INTRACRANIAL HEMANGIOPERICYTOMA: A CASE REPORT

Öz

Meningeal hemangiopericytoma (HPC) originating from pericytes is a highly vascularised and a  rare mesenchimal tumor that constitutes %0.4 of all primary central nervous system tumors . These tumors share common arachnoid location with benign meningioma and mimic meningiomas in clinical and radiographic presentation. Because of the aggressive nature of the central nervous system HPs with high recurrence and distal metastasis rates the first line treatment is total resection with close follow ups postoperatively. In this report we tried to analyse the differentiation of hematoma and recurrence and evaluated the role of radiotherapy in light of the current literature.

Anahtar Kelimeler

• hematoma
• intracranial hemangiopericytoma
• treatment

İNTRAKRANYAL HEMANJİOPERİSİTOMA: BİR OLGU SUNUMU

Öz

Meningial hemanjioperisitoma (HP) primer merkezi sinir sistemi tümörlerinin 0,4 % ünü oluşturan nadir ve oldukça vasküler bir mezenkimal tümördür. Hemanjioperisitomalar benign meningiomlarla ortak araknoid lokasyonlari kullanırlar, klinik ve radyolojik olarak onları taklit ederler. Perisitlerden kaynaklanan bu tümörlerde total rezeksiyon ilk tedavi seçeneği olup merkezi sinir sistemi HP larının agresif biolojisi nedeni ile rekurrens ve uzak metastaz ihtimali de göz önünde bulundurularak ameliyat sonrası yakın takibi çok önem taşır. Bu yazıda HP larda postop dönemde ortaya çıkabilen komplikasyonlardan olan rekurrens ve hematomun ayırt ettirici özelliklerinin vurgulanması ve radyoterapinin yeri konusunda son literatür bilgilerinin gözden geçirilmesi amaçlanmıştır.

Anahtar Kelimeler

• hematom
• intrakranyal hemanjioperisitoma
• tedavi

Kaynakça

1. Chiechi MV, Smirniotopoulos JG, Mena H. Intracranial Hemangiopericytomas: MR and CT Features. Am J Neuroradiol 1996;17:1365–1371. Fredriksson F, Nordborg C, Hallén T, Blomquist E. Haemangiopericytoma presenting with acute intracerebral haemorrhage-a case report and literature review. Acta Oncol 2013;52(4):753-758. Goellner JR, Laws ER, Soule EH, Okazaki H. Hemangiopericytoma of the meninges: Mayo Clinic experience. Am J Clin Pathol 1978;70:375–380.
2. Jaaskelainen J, Servo A, Haltia M, Wahlstrom T, Valtonen S. Intracranial hemangiopericytoma: radiology, surgery, radiotherapy, and outcome in 21 patients. Surg Neurol 1985;23:227–236.
3. Louis DN, Wiestler OD, Cavenee WK, eds. WHO Classification of Tumours of the Central Nervous System. Lyon, France: IARC Press; 2007;178-180. Mena H, Ribas JL, Pezeshkpour GH, Cowan DN, Parisi JE. Hemangiopericytoma of the central nervous system: a review of 94 cases. Hum Pathol 1991;22:84–89.
4. Rutkowski MJ, Jian BJ, Bloch O, Chen C, Sughrue ME, Tihan T,et al. Intracranial hemangiopericytoma: clinical experience and treatment considerations in a modern series of 40 adult patients. Cancer 2012; 15;118(6):1628-1636.
5. Rutkowski MJ, Sughrue ME, Kane AJ, Aranda D,Mills SA, Barani IJ, et al. Predictors of mortality following treatment of intracranial hemangiopericytoma. J Neurosurg 2010;113:3333
6. Schiariti M, Goetz P, El-Maghraby H, Tailor J, Kitchen N: Hemangiopericytoma: long-term outcome revisited. Clinical article. J Neurosurg 2010;114:747–755.