Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat

Zeynep Hızal; Tuğçe Çaprazlı; Eda Nur Gözderesi; Meral Kekeçoğlu

doi:10.35206/jan.1778899

EN TR

Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat

Öz

This study investigated the effects of chestnut honey on growth and development. A total of 14 Wistar albino rats were divided into two groups: the Control group (C) and the Chestnut Honey group (CH). During the 23-day experimental period, weekly measurements of body length and weight were recorded, body mass index (BMI) was calculated, and growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels were assessed. At the end of the treatment, no statistically significant differences were observed between the Chestnut Honey and Control groups in terms of body weight and body length (p = 0.355, p = 0.772, p = 0.232). Furthermore, biochemically, IGF-1 levels did not differ significantly between groups (p = 0.919), whereas GH levels were significantly reduced in the chestnut honey group compared to the control group (p < 0.001). These results indicate that chestnut honey is a safe dietary component that does not induce weight gain or adversely affect IGF-1 metabolism.

Anahtar Kelimeler

chesnut honey, weight, height, BMI, Growth hormone, IGF-1

Kestane Balının Sıçanlarda Büyüme Parametreleri ve Büyüme ile İlgili Hormonlar Üzerindeki Etkileri

Öz

Bu çalışmada, kestane balının büyüme ve gelişme üzerindeki etkilerini araştırıldı. Toplam 14 Wistar albino sıçan, Kontrol grubu (C) ve Kestane Balı grubu (CH) olmak üzere iki gruba ayrıldı. 23 günlük deney süresi boyunca, haftalık vücut uzunluğu ve vücut ağırlığı ölçümleri kaydedilmiş, vücut kitle indeksi (BMI) hesaplanmış ve büyüme hormonu (GH) ve insülin benzeri büyüme faktörü 1 (IGF-1) düzeyleri değerlendirilmiştir. Tedavinin sonunda, kestane balı grubu ile kontrol grubu arasında vücut ağırlığı ve vücut uzunluğu açısından istatistiksel olarak anlamlı bir fark gözlenmemiştir (p = 0,355, p = 0,772, p = 0,232). Ayrıca, biyokimyasal olarak, IGF-1 düzeyleri gruplar arasında önemli ölçüde farklılık göstermezken (p = 0,919), GH düzeyleri kontrol grubuna kıyasla kestane balı grubunda önemli ölçüde azalmıştır (p < 0,001). Bu sonuçlar, kestane balının kilo alımına neden olmayan ve IGF-1 metabolizmasını olumsuz etkilemeyen güvenli bir besin bileşeni olduğunu göstermektedir.

Anahtar Kelimeler

kestane balı, ağırlık, boy, BMI, büyüme hormonu, IGF-1

Destekleyen Kurum

Düzce Üniversitesi

Proje Numarası

2025.21.09.1614

Etik Beyan

Bu çalışma, Düzce Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu tarafından incelenmiş ve 15 Mayıs 2024 tarihli ve 2024-05-02 numaralı karar ile etik açıdan onaylanmıştır.

Teşekkür

Bu çalışma, Düzce Üniversitesi Bilimsel Araştırma Projeleri (BAP) tarafından 2025.21.09.1614 numaralı proje kapsamında desteklenmiştir.

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Gıda Mühendisliği

Bölüm

Araştırma Makalesi

Yazarlar

Zeynep Hızal
0009-0001-4419-181X
Türkiye

Tuğçe Çaprazlı
0000-0001-9109-0969
Türkiye

Eda Nur Gözderesi Bu kişi benim
0009-0003-5115-6638
Türkiye

Meral Kekeçoğlu ^*
0000-0002-2564-8343
Türkiye

Yayımlanma Tarihi

31 Aralık 2025

Gönderilme Tarihi

5 Eylül 2025

Kabul Tarihi

9 Ekim 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 8 Sayı: 2

DOI

https://doi.org/10.35206/jan.1778899

IZ

https://izlik.org/JA59RN97FD

APA

Hızal, Z., Çaprazlı, T., Gözderesi, E. N., & Kekeçoğlu, M. (2025). Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat. Journal of Apitherapy and Nature, 8(2), 253-267. https://doi.org/10.35206/jan.1778899

AMA

1.Hızal Z, Çaprazlı T, Gözderesi EN, Kekeçoğlu M. Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat. Journal of Apitherapy and Nature. 2025;8(2):253-267. doi:10.35206/jan.1778899

Chicago

Hızal, Zeynep, Tuğçe Çaprazlı, Eda Nur Gözderesi, ve Meral Kekeçoğlu. 2025. “Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat”. Journal of Apitherapy and Nature 8 (2): 253-67. https://doi.org/10.35206/jan.1778899.

EndNote

Hızal Z, Çaprazlı T, Gözderesi EN, Kekeçoğlu M (01 Aralık 2025) Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat. Journal of Apitherapy and Nature 8 2 253–267.

IEEE

[1]Z. Hızal, T. Çaprazlı, E. N. Gözderesi, ve M. Kekeçoğlu, “Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat”, Journal of Apitherapy and Nature, c. 8, sy 2, ss. 253–267, Ara. 2025, doi: 10.35206/jan.1778899.

ISNAD

Hızal, Zeynep - Çaprazlı, Tuğçe - Gözderesi, Eda Nur - Kekeçoğlu, Meral. “Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat”. Journal of Apitherapy and Nature 8/2 (01 Aralık 2025): 253-267. https://doi.org/10.35206/jan.1778899.

JAMA

1.Hızal Z, Çaprazlı T, Gözderesi EN, Kekeçoğlu M. Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat. Journal of Apitherapy and Nature. 2025;8:253–267.

MLA

Hızal, Zeynep, vd. “Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat”. Journal of Apitherapy and Nature, c. 8, sy 2, Aralık 2025, ss. 253-67, doi:10.35206/jan.1778899.

Vancouver

1.Zeynep Hızal, Tuğçe Çaprazlı, Eda Nur Gözderesi, Meral Kekeçoğlu. Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat. Journal of Apitherapy and Nature. 01 Aralık 2025;8(2):253-67. doi:10.35206/jan.1778899

e-ISSN: 2667-4734 Yayın Modeli: Sürekli Yayın Atıf Dizinleri: TR Dizin

Effects of Chestnut Honey on Growth Parameters and Growth-Related Hormones in Rat

Öz

Anahtar Kelimeler

Kestane Balının Sıçanlarda Büyüme Parametreleri ve Büyüme ile İlgili Hormonlar Üzerindeki Etkileri

Öz

Anahtar Kelimeler

Destekleyen Kurum

Proje Numarası

Etik Beyan

Teşekkür

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster