The Use of Egg Yolk Antibodies for Food Protection and Immunity

Yıl 2020, Cilt: 3 Sayı: 1, 65 - 74, 30.06.2020

Aamir Iqbal , Syed Rizwan Ali Shah İbrahim Sadi Çetingül , Eyüp Eren Gültepe , Abdul Qudoos İsmail Bayram

Öz

The chicken immune system has been studied for many years and these studies have contributed substantially to our understanding of the fundamental concepts of immunology and the development of different immunoglobulin classes. It is thus surprising that only a small fraction of the antibodies presently used in laboratories are of avian origin. Laying hen produces more yolk antibodies than a rabbit can produce during the same time period, and the animal care costs are lower for the chicken compared to the rabbit. Chicken antibodies offer many advantages to the traditional mammalian antibodies when used for the detection of mammalian antigen. Chicken antibodies can also be used to avoid interference in immunological assays caused by the human complement system, rheumatoid factors, human anti-mouse IgG antibodies or human and bacterial Fc-receptors.

Anahtar Kelimeler

Immune system, antibodies, yolk antibodies, mammalian antigen

Kaynakça

• 1. Araújo, A. S., Lobato, Z. I. P., Chávez-Olórtegui, C., & Velarde, D. T. (2010). Brazilian IgY-Bothrops antivenom: Studies on the development of a process in chicken egg yolk. Toxicon. https://doi.org/10.1016/j.toxicon.2009.11.004
• 2. Boudaoud, A., & Mamache, B. (2012). Use of egg yolk antibodies to predict optimal age of vaccination against Infectious Bursal Disease (IBD) in broilers. International Journal of Poultry Science. https://doi.org/10.3923/ijps.2012.138.142
• 3. C., V., M., B., P., C., L., S., F., F., & V., P. (2011). Egg yolk IgY: Protection against rotavirus induced diarrhea and modulatory effect on the systemic and mucosal antibody responses in newborn calves. Veterinary Immunology and Immunopathology.
• 4. Chase, C. C. L., Hurley, D. J., & Reber, A. J. (2008). Neonatal Immune Development in the Calf and Its Impact on Vaccine Response. Veterinary Clinics of North America - Food Animal Practice. https://doi.org/10.1016/j.cvfa.2007.11.001
• 5. Cser, L., Gladkih, I. A., Hädge, D., & Ambrosius, H. (1982). X-ray small-angle scattering study of general structure of chicken immunoglobulin Y. Immunology Letters. https://doi.org/10.1016/0165-2478(82)90071-2
• 6. Dávalos-Pantoja, L., Ortega-Vinuesa, J. L., Bastos-González, D., & Hidalgo-Álvarez, R. (2000). A comparative study between the adsorption of IgY and IgG on latex particles. Journal of Biomaterials Science, Polymer Edition. https://doi.org/10.1163/156856200743931
• 7. Dias da Silva, W., & Tambourgi, D. V. (2010). IgY: A promising antibody for use in immunodiagnostic and in immunotherapy. Veterinary Immunology and Immunopathology. https://doi.org/10.1016/j.vetimm.2009.12.011
• 8. Duffy, D., Rouilly, V., Libri, V., Hasan, M., Beitz, B., David, M., … Albert, M. L. (2014). Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli. Immunity. https://doi.org/10.1016/j.immuni.2014.03.002
• 9. Ehsani, A., Naghibi, S. S., Aminzare, M., Keykhosravi, K., & Hashemi, M. (2019). Extraction of specific egg yolk antibodies and application in chitosan coating: effect on microbial and sensory properties of rainbow trout fillet during chilled storage. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.9442
• 10. Fink, A. L., Williams, K. L., Harris, E., Alvine, T. D., Henderson, T., Schiltz, J., … Bradley, D. S. (2017). Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement. PLoS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0005721
• 11. Grando, T. H., Baldissera, M. D., de Sá, M. F., do Carmo, G. M., Porto, B. C. Z., Aguirre, G. S. V., … Monteiro, S. G. (2017). Avian antibodies (IgY) against Trypanosoma cruzi: Purification and characterization studies. Journal of Immunological Methods. https://doi.org/10.1016/j.jim.2017.07.002
• 12. Greunke, K., Braren, I., Alpers, I., Blank, S., Sodenkamp, J., Bredehorst, R., & Spillner, E. (2008). Recombinant IgY for improvement of immunoglobulin-based analytical applications. Clinical Biochemistry. https://doi.org/10.1016/j.clinbiochem.2008.07.004
