Mean trombosit volume in patients with retinopathy of prematurity

Abstract

Objective: We aimed to evaluate the mean platelet volume (MPV) in patients with retinopathy of prematurity (ROP) with respect to development of type 1 ROP Methods: The medical records of the premature infants were evaluated. Babies with a birth weight under 1500 g and a gestational age under 32 weeks were enrolled to the study. Birth weight, gestational age, onset and grade of retinopathy, presence of plus disease were analyzed. At the time of type 1 ROP diagnosis, blood samples were obtained. In the patients without type 1 ROP the blood samples were also obtained at similar gestational age. Hemoglobin, hematocrit, platelet count, and MPV results were recorded. Results: Sixty-three infants were studied. 22 of them had type 1 ROP and 41 had not developed type 1 ROP. The mean gestational age and the mean birth weight between groups were not statistically significant. The mean MPV values in patients with type 1 ROP and without type 1 ROP was 9,1±2,0 fL and 9,4±1,8 fL, respectively (p=0.61). Conclusion: The results demonstrated that MPV values were not associated with severity of ROP in our study population. J Clin Exp Invest 2014; 5 (2): 443-446

Keywords

• Retinopathy of prematurity, mean trombosit volume, type 1 ROP

Mean trombosit volume in patients with retinopathy of prematurity

Öz

Amaç: Bu çalışmada prematüre retinopatisi (PR) olan hastalarda tip 1 PR gelişen ve gelişmeyen hastaların ortalama trombosit hacmi (OTH) karşılaştırılmıştır. Yöntemler: Çalışma prