AİLESEL AKDENİZ ATEŞİ'NDE BÖBREK TUTULUMU

Yıl 2009, Cilt: 72 Sayı: 2, 71 - 74, 11.11.2011

Sema Yılmaz

Öz

Ailesel Akdeniz Ateşi (AAA), otozomal resesif geçiş gösteren, tekrarlayan ateş, peritonit, plörit ve sinovit atakları ile karakterize kalıtımsal bir hastalıktır. AAA’nin en önemli özelliğinden birisi sistemik amiloidoz ve amiloidoz dışı diğer böbrek patolojilerine neden olmasıdır. AAA ile ilişkili amiloidoz, başlangıçta proteinüri ile kendini gösterir, nefrotik sendrom ve böbrek yetmezliğine kadar ilerleyebilir. Son 30 yılda hastalığa erken tanı koymak ve kolşisinle erken tedaviye başlamakla, AAA ile ilişkili amiloidoz insidansı giderek azalmıştır.

Anahtar Kelimeler

Ailesel akdeniz ateşi, böbrek

Kaynakça

• Akar N, Hasipek M, Akar E. Serum amyloid A1 and tumor nec- rosis factor-alpha alleles in Turkish familial Mediterranean fever patients with and without amyloidosis. Amyloid 2003; 10:12-16.
• Ben-Chetrit E, Levy M. Familial Mediterranean Fever. Lancet 1998; 351: 659-667.
• Ben-Chetrit E. Familial Mediterranean Fever (FMF) and renal AA amyloidosis-phenotype-genotype correlations, treatment and prognosis. J Nephrol 2003; 16: 431-438.
• Ben-Cheritt E, Backenroth R. Amyloidosis induced, end stage re- nal diseasein patients with familial Mediterranean fever is highly associated with point mutations in the MEFV gene. Ann Rheum Dis 2001; 60: 146-149.
• Blum A, Sohar E. The diagnosis of amyloidosis.Ancillary proce- dures. Lancet 1962; 1: 721-724.
• Brik R, Shinawi M, Kepten I. Familial Mediterranean fever: cli- nical and genetic characterization in a mixed pediatric population of Jewish and Arab patients. Pediatrics 1999; 103: 70-76.
• Cazeneuve C, Sarkisian T, Pecheux C. MEFV-gene analysis in Armenian patients with Familial Mediterranean fever: diagnostic value and unfavorable renal prognosis of the M694V homozygo- us genotype-genetic and therapeutic implications. Am J Hum Ge- net 1999; 65:88-97.
• Dagan T, Danon Y, Lotan R. Phenotype-genotype in FMF: Fami- lial Mediterranean Fever. The official book of 1 st International Conference on FMF, September 1997; 239-245.
• Duzova A, Bakkaloglu A, Besbas N. Role of A-SAA in monito- ring subclinical inflammation and in colchicine dosage in famili- al Mediterranean fever. Clin Exp Rheumatol 2003; 21: 509-514.
• Gershoni-Baruch R, Brik R, Shinawi M. The differential contri- bution of MEFV mutant alleles to the clinical profile of familial Mediterranean fever. Eur J Hum Genet 2002; 10: 145-149.
• Gershoni-Baruch R, Brik R, Zacks N. The contribution of ge- notypes at the MEFV and SAA1 loci to amyloidosis and disease severity in patients with familial Mediterranean fever. Arthritis Rheum 2003; 48: 1149-1155.
• Goldfinger SE. Colchicine for familial Mediterranean fever. N Engl J Med 1972; 287: 1302.
• Korkmaz C, Ozdogan H, Kasapcopur O. Acute phase response in familial Mediterranean fever. Ann Rheum Dis 2002; 61:79-81.
• Lidar M, Yaqubov M, Zaks N. The prodrome: a prominent yet overlooked pre-attack manifestation of familial Mediterranean fever. J Rheumatol 2006; 33: 1089-1094.
• Livneh A, Shtrasburg S, Langevitz P. Regression of nephrotic syndrome in amyloidosis of familial Mediterranean fever follo- wing colchicine treatment. Nephrol Dial Transplant 2000; 15:1713-1714.
• Majeed HA, El-Shanti H, Al-Khateeb MS. Genotype/phenotype correlations in Arab patients with familial Mediterranean fever. Semin Arthritis Rheum 2002; 31:371-376.
• Mansour I, Delague V, Cazeneuve C. Familial Meditarranean fe- ver in Lebanon: mutation spectrum, evidence cases in Maronites, Greek Orthodoxes, Greek Catholics, Syriacs and Chiites and for an association between amyloidosis and M694V and M691 mu- tations. Eur J Hum Genet 2001; 9: 51-55.
• Minetti EE, Minetti L. Multiple organ failure in a kidney transp- lant patient receiving both colchine and cyclosporine. J Nephrol 2003; 16: 421-425.