• 13. Grosso, M. C., Bellingeri, R. V., Motta, C. E., Alustiza, F. E., Picco, N. Y., & Vivas, A. B. (2015). Immunohistochemical distribution of early pregnancy factor in ovary, oviduct and placenta of pregnant gilts. Biotechnic and Histochemistry. https://doi.org/10.3109/10520295.2014.931599
• 14. Hodek, P., & Stiborova, M. (2003). Chicken antibodies-superior alternative for conventional immunoglobulins. PROCEEDINGS-INDIAN NATIONAL SCIENCE ACADEMY PART B.
• 15. Hou, Y. Y., Zhen, Y. H., Wang, D., Zhu, J., Sun, D. X., Liu, X. T., … Shu, X. H. (2014). Protective effect of an egg yolk-derived immunoglobulin (IgY) against Prevotella intermedia-mediated gingivitis. Journal of Applied Microbiology. https://doi.org/10.1111/jam.12419
• 16. Hu, B., Yang, X., Guo, E., Zhou, P., Xu, D., Qi, Z., & Deng, L. (2019). The preparation and antibacterial effect of egg yolk immunoglobulin (IgY) against the outer membrane proteins of Vibrio parahaemolyticus. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.9470
• 17. Kaur, B. P., & Secord, E. (2019). Innate Immunity. Pediatric Clinics of North America. https://doi.org/10.1016/j.pcl.2019.06.011
• 18. Kim, H. S., Lee, B., Han, S. Y., & Jung, Y. T. (2017). Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8. Acta Virologica. https://doi.org/10.4149/av_2017_02_03
• 19. Klemperer, F. (1893). Ueber natürliche Immunität und ihre Verwerthung für die Immunisirungstherapie. Archiv Für Experimentelle Pathologie Und Pharmakologie. https://doi.org/10.1007/BF01832882
• 20. Kovacs-Nolan, J., & Mine, Y. (2012). Egg Yolk Antibodies for Passive Immunity. Annual Review of Food Science and Technology. https://doi.org/10.1146/annurev-food-022811-101137
• 21. Lee, J., Babiuk, L. A., Harland, R., Gibbons, E., Elazhary, Y., & Yoo, D. (1995). Immunological response to recombinant VP8* subunit protein of bovine rotavirus in pregnant cattle. Journal of General Virology. https://doi.org/10.1099/0022-1317-76-10-2477
• 22. Ma, Y., Galluzzi, L., Zitvogel, L., & Kroemer, G. (2013). Autophagy and cellular immune responses. Immunity. https://doi.org/10.1016/j.immuni.2013.07.017
• 23. Malik, M. W., Ayub, N., & Qureshi, I. Z. (2006). Passive immunization using purified IgYs against infectious bursal disease of chickens in Pakistan. Journal of Veterinary Science. https://doi.org/10.4142/jvs.2006.7.1.43
• 24. Mitsuyama, M. (2008). Adaptive immunity. In Handbook of Listeria Monocytogenes. https://doi.org/10.1201/9781420051414.ch14
• 25. Müller, S., Schubert, A., Zajac, J., Dyck, T., & Oelkrug, C. (2015). IgY antibodies in human nutrition for disease prevention. Nutrition Journal. https://doi.org/10.1186/s12937-015-0067-3
• 26. Nimmerjahn, F., & Ravetch, J. V. (2007). Fc-Receptors as Regulators of Immunity. Advances in Immunology. https://doi.org/10.1016/S0065-2776(07)96005-8
• 27. Ozeki, M., tsuda, K., Hatta, H., & Hashimoto, K. (1992). Molecular Stability of Chicken and Rabbit Immunoglobulin G. Bioscience, Biotechnology, and Biochemistry. https://doi.org/10.1271/bbb.56.270
• 28. Pauly, D., Dorner, M., Zhang, X., Hlinak, A., Dorner, B., & Schade, R. (2009). Monitoring of laying capacity, immunoglobulin Y concentration, and antibody titer development in chickens immunized with ricin and botulinum toxins over a two-year period. Poultry Science. https://doi.org/10.3382/ps.2008-00323
• 29. Pauly, Diana, Chacana, P. A., Calzado, E. G., Brembs, B., & Schade, R. (2011). IgY Technology: Extraction of Chicken Antibodies from Egg Yolk by Polyethylene Glycol (PEG) Precipitation. Journal of Visualized Experiments. https://doi.org/10.3791/3084
• 30. Pradhan, S., Kumar, S., Singh, D., Sood, R. C., & Sehgal, R. (2007). Development of passive haemagglutination (PHA) and haemagglutination inhibition (HAI) technique for potency estimation of Cobra Antisnake Venom Serum (ASVS). Biologicals. https://doi.org/10.1016/j.biologicals.2006.08.001
• 31. Revathy, J., Karthika, S., Sentila, R., & Michael, A. (2014). In vitro evaluation of the efficacy of chicken egg yolk antibodies (IgY) generated against Propionibacterium acnes. International Journal of Cosmetic Science. https://doi.org/10.1111/ics.12097
• 32. Riera Romo, M., Pérez-Martínez, D., & Castillo Ferrer, C. (2016). Innate immunity in vertebrates: An overview. Immunology. https://doi.org/10.1111/imm.12597
• 33. Rose, M. E., Orlans, E., & Buttress, N. (1974). Immunoglobulin classes in the hen’s egg: Their segregation in yolk and white. European Journal of Immunology. https://doi.org/10.1002/eji.1830040715
• 34. Rudolf, J., Führer, M., Galler, B., Ansari, P., Hasenhindl, C., & Baumgartner, S. (2009). Differences in usability of rabbit IgG and chicken IgY after clean-up and impact on gold labelling properties. Journal of Immunological Methods. https://doi.org/10.1016/j.jim.2009.08.006
• 35. Schade, R., & Hlinak, A. (1996). Egg Yolk Antibodies, State of the Art and Future Prospects. ALTEX.
• 36. Schade, R., Staak, C., Hendriksen, C., Erhard, M., Hugl, H., Koch, G., … Straughan, D. (1996). The production of avian (egg yolk) antibodies: IgY. The report and recommendations of ECVAM workshop 21. In ATLA Alternatives to Laboratory Animals.
• 37. Sharma, G. K., Mahajan, S., Matura, R., Biswal, J. K., Ranjan, R., Subramaniam, S., … Pattnaik, B. (2017). Herd Immunity Against Foot-and-Mouth Disease Under Different Vaccination Practices in India. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.12478
• 38. Singh, N., Baby, D., Rajguru, J., Patil, P., Thakkannavar, S., & Pujari, V. (2019). Inflammation and cancer. Annals of African Medicine. https://doi.org/10.4103/aam.aam_56_18
• 39. Sun, S., Mo, W., Ji, Y., & Liu, S. (2001). Preparation and mass spectrometric study of egg yolk antibody (Igy) against rabies virus. Rapid Communications in Mass Spectrometry. https://doi.org/10.1002/rcm.271
• 40. Thu, H. M., Myat, T. W., Win, M. M., Thant, K. Z., Rahman, S., Umeda, K., … Choi, H. J. (2017). Chicken egg yolk antibodies (IgY) for prophylaxis and treatment of rotavirus diarrhea in human and animal neonates: A concise review. Korean Journal for Food Science of Animal Resources. https://doi.org/10.5851/kosfa.2017.37.1.1
• 41. Tini, M., Jewell, U. R., Camenisch, G., Chilov, D., & Gassmann, M. (2002). Generation and application of chicken egg-yolk antibodies. In Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology. https://doi.org/10.1016/S1095-6433(01)00508-6
• 42. Vega, C. G., & Parreño, V. (2014). Passive immunity strategies to control rotavirus diarrhea in neonatal calves. In Rotavirus Infections: Epidemiology, Clinical Characteristics and Treatment Options.
• 43. Ward, E. S. (2004). Acquiring maternal immunoglobulin: Different receptors, similar functions. Immunity. https://doi.org/10.1016/S1074-7613(04)00117-7
• 44. Wei, L. J., Alkarkhi, A. F. M., & Huda, N. (2019). Physicochemical properties of egg yolk powder from eggs of different types of bird. International Journal on Advanced Science, Engineering and Information Technology. https://doi.org/10.18517/ijaseit.9.1.3046
• 45. William, R., & Burch, R. (1959). The Principles of Humane Experimental Technique by W.M.S. Russell and R.L. Burch.
• 46. Xu, F. X., Xu, Y. P., Jin, L. J., Liu, H., Wang, L. H., You, J. S., … Li, X. Y. (2012). Effectiveness of egg yolk immunoglobulin (IgY) against periodontal disease-causing Fusobacterium nucleatum. Journal of Applied Microbiology. https://doi.org/10.1111/j.1365-2672.2012.05396.x
• 47. Xu, Y., Lin, H., Sui, J., & Cao, L. (2012). Effects of specific egg yolk antibody (IgY) on the quality and shelf life of refrigerated Paralichthys olivaceus. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.4693
• 48. Yoo, D., Lee, J., Harland, R., Gibbons, E., Elazhary, Y., & Babiuk, L. A. (1997). Maternal immunization of pregnant cattle with recombinant VP8* protein of bovine rotavirus elicits neutralizing antibodies to multiple serotypes: Colostral neutralizing antibody by rotavirus VP8*. Advances in Experimental Medicine and Biology. https://doi.org/10.1007/978-1-4899-1828-4_63