Migren Hastalarında Olası Tetikleyici Beslenme Faktörlerinin Değişimli Diyet Modeliyle Saptanması

Yıl 2024, , 70 - 76, 21.06.2024

Mustafa Emrecan Uludağ , Nihat Şengeze , Özge Türk , Adnan Karaibrahimoğlu

https://doi.org/10.57221/izmirtip.1308037

Öz

Amaç: Bu çalışmanın amacı, hastalara peynir, kafein ve çikolatadan kısıtlı diyet programları uygulayarak, diyet programlarının migrenin şiddeti, süresi ve atak sayısı üzerine etkisini belirlemektir.

Gerekçe ve Yöntemler: Çalışmaya alınan migren hastalarına üç farklı (çikolatasız, peynirsiz, kafeinsiz) beslenme önerisiyle beraber migren ataklarını kaydedebilecekleri bir çizelge verildi. Bu 3 diyet önerisi her biri ikişer hafta olmak üzere toplamda 6 hafta ayrı ayrı uygulandı. Hastaların diyet programları esnasında doldurduğu çizelge, toplam 6 hafta sonunda yüz yüze görüşmeyle toplandı.

Bulgular: Çalışma, peynir, kafein ve çikolatadan kısıtlı diyet döneminde migren ataklarının süresi, şiddeti ve sayısında azalma tespit etti. Kafeinsiz diyet esnasında oluşan atak sayısındaki azalma dışında tüm düşüşler istatistiksel olarak anlamlıdır.

Sonuç: Bu çalışma, migren hastalarının yönetiminde peynirsiz, çikolatasız veya kafeinsiz bir diyet kullanmanın yaşam kalitesini artırabileceğini ve ilaç tedavisine olan ihtiyacı azaltabileceğini göstermektedir.

Anahtar Kelimeler

Kafein, Çikolata, Migren, Peynir, Migren Tetikleyicileri

Destekleyen Kurum

Süleyman Demirel Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi Lisans Katılımlı Öğrenci Desteği

Proje Numarası

TLP-2022-8589

Detection of Possible Trigger Nutrition Factors in Migraine Patients with Alternating Diet Model

Öz

Aim: The aim of this study is to determine the effects of diet programs on the severity and duration of migraines and the number of attacks by administering cheese, caffeine, and chocolate-restricted diet programs to patients.

Material and Methods: The migraine patients included in the study were given three different (chocolate-free, cheese-free, caffeine-free) dietary recommendations and were given a chart in which they could record their migraine attacks. The dietary recommendations were administered separately every two weeks. The chart filled out by the patients was collected through face-to-face interviews at the end of the total 6 weeks.

Results: The study determined a decrease in the duration, severity, and number of migraine attacks in the period of a diet free from cheese, caffeine, and chocolate. Except for the decrease in the number of attacks on the caffeine-free diet, all the decreases are statistically significant.

Conclusion: This study shows that using a cheese-free, chocolate-free, or caffeine-free diet in managing migraine patients may improve the quality of life, and the need for drug treatment may decrease.

