Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels

Necmettin Aktepe; Ayşe Baran; Cumali Keskin

doi:10.31015/2025.2.29

EN

Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels

Abstract

In recent years, interest in the eco-friendly manufacturing of metal nanoparticles from plant extracts has surged. Nonetheless, no research has examined the combined antibacterial and anticancer properties of SeNPs synthesized with Solanum tuberosum (S. tuberosum) extract. This study involved the synthesis of selenium nanoparticles (ST-SeNPs) utilizing phytochemicals with reducing and capturing properties derived from the aqueous extract of S. tuberosum shell through a green synthesis approach. To determine the unique characteristics of ST-SeNPs nanoparticles, a variety of techniques were used, including scanning electron microscopy (SEM), zeta potential analysis, transmission electron microscopy (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), UV-visible (UV-Vis) spectroscopy, and energy dispersive X-ray spectrometry (EDX). The optical characteristics of ST-SeNPs were validated using UV-Vis measurement, revealing the peak absorbance at 350 nm. FTIR examination verified the presence of functional groups on the surface of the produced ST-SeNPs nanoparticles. Upon examination of the SEM results, it was concluded that the synthesized SeNPs exhibited uniform distribution and possessed a round morphology. The anticancer efficacy of the produced nanoparticles on the A549 lung cancer cell line and OVCAR-3 ovarian cancer cell line after 24 and 48 hours of exposure was assessed using the MTT test. It was established that elevated concentration inhibited cell growth. The inhibitory efficacy of SeNPs against the proliferation of Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Candida albicans (C. albicans) was assessed using the disk diffusion agar technique. The evaluated SeNPs exhibited antibacterial efficacy against bacterial and yeast cells. The results indicate that ST-SeNPs produced via green synthesis can serve as anticancer and antibacterial agents.

Keywords

Solanum tuberosum peels, Selenium nanoparticle, Anticancer, Antimicrobial

Supporting Institution

Our study was supported by Mardin Artuklu University Scientific Research Projects Coordination, project number MAÜ.BAP.24.LEE.059.

Thanks

I would like to thank Mardin Artuklu University Scientific Research Projects Coordination for supporting our work and my co-author friends for their contributions.

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Details

Primary Language

English

Subjects

Agricultural Biotechnology Diagnostics

Journal Section

Research Article

Authors

Necmettin Aktepe ^*
0000-0003-2192-9049
Türkiye

Ayşe Baran
0000-0002-2317-0489
Türkiye

Cumali Keskin
0000-0003-3758-0654
Türkiye

Publication Date

June 26, 2025

Submission Date

April 18, 2025

Acceptance Date

June 5, 2025

Published in Issue

Year 2025 Volume: 9 Number: 2

DOI

https://doi.org/10.31015/2025.2.29

IZ

https://izlik.org/JA53JT29TR

APA

Aktepe, N., Baran, A., & Keskin, C. (2025). Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels. International Journal of Agriculture Environment and Food Sciences, 9(2), 559-569. https://doi.org/10.31015/2025.2.29

AMA

1.Aktepe N, Baran A, Keskin C. Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels. int. j. agric. environ. food sci. 2025;9(2):559-569. doi:10.31015/2025.2.29

Chicago

Aktepe, Necmettin, Ayşe Baran, and Cumali Keskin. 2025. “Cytotoxic and Antimicrobial Analysis of Biosynthesized Selenium Nanoparticles from Solanum Tuberosum Peels”. International Journal of Agriculture Environment and Food Sciences 9 (2): 559-69. https://doi.org/10.31015/2025.2.29.

EndNote

Aktepe N, Baran A, Keskin C (June 1, 2025) Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels. International Journal of Agriculture Environment and Food Sciences 9 2 559–569.

IEEE

[1]N. Aktepe, A. Baran, and C. Keskin, “Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels”, int. j. agric. environ. food sci., vol. 9, no. 2, pp. 559–569, June 2025, doi: 10.31015/2025.2.29.

ISNAD

Aktepe, Necmettin - Baran, Ayşe - Keskin, Cumali. “Cytotoxic and Antimicrobial Analysis of Biosynthesized Selenium Nanoparticles from Solanum Tuberosum Peels”. International Journal of Agriculture Environment and Food Sciences 9/2 (June 1, 2025): 559-569. https://doi.org/10.31015/2025.2.29.

JAMA

1.Aktepe N, Baran A, Keskin C. Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels. int. j. agric. environ. food sci. 2025;9:559–569.

MLA

Aktepe, Necmettin, et al. “Cytotoxic and Antimicrobial Analysis of Biosynthesized Selenium Nanoparticles from Solanum Tuberosum Peels”. International Journal of Agriculture Environment and Food Sciences, vol. 9, no. 2, June 2025, pp. 559-6, doi:10.31015/2025.2.29.

Vancouver

1.Necmettin Aktepe, Ayşe Baran, Cumali Keskin. Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels. int. j. agric. environ. food sci. 2025 Jun. 1;9(2):559-6. doi:10.31015/2025.2.29

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Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels

Abstract

Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels

Abstract

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Supporting Institution

Thanks

References

Details

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Subjects

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Authors

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Submission Date

Acceptance Date

Published in Issue

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