Klotho Protein and Type 2 Diabetes Mellitus

Eda Dokumacıoğlu; Hatice Iskender

doi:10.35206/jan.1087260

TR EN

Klotho Protein and Type 2 Diabetes Mellitus

Öz

Diabetes mellitus (DM) is considered an epidemic disease by many countries and shown as one of the leading causes of death in western societies. In the development of the disease, the underlying pathophysiological mechanisms are complex and multifactorial. The frequency of DM increases with age, and the severity of events such as oxidative stress and inflammation increases in patients diagnosed with DM. The Klotho (KL) protein, defined as a new anti-aging protein as a result of the studies on aging mechanisms and it has an important functions on glucose homeostasis and insulin secretion. In this review study, the relationship between KL protein and DM is explained by compiling the information in the articles published in PubMed indexed journals between 2002-2020. In conclusion, a decrease in KL levels plays a role in type 2 DM and the development of nephropathy and vascular diseases caused by type 2 DM.

Anahtar Kelimeler

oxidative stress, Type 2 Diabetes mellitus, Klotho, inflammation

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Derleme

Yazarlar

Eda Dokumacıoğlu ^*
0000-0002-2223-1331
Türkiye

Hatice Iskender
0000-0002-8063-4972
Türkiye

Yayımlanma Tarihi

31 Aralık 2022

Gönderilme Tarihi

13 Mart 2022

Kabul Tarihi

29 Aralık 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 5 Sayı: 2

DOI

https://doi.org/10.35206/jan.1087260

IZ

https://izlik.org/JA44XN42XX

APA

Dokumacıoğlu, E., & Iskender, H. (2022). Klotho Protein and Type 2 Diabetes Mellitus. Journal of Apitherapy and Nature, 5(2), 133-146. https://doi.org/10.35206/jan.1087260

AMA

1.Dokumacıoğlu E, Iskender H. Klotho Protein and Type 2 Diabetes Mellitus. Journal of Apitherapy and Nature. 2022;5(2):133-146. doi:10.35206/jan.1087260

Chicago

Dokumacıoğlu, Eda, ve Hatice Iskender. 2022. “Klotho Protein and Type 2 Diabetes Mellitus”. Journal of Apitherapy and Nature 5 (2): 133-46. https://doi.org/10.35206/jan.1087260.

EndNote

Dokumacıoğlu E, Iskender H (01 Aralık 2022) Klotho Protein and Type 2 Diabetes Mellitus. Journal of Apitherapy and Nature 5 2 133–146.

IEEE

[1]E. Dokumacıoğlu ve H. Iskender, “Klotho Protein and Type 2 Diabetes Mellitus”, Journal of Apitherapy and Nature, c. 5, sy 2, ss. 133–146, Ara. 2022, doi: 10.35206/jan.1087260.

ISNAD

Dokumacıoğlu, Eda - Iskender, Hatice. “Klotho Protein and Type 2 Diabetes Mellitus”. Journal of Apitherapy and Nature 5/2 (01 Aralık 2022): 133-146. https://doi.org/10.35206/jan.1087260.

JAMA

1.Dokumacıoğlu E, Iskender H. Klotho Protein and Type 2 Diabetes Mellitus. Journal of Apitherapy and Nature. 2022;5:133–146.

MLA

Dokumacıoğlu, Eda, ve Hatice Iskender. “Klotho Protein and Type 2 Diabetes Mellitus”. Journal of Apitherapy and Nature, c. 5, sy 2, Aralık 2022, ss. 133-46, doi:10.35206/jan.1087260.

Vancouver

1.Eda Dokumacıoğlu, Hatice Iskender. Klotho Protein and Type 2 Diabetes Mellitus. Journal of Apitherapy and Nature. 01 Aralık 2022;5(2):133-46. doi:10.35206/jan.1087260

e-ISSN: 2667-4734 Yayın Modeli: Sürekli Yayın Atıf Dizinleri: TR Dizin

Klotho Protein and Type 2 Diabetes Mellitus

Klotho Proteini ve Tip 2 Diabetes Mellitus

Öz

Anahtar Kelimeler

Klotho Protein and Type 2 Diabetes Mellitus

Öz

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Bölüm

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