Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat
Öz
This study investigated the effects of chestnut honey on growth and development. A total of 14 Wistar albino rats were divided into two groups: the Control group (C) and the Chestnut Honey group (CH). During the 23-day experimental period, weekly measurements of body length and weight were recorded, body mass index (BMI) was calculated, and growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels were assessed. At the end of the treatment, no statistically significant differences were observed between the Chestnut Honey and Control groups in terms of body weight and body length (p = 0.355, p = 0.772, p = 0.232). Furthermore, biochemically, IGF-1 levels did not differ significantly between groups (p = 0.919), whereas GH levels were significantly reduced in the chestnut honey group compared to the control group (p < 0.001). These results indicate that chestnut honey is a safe dietary component that does not induce weight gain or adversely affect IGF-1 metabolism.
Anahtar Kelimeler
chesnut honey, weight, height, BMI, Growth hormone, IGF-1
Destekleyen Kurum
Düzce University
Proje Numarası
2025.21.09.1614
Etik Beyan
This study was reviewed by the Düzce University Animal Experiments Local Ethics Committee and approved ethically by decision dated May 15, 2024, numbered 2024-05-02.
Teşekkür
This study was supported by Düzce University Scientific Research Projects (BAP) under project number 2025.21.09.1614.
Kaynakça
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