Acute toxicity of titanium dioxide nanoparticles on some serum parameters and enzyme activities of Cyprinus carpio

Yıl 2020, Cilt: 5 Sayı: 4, 704 - 710, 31.12.2020

Mustafa Tunçsoy , Servet Duran

https://doi.org/10.35229/jaes.818260

Cited By: 1

Öz

Titanium dioxide nanoparticles (TiO2 NPs) are widely used in industries for electronics, packaging, food, and cosmetics. Due to their extensive usage of these NPs pose a great threat to the aquatic environments. Effects of 25 and 50 mg/L waterborne TiO2 NPs on serum glucose, total protein and cholesterol levels and serum AST, ALT and ALP activities of C. carpio were determined after 24, 48 and 96 hours of exposure.
No mortality was observed during the experiments. Serum glucose level increased at 48 and 96 hours while serum total protein and cholesterol levels unchanged compared with control at the end of the 96 hours. There was also an increased in serum AST, ALT and ALP activities compared with control at 96 hours of exposure to TiO2 NPs.

Anahtar Kelimeler

Titanium dioxide, Nanoparticle, Serum parameters, C. carpio

Titanyum dioksit nanopartiküllerinin Cyprinus carpio’da bazı serum parametreleri ile serum enzim aktiviteleri üzerine akut toksisitesi

Öz

Titanyum dioksit nanopartikülleri (TiO2 NP) elektronik malzemeler, paketleme, yiyecek endüstrisi ve kozmetik ürünler başta olmak üzere yaygın kullanıma sahip nanopartiküllerdir. Bu yaygın kullanım sonucu doğaya daha yüksek düzeylerde salınmaları, özellikle su organizmaları için tehlike oluşturmaktadır. Bu araştırmada TiO2 NP’nin 25 ve 50 mg/L derişimlerinin 24, 48 ve 96 saatlik sürelerle etkisinde C. carpio’da serum glikoz, total protein ve kolesterol düzeyleri ile serum AST, ALT ve ALP enzim aktivitelerinin belirlenmesi amaçlanmıştır.
Belirlenen süre ve derişimlerde TiO2 NP etkisinde balıklarda mortalite gözlenmemiştir. TiO2 NP etkisinde serum glikoz düzeyi her iki derişimde de 48 ve 96 saatlik etki süresinde kontrole oranla önemli düzeyde artış gösterirken, serum total protein ve kolesterol düzeyinde tüm süre ve derişimlerde kontrole oranla herhangi bir değişiklik gözlenmemiştir. Serum AST, ALT ve ALP enzim aktivitesi ise her iki derişimde de 96 saatlik etki süresinde kontrole oranla önemli düzeyde artış göstermiştir.

Anahtar Kelimeler

Titanyum dioksit, Nanopartikül, Serum parametreleri, C. carpio

Kaynakça

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