MALİGN LENFOMA VE KRONİK İNFLAMATUAR DEMİYELİNİZAN POLİNÖROPATİ: BİR OLGU SUNUMU

Yıl 2006, Cilt: 69 Sayı: 1, 19 - 22, 15.11.2011

Murat Kürtüncü Nihal Işık Piraye Serdaroğlu Feza Deymeer Yeşim Parman Arzu Çoban Arzu Çoban

https://izlik.org/JA28WW89GB

Öz

Non-Hodgkin malign lenfomalar (NHML), B ya da T hücreli malign lenfoid proliferasyon ile karakterizedir. NHML seyrinde periferik sinir tutulumu Hodgkin hastalığına göre daha nadirdir. Bu yazıda, B hücreli non-Hodgkin malign lenfoması ile kronik inflamatuvar demiyelinizan polinöropatisi olan ve kanda paraproteinemi saptanmayan bir olgu sunulmaktadır; non-Hodgkin malign lenfomanın seyri sırasındaki periferik nöropatilerin çeşitli oluş mekanizmaları tartışılmıştır.

Anahtar Kelimeler

Non-Hodgkin malign lenfoma , polinöropati , paraproteinemi

Kaynakça

• Ad Hoc Subcommittee of the American Academy of Neurology AIDS Task Force. Research criteria for diagnosis of chronic inf- lammatory demyelinating polyradiculoneuropathy (CIDP). Ne- urology 1991; 41:617-618.
• Andreoli TE, Bennett JC, Carpenter CJ, Plum F, Smith LH. He- matological Malignant Diseases. In: Cecil Essentials Of Medici- ne. W.B. Saunders Company, 3rd ed., 1995; pp 393-397.
• Bromberg MB, Feldman EL, Albers JW. Chronic inflammatory demyelinating polyradiculoneuropathy: comparison of patients with and without an associated monoclonal gammopathy. Ne- urology 1992; 42:1157-1163.
• Eurelings M, Notermans NC, Van de Donk NW, Lokhorst HM. Risk factors for hematological malignancy in polyneuropathy associated with monoclonal gammopathy. Muscle Nerve 2001; 24:1295-1302.
• Gorson KC, Allam G, Ropper AH. Chronic inflammatory dem- yelinating polyneuropathy: clinical features and response to tre- atment in 67 consecutive patients with and without a monoclo- nal gammopathy. Neurology 1997; 48:321-328.
• Henson RA, Urich H. Peripheral neuropathy associated with malignant neoplasms. In: Henson RA, Urich H. Cancer and the nervous system. Oxford: Blackwell Scientific. 1982; pp 368- 405.
• Johnson PC, Rolak LA, Hamilton RH, Laguna F. Paraneoplastic vasculitis of nerve: a remote effect of cancer. Ann Neurol 1979; 5:437-444.
• Kuroda Y, Nakata H, Kakigi R, Oda K, Shibasaki H, Nakashiro H. Human neurolymphomatosis by adult T-cell leukemia. Ne- urology 1989;39:144-146.
• Lisak RP, Mitchell M, Zweiman B, Orrechio E, Asbury AK. Gu- illain-Barre syndrome and Hodgkin’s disease: three cases with immunological studies. Ann Neurol 1977; 1:72-78.
• Mc Leod JG. Peripheral neuropathy associated with lympho- mas, leukemias, and polycythemia vera. In: Peripheral Neuro- pathy. W.B. Saunders Company, 3rd ed., volume 2,1993; pp 1591-1598.
• Monaco S, Bonetti B, Ferrari S, Moretto G, Nardelli E, Tedesco F, et al. Complement-mediated demyelination in patients with IgM monoclonal gammopathy and polyneuropathy. N Engl J Med 1990; 322:649-652.
• Öge AE, Parman Y. Polinöropatiler. A.E. Öge (ed); Nöroloji, İs- tanbul, Nobel Tıp Kitabevleri; 2004; ss. 591-625.
• Said G. Chronic inflammatory demyelinative polyneuropathy. J Neurol 2002; 249:245-253.
• Sumi SM, Farrell DF, Knauss TA. Lymphoma and leukemia ma- nifested by steroid-responsive polyneuropathy. Arch Neurol 1983; 40:577-582.
• Vallat JM, De Mascarel HA, Bordessoule D, Jauberteau MO, Tabaraud F, Gelot A, Vallat AV. Non-Hodgkin malignant lymphomas and peripheral neuropathies 13 cases. Brain 1995; 118:1233-1245.
• Vallat JM, Leboutet MJ, Hugon J, Tabaraud F, Chartier JP, Bo- ulesteix JM. Demyelinating polyneuropathy associated with cancer-a nerve biopsy study of eight cases. Clin Neuropathol 1988; 7:217.
• Vital A. Paraproteinemic neuropathies. Brain Pathol 2001; 11:399-407.
• Vital C, Vital A, Julien J, Rivel J, de Mascarel A, Vergier B, et al. Peripheral neuropathies and lymphoma without monoclonal gammopathy: a new classification. J Neurol 1990; 237:177-185.