Sistemik Lupus Eritematozuslu 126 Gebenin Perinatal Sonuçları

Yıl 2018, Cilt: 81 Sayı: 2, 51 - 55, 29.05.2018

Ayşegül Özel Ebru Alıcı Davutoğlu Hakan Erenel Mehmet Fatih Karslı Sevim Özge Korkmaz Rıza Madazlı

Öz

DOI: 10.26650/IUITFD.344912

Amaç: Sistemik lupus eritematozus (SLE)
tanısı almış ve gebe olan olguların maternal ve perinatal sonuçlarının
değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntem: Çalışmamız 2002-2016
yılları arasında üniversitemizin perinataloji kliniğinde gebelikleri takip
edilmiş 126 SLE olgusunun dosya verilerinin retrospektif olarak incelenmesiyle
yapıldı. Hastaların klinik karakteristikleri, obstetrik ve perinatal sonuçları
değerlendirildi.

Bulgular: Hastaların ortalama yaşı 29,1±
4,6 yıl ve nulliparite oranı %45,2 idi. Gebelik sırasında hastalığın
alevlenmesi hastaların %11,1’ inde görüldü. Lupus antikoagulanı,
antikardiyolipin IgG ve IgM antikorlarının pozitifliği sırasıyla; %23,8 , %18,2
ve  %18,2 olarak saptandı. Ortalama doğum
haftası 37,2±3,7, ortalama doğum kilosu 2813 ±856 gr bulundu. Fetal büyüme
kısıtlılığı, preterm doğum, ölü doğum, preeklampsi görülme oranları sırasıyla;
%16,6 , %10,3 , %10,3 , %9,5 olarak bulundu.

Sonuç: SLE tanılı gebelik olgularının
yönetiminde multidisipliner yaklaşım ile takip ve tedavinin sağlanması olumlu
maternal ve fetal sonuçlar ile ilişkilidir.

Anahtar Kelimeler

Sistemik lupus eritematozus, perinatal, maternal, gebelik

Perinatal Outcomes Of 126 Pregnancies With Sistemic Lupus Erythematosus

Öz

DOI: 10.26650/IUITFD.344912

Objective: To evaluate maternal and fetal
outcomes in pregnant women with systemic lupus erythematosus (SLE).

Materials and Methods: This retrospective
clinical study included 126 consecutive cases of pregnant women with SLE and
was performed in the perinatology clinic of our university hospital. We
evaluated lupus pregnancies that were followed and delivered from 2002 to 2016.

Results: The mean patient age was 29.1 ±
4.6 years, and the nulliparity rate was 45.2%. Disease flare-up occurred in
11.1% of patients. Lupus anticoagulants and anticardiolipin IgG and IgM
antibodies were positive in 23.8%, 18.2%, and 18.2% patients, respectively. The
mean gestational age at delivery was 37.2 ± 3.7, and the mean birth weight was
2813 ± 856 g. Fetal growth restriction, preterm delivery, stillbirth, and
preeclampsia rates were 16.6%, 10.3%, 10.3%, and 9.5%, respectively.

Conclusion:
A multidisciplinary approach to the care of pregnant women with SLE is
mandatory for good maternal and fetal outcomes.

Anahtar Kelimeler

Systemic lupus erythematosus, perinatal, maternal, pregnancy

Kaynakça

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