrow, L., Gardner, W. T., Tang, C. C., Low, R., Forget, P. & Ashcroft, G. P. (2023). Impact of COVID-19 on opioid use in those awaiting hip and knee arthroplasty: a retrospective cohort study. BMJ Quality & Safety, 32(8), 479-484.
- Gürarslan Baş, N., Karatay, G., Bozoğlu, Ö., Akay, M., Kunduracı, E. & Aybek, H. (2016). Postoperative pain management : Nursing practices. Hacettepe Üniversitesi Hemşirelik Fakültesi Dergisi, 3(2), 40–49.
- Işıklı, A. G., Özkan, Z. K. & Buberka, Z. (2023). The Fear of Surgery and coronavirus in patients who will undergo a surgical ıntervention. Journal of Perianesthesia Nursing, 38(1), 134–138. https://doi.org/10.1016/j.jopan.2022.06.015
- Issa, Y. M., Zayed, S. I. M. & Habib, I. H. I. (2011). Simultaneous determination of ibuprofen and paracetamol using derivatives of the ratio spectra method. Arabian Journal of Chemistry, 4(3), 259–263. https://doi.org/10.1016/j.arabjc.2010.06.044
- Kumar, P., Renuka, M. K., Kalaiselvan, M. S. & Arunkumar, A. S. (2017). Outcome of noncardiac surgical patients admitted to a multidisciplinary intensive care unit. Indian Journal of Critical Care Medicine, 21(1), 17–22. https://doi.org/10.4103/0972-5229.198321
- Lavernia, C. J., Alcerro, J. C. & Rossi, M. D. (2010). Fear in arthroplasty surgery: The role of race. Clinical Orthopaedics and Related Research, 468(2), 547–554. https://doi.org/10.1007/s11999-009-1101-6
- Lim, E. J., Kim, M. & Kim, C. H. (2022). Impact of the COVID-19 pandemic on mortality following hip and knee joint arthroplasty surgeries: a systematic review and meta-analysis. Journal of personalized medicine, 12(9), 1441.
- Liu, S. S., Buvanendran, A., Rathmell, J. P., Sawhney, M., Bae, J. J., Moric, M., Perros, S., Pope, A. J., Poultsides, L., Valle, C. J. D., Shin, N. S., McCartney, C. J. L., Ma, Y., Shah, M., Wood, M. J., Manion, S. C. & Sculco, T. P. (2012). Predictors for moderate to severe acute postoperative pain after total hip and knee replacement. International Orthopaedics, 36(11), 2261–2267. https://doi.org/10.1007/s00264-012-1623-5
- Meissner, W., Mescha, S., Rothaug, J., Zwacka, S., Goettermann, A., Ulrich, K. & Schleppers, A. (2008). Qualitätsverbesserung der postoperativen schmerztherapie - Ergebnisse des QUIPS-Projekts. Deutsches Arzteblatt, 105(50), 865–870. https://doi.org/10.3238/arztebl.2008.0865
- Mete, Z. & Avcı Işık, S. (2020). Determination of the Relationship between surgical fear levels and postoperative pain levels in patients undergoing total knee prosthesis surgery. Turkiye Klinikleri Journal of Nursing Sciences, 12(3), 337–347. https://doi.org/10.5336/nurses.2019-73129
- Montalto, F., Ippolito, M., Noto, A., Madotto, F., Gelardi, F., Savatteri, P., Giarratano, … Vetrugno, L. (2021). Emotional status and fear in patients scheduled for elective surgery during COVID-19 pandemic: a nationwide cross-sectional survey (COVID-SURGERY). Journal of Anesthesia, Analgesia and Critical Care, 1(1), 1–11. https://doi.org/10.1186/s44158-021-00022-7
- Ni, C. H., Tsai, W. H., Lee, L. M., Kao, C. C. & Chen, Y. C. (2012). Minimising preoperative anxiety with music for day surgery patients - a randomised clinical trial. Journal of Clinical Nursing, 21(5–6), 620–625. https://doi.org/10.1111/j.1365-2702.2010.03466.x
- Öner, N. & Le Compte, A. (1998). Durumluk sürekli kaygı envanteri el kitabı. Boğaziçi Üniversitesi yayınevi.
- Soydan, D., Yanık, T. Ç., Uğraş, G. A. & Ayan, E. (2023). Uzayan pandemide göğüs cerrahisi geçiren hastalarda COVID-19 korkusu ve anksiyete düzeyleri. Mersin Üniversitesi Sağlık Bilimleri Dergisi, 16(3), 363-374
- Süzen, B., Kızıltan, G. & Güçlü, B. (2021). Kalça ve diz artroplastisi geçiren hastalarda proteinden zengin tıbbi beslenme tedavisinin antropometrik ölçümler ve el kavrama gücü üzerine etkisi. Başkent Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 6(Özel sayı), 131–144.
- Şahin, M. (2019). Korku, kaygı ve kaygı (anksiyete) bozuklukları. Avrasya Sosyal ve Ekonomi Araştırmaları Dergisi (ASEAD), 10(6), 117–135.
- Tulunay, M. & Tulunay, F. C. (2000). Ağrının değerlendirilmesi ve ağrı ölçümleri. In S. Erdine (Ed.), Ağrı (pp. 91–107). Nobel Tıp Kitabevleri.
- Turksal, E., Alper, I., Sergin, D., Yuksel, E. & Ulukaya, S. (2020). The effects of preoperative anxiety on anesthetic recovery and postoperative pain in patients undergoing donor nephrectomy. Brazilian Journal of Anesthesiology (English Edition), 70(3), 271–277. https://doi.org/10.1016/j.bjane.2020.06.004
- World Health Organization/WHO.Coronavirus disease (COVID-19). https://www.who.int/news-room/fact-sheets/detail/coronavirus-disease-(covid-19) Erişim tarihi: 13.June.2024
- Wu, Z. & McGoogan, J. M. (2020). Characteristics of and ımportant lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA - Journal of the American Medical Association, 323(13), 1239–1242. https://doi.org/10.1001/jama.2020.2648