• Ozdogan H, Arısoy N, Kasapcapur O, Sever L, Calıskan S, Tu- zuner N, Mat C, Yazıcı H. Vasculitis in familial Mediterranean fe- ver. J Rheumatol 1997; 24: 323-327.
• Ozen S, Karaaslan Y, Ozdemir O. Prevalance of juvenile chronic arthritis and familial Mediterranean fever in Turkey: a field study. J Rheumatol 1998; 25: 2445-2449.
• Pras E, Aksentijevich I, Gruberg L. Maping of a gene causing fa- milial Mediterranean fever to the short of chromosome 16. N Engl J Med 1992; 326: 1507-1509.
• Pras E, Livneh A, Balow JE. Clinical differences between north African and Iraqi Jews with familial Mediterranean fever. Am J Med Genet 1998; 75: 216-219.
• Rubinger D, Friedlaender MM, Popovtzer MM. Amelioration of familial Mediterranean fever during hemodialysis. N Engl J Med 1979; 301: 142-144.
• Saatcı U, Ozen S, Ozdemir S, Bakkaloglu A, Besbas N, Topalog- lu R, Arslan S. Familial Mediterranean fever in children: report of a large series and discussion of the risk and prognostic factors of amyloidosis. Eur J Pediatr 1997; 156: 619-623.
• Said R, Hamzeh Y, Tarawneh M, el-Khateeb M, Abdeen M, Sha- heen A. Rapid progressive glomerulonephritis in patients with fa- milial Mediterranean fever. Am J Kidney Dis 1989; 14: 412-416.
• Shonat M, Danon YL, Rotter JI. Familial Mediterranean fever: Analysis of inheritance and current linkage data. Am J Med Ge- net 1992; 44: 183-188.
• Shonat M, Livneeh A, Zemer D. Twin studies in familial Medi- terranean fever. Am J Med Genet 1992; 44: 179-186.
• Sidi G, Shinar Y, Livneh A. Protracted febrile myalgia of famili- al Mediterranean fever. Mutation analysis and clinical correlati- ons. Scand J Rheumatol 2000; 29: 174-176.
• Sohar E, Gafni J, Pras M. Familial Mediterranean fever a survey of 470 cases and review of the literature. Am J Med 1967; 43: 227-253.
• Tekin M, Yalcınkaya F, Cakar N. MEFV mutations in multiplex families with familial Mediterranean fever. is a particular genoty- pe necessary for amyloidosis? Clin Genet 2000; 57: 430-434.
• Tekin M, Yalcınkaya F, Tumer N, Cakar N, Kocak H, Ozkaya N, Gencgonul H. Familial Mediterranean fever- renal involvement by diseases other than amyloid. Nephrol Dial Transplant 1999; 14: 475-479.
• The International FMF Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause fa- milial Mediterranean fever. Cell 1997; 90: 797-807.
• The French FMF Consortium. A candidate gene for familial Me- diterranean fever. Nat Genet 1997; 17: 25-31.
• Tidow N, Chen X, Muller C. Hematopoietic- specific expression of MEFV, the gene mutated in familial Mediterranean fever, and subcellular localization of its corresponding protein, pyrin. Blood 2000; 95: 1451-1459.
• Tishler M, Pras M, Yaron M. Abdominal fat tissue aspirate in amyloidosis of familial Mediterranean fever. Clin Exp Rheuma- tol 1988; 6: 395-397.
• Touitou I, Picot M-C, Domingo C. The MICA region determines the first modifier locus in familial Mediterranean fever. Arthritis Rheum 2001; 44: 163-169.
• Turkmen A, Yıldız A, Erkoc R. Transplantation in renal amylo- idosis. Clin Transplant 1998; 12: 375-378.
• Yalcınkaya F, Tekin M, Cakar N. Familial Mediterranean fever and systemic amyloidosis in untreated Turkish patients. Q J Med 2000; 93: 681-684.
• Yalcınkaya F, Tumer N. Glomerular lesions other than amyloido- sis in patients with familial Mediterranean fever. Nephrol Dial Transplant 1999; 14: 21-23.
• Yıldız A, Akkaya V, Kılıcaslan R. Cardiac and intestinal amylo- idosis in a renal transplant recipient with familial Mediterranean fever. J Nephrol 2001; 14: 125-127.
• Zemer D, Livneh A, Danon YL, Pras M, Sohar E. Long-term colchicine treatment in children with familial Mediterranean fe- ver. Arthritis Rheum 1991; 34: 973-977.
• Zemer D, Pras M, Sohar E. Colchicine in the prevention and tre- atment of the amyloidosis of familial Mediterranean fever. N Engl J Med 1986; 314: 2001-2005.