İLK BULGUSU HİPONATREMİ OLAN AKCİĞERİN KÜÇÜK HÜCRELİ KARSİNOMU: OLGU SUNUMU

Yıl 2020, Cilt: 83 Sayı: 4, 451 - 453, 19.10.2020

Emel Bayrak Kayser Çağlar

Öz

Hipertansiyon ve diyabetes mellitus tanıları olan altmış iki yaşındaki kadın hasta; halsizlik, uykusuzluk, dengesizlik ve baş ağrısı yakınmaları ile acil servise başvurdu. Yapılan tetkiklerinde ciddi hiponatremi saptanan ve hastaneye yatırılan hasta hiponatremiye yol açabilecek ilaçları kesilerek takip edildi. Hiponatremisi devam eden hastada yapılan incelemelerde uygunsuz antidiüretik hormon (ADH) sendromu saptanarak çekilen torax tomografisinde akciğerde kitle tespit edildi ve histopatolojik inceleme akciğerin küçük hücreli karsinomu olarak rapor edildi.

Anahtar Kelimeler

Hiponatremi, uygunsuz ADH sendromu, akciğer kanseri

HYPONATREMIA AS A FIRST SIGN OF SMALL CELL LUNG CANCER: A CASE REPORT

Öz

A 62-year- old woman with a history of hypertension and diabetes mellitus was admitted to the emergency department because of headache, weakness, insomnia and impaired balance. Severe hyponatremia was detected and patient was admitted to the hospital. The drugs that could lead to hyponatremia were stopped. Additional investigations were made because of the persistence of hyponatremia. After the diagnosis of inappropriate ADH syndrome computed tomography of the chest was performed which revealed a pulmonary mass. The histopathological test revealed small-cell carcinoma of the lung.

Anahtar Kelimeler

Hyponatremia, inappropriate ADH syndrome, lung neoplasms

Kaynakça

• 1. Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, et al.; on behalf of the Hyponatraemia Guideline Development Group. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Nephrol Dial Transplant 2014:29(Suppl.2):ii1-ii39.
• 2. Sterns RH, Diagnostic evaluation of adults with hyponatremia. In: UpToDate, Emmett M(Ed), UpToDate, Waltham, MA. (Accessed on July 19, 2019.)
• 3. Rawal G, Kumar R, Yadav S. Severe hyponatremia associated with escitalopram, J Family Med Prim Care 2017;6(2):453-4.
• 4. Kitchlu A, Rosner M Hyponatremia in patients with cancer. Current Opinion in Nephrology and Hypertension 2019;8(5):433-40.
• 5. Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008;83(5):584-94.