Anahtar Kelimeler

Caffeine, Migraine, Cheese, Chocolate, Migraine Triggers

Proje Numarası

TLP-2022-8589

Kaynakça

• 1. Headache Classification Committee of the International Headache Society (IHS). The İnternational classification of headache disorders. Cephalalgia. 2018;38:1-211.
• 2. Rossi MF, Tumminello A, Marconi M, Gualano MR, Santoro PE, Malorni W, et al. Sex and gender differences in migraines: A narrative review. Neurol Sci.2022;43:5729-34.
• 3. Lipton RB, Bigal ME, Diamond M, Freitag F, Reed ML, Stewart WF, et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology.2007;68:343-49.
• 4. GBD 2016 Headache Collaborators. Global, regional, and national burden of migraine and tension-type headache, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2018;17:954-76.
• 5. Fukui PT, Gonçalves TRT, Strabelli CG, Lucchino NMFL, Matos FCi, Santos JPM et al. Trigger factors in migraine patients. Arq Neuro-Psiquiatr. 2008;66:494-9.
• 6. Mollaoğlu M. Trigger factors in migraine patients. J Health Psychol. 2013;18:984-94.
• 7. Lipton RB, Pavlovic JM, Haut SR, Grosberg BM, Buse DC. Methodological issues in studying trigger factors and premonitory features of migraine. Headache. 2014;54:1661-9.
• 8. Marmura MJ. Triggers, protectors, and predictors in episodic migraine. Curr Pain Headache Rep. 2018;22:81. 9. Pavlovic JM, Buse DC, Sollars CM, Haut S, Lipton RB. Trigger factors and premonitory features of migraine attacks: summary of studies. Headache. 2014;54:1670-9.
• 10. Blau JN. Migraine triggers: practice and theory. Pathol Biol. 1992;40:367-72.
• 11. Rockett FC, de Oliveira VR, Castro K, Chaves MLF, Perla A da S, Perry IDS. Dietary aspects of migraine trigger factors. Nutr Rev. 2012;70:337-56.
• 12. Razeghi JS, Ghorbani Z, Martelletti P, Lampl C, Togha M. School of Advanced Studies of the European Headache Federation (EHF-SAS). Association of diet and headache. J Headache Pain. 2019;20:106.
• 13. Martin VT, Vij B. Diet and headache: Part 1. Headache. 2016;56:1543-52.
• 14. Martin VT, Vij B. Diet and headache: Part 2. Headache. 2016;56:1553-62.
• 15. Zaeem Z, Zhou L, Dilli E. Headaches: A review of the role of dietary factors. Curr Neurol Neurosci Rep. 2016;16:101.
• 16. Marcus DA, Scharff L, Turk D, Gourley LM. A double-blind provocative study of chocolate as a trigger of headache. Cephalalgia. 1997;17:855-62.
• 17. Wöber C, Brannath W, Schmidt K, Kapitan M, Rudel E, Wessely P, et al. Prospective analysis of factors related to migraine attacks: the PAMINA study. Cephalalgia. 2007;27:304-14.
• 18. Takeshima T, Ishizaki K, Fukuhara Y, Ijiri T, Kusumi M, Wakutani Y et al. Population-based door-to-door survey of migraine in Japan: The Daisen study. Headache. 2004;44:8-19.
• 19. Bánk J, Márton S. Hungarian migraine epidemiology. Headache. 2000;40:164-9.
• 20. Ulrich V, Russell MB, Jensen R, Olesen J. A comparison of tension-type headache in migraineurs and in non-migraineurs: a population-based study. Pain. 1996;67:501-6.
• 21. Russell MB, Rasmussen BK, Fenger K, Olesen J. Migraine without aura and migraine with aura are distinct clinical entities: a study of four hundred and eighty-four male and female migraineurs from the general population. Cephalalgia. 1996;16:239-45.
• 22. Yadav RK, Kalita J, Misra UK. A study of triggers of migraine in India. Pain Med. 2010;11:44-7.
• 23. Xie YJ, Lin M, Wong YT, Yan L, Zhang D, Gao Y. Migraine attacks and relevant trigger factors in undergraduate nursing students in Hong Kong: A Cross-Sectional Study. J Pain Res. 2022;15:701-13.
• 24. Milde-Busch A, Blaschek A, Borggräfe I, Heinen F, Straube A, von Kries R. Associations of diet and lifestyle with headache in high-school students: results from a cross-sectional study. Headache. 2010;50:1104-14.
• 25. Hagen K, Thoresen K, Stovner LJ, Zwart J-A. High dietary caffeine consumption is associated with a modest increase in headache prevalence: Results from the Head-HUNT Study. J Headache Pain. 2009;10:153-9.
• 26. Gazerani P. Migraine and Diet. Nutrients. 2020;12:1658