Analysis of the Patients with Elevated Creatinine Kinase (CK) Level at Emergency Department

Öz

 

Objective: The aim of this study was to analyse the clinical conditions and the causes of the CK elevation of the patients with elevated CK level at emergency department.

Material and Method: This clinical study was conducted on a group of 118 patients admitted to emergency department with several clinical conditions and whose CK level is elevated, during six months between January and June. Claim of CK from patients was performed by the phsician who work at the Emergency Department and request of indication was not questioned. The age, gender, clinical conditions, history, drugs used and the exact diagnosis of the patients are gathered in a form previously prepared . Patients with high CK level was divided into 3 groups. Results were analysed stastistically.

Results: Kreatin Kinaz elevation was found on % 66,1 (n=78) male patients, % 33,9 (n=40) female patients respectively. CK levels were between 203 and 6274. Mean CK level was 812,17±975,45 and median CK level was 417. According to the clinical findings, we have found that ; with a rate of 29,7 % chest pain was most commonly seen. According to the diagnosis; acute coronary syndromes (ACS) ( 24,6 %) was most commonly seen, fallowed by infections (16,1 %) and drugs (13,6 %). Accordig to the drugs the most common drugs which caused CK elevation  was beta blokers, fallowed by statins and diuretics.

Conclusion: Among the patients who admitted to the Emergency Department, CK height is mostly seen at cardiovasculer system disorders, and dependent of this, the chest pain is most commonly seen complaint in patients with elevated CK levels.

Anahtar Kelimeler

• Emergency Department,Kreatinin Kinase,Rabdomyolysis.

Acil Serviste Kreatinin Kinaz (CK) Yüksekliği Saptanan Hastaların Analizi

Öz

Amaç: Acil Servise başvuran ve CK yüksekliği tespit edilen hastaların geliş şikâyetlerini ve CK yüksekliği yapan nedenleri tespit etmeyi amaçladık.

Materyal ve Metod: Bu klinik çalışma, Ocak ve Haziran ayları arasında altı ay boyunca çeşitli şikâyetlerle acil servisimize başvuran ve yapılan ilk rutin tetkikleri neticesinde CK yüksekliği saptanan 118 hasta ile yapıldı. Hastalardan CK tetkikinin istemi acil serviste çalışan doktorun isteği doğrultusunda gerçekleşti ve CK istem endikasyonu sorgulanmadı. CK değerleri yüksek olan 118 hastanın yaşı, cinsiyeti, şikâyeti, öz geçmişi, kullandığı ilaçları ve kesin tanılarını içeren bilgiler ayrı olarak hazırlanmış formda toplandı. CK yüksekliği saptanan hastalar 3 gruba ayrıldı. Elde edilen sonuçlar istatistiksel olarak değerlendirildi.

Bulgular: Hastaların % 66,1’i erkek, % 33,9’u kadındı. CK değerleri 203 ile 6274 arasında değişmekte olup ortalama CK değeri 812,17±975,45 olarak saptandı; medyan değeri ise 417 olarak bulundu. Olguların şikâyetleri incelendiğinde; %29,7 oran ile göğüs ağrısı ve göğüste sıkışma hissi en sık olarak tespit edildi. CK yüksekliği nedenlerine baktığımızda ilk sırada %24,6 ile AKS (Akut Koroner Sendromlar), sonrasında %16,1 ile enfeksiyon ve %13,6 ile ilaç kullanımı geldiği tespit edildi. Çalışmamızda CK yükselmesi yapan ilaçları incelediğimizde birinci sırada beta blokörlerin olduğu, bunu sırası ile statinler ve diüretiklerin izlediği tespit edildi.

Sonuç:  Acil Servise başvuran hastalar arasında serum CK yüksekliği en fazla kardiyovasküler sistem hastalıklarında görülmektedir. Buna bağlı olarak da CK yüksekliği olan hastalarda en sık şikâyet göğüs ağrısı olarak karşımıza çıkmaktadır.

Anahtar Kelimeler

• Acil Servis,Kreatinin Kinaz,Rabdomiyoliz.

Kaynakça

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