Diagnostic Performance and Reproducibility of the Radiological Society of North America Expert Consensus Statement on COVID-19 Pneumonia

Öz

Aim: To investigate the interobserver and intraobserver agreement and performance of the Radiological Society of North America Expert agreement declaration in assessing chest computed tomography (CT) findings related to new COVID-19 pneumonia. Materials and Methods: In this retrospective study, conducted from March 15 to April 1, 2020, 113 patients with suspected COVID-19 infection were enrolled. All patients underwent investigation using real-time reverse transcription polymerase chain reaction (RT-PCR) and chest CT scans. Chest CT features were categorized by three radiologists following the North American Consensus Statement. Characteristic and indeterminate features were considered as Group A, while atypical and negative features were considered as Group B. The interobserver and intraobserver agreement of the imaging features were evaluated, along with the sensitivity and specificity of the consensus statement. Results: The study population comprised 113 consecutive patients. Out of the 113 patients, 61 tested positive for RT-PCR. Group A (categories 3 and 4) consisted of 89 patients, while Group B (categories 1 and 2) included 24 patients. The ICC score for intraobserver and interobserver agreement was 0.996 (95% CI) and 0.971 (95% CI), respectively. Using RT-PCR as a reference standard, the sensitivity, specificity, negative predictive value, and positive predictive value of CT findings (group A, B) for COVID-19 pneumonia were 82%, 25%, 56.1%, and 54.1%, respectively. Conclusion: The expert agreement declaration on reporting new COVID-19 pneumonia tomography findings is a well-designed, reliable, and reproducible standardized CT reporting language. It demonstrates excellent intra- and interobserver agreement.

Anahtar Kelimeler

• Coronavirus disease-2019
• Pneumonia
• Computed Tomography
• Real-Time Reverse Transcription Polymerase Chain Reaction

COVID-19 Pnömonisine İlişkin Kuzey Amerika Radyoloji Derneği Uzman Konsensusunun Tanısal Performansı

Öz

Amaç: COVID-19 pnömonisinde gözlenen toraks bilgisayarlı tomografi (BT) bulgularının değerlendirilmesinde Kuzey Amerika Radyoloji Derneği Uzman Anlaşması beyanının gözlemciler arası ve gözlemci içi uyumunu ve performansını araştırmayı amaçladık. Gereç ve Yöntemler: 15 Mart - 1 Nisan 2020 tarihleri arasında yürütülen bu retrospektif çalışmaya COVID-19 enfeksiyonu şüphesi olan 113 hasta dahil edildi. Tüm hastalara real time reverse transkriptaz polimeraz zincir reaksiyonu (RT-PCR) ve toraks BT incelemesi yapıldı. Toraks BT özellikleri Kuzey Amerika Uzlaşı Beyannamesine göre üç radyolog tarafından kategorize edildi. Karakteristik ve intermediate özellikler A grubu olarak kabul edildi. Atipik ve negatif özellikler B grubu olarak kabul edildi. Görüntüleme özelliklerinin gözlemciler arası ve gözlemci içi uyumu konsensüs ifadesinin duyarlılığı ve özgüllüğü ile birlikte değerlendirildi. Bulgular: Çalışma popülasyonu 113 ardışık hastadan oluşmaktadır. 113 hastanın 61’i RT-PCR pozitifti. Grup A (kategori 3+4) 89 hastadan ve grup B (kategori 1+2) 24 hastadan oluşuyordu. Gözlemci içi ve gözlemciler arası uyum için skoru sırasıyla 0.996 (%95 CI) ve 0.971 (%95 CI) idi. Referans standart olarak RT-PCR kullanıldığında, BT bulgularının (grup A, B) COVID-19 pnömonisi için duyarlılık, özgüllük, negatif ve pozitif prediktif değerleri sırasıyla %82, %25, %56.1 ve %54.1 idi. Sonuç: Yeni COVID-19 pnömonisi tomografi bulgularının raporlanmasına ilişkin uzman anlaşması beyanı, iyi tasarlanmış, güvenilir ve tekrarlanabilir standart raporlama dilidir ve gözlemciler arası ve gözlemci içi mükemmel bir uyum gösterir.

Anahtar Kelimeler

• Koronavirüs Hastalığı-2019
• Pnömoni
• Bilgisayarlı Tomografi
• Polimeraz Zincir Reaksiyonu

Kaynakça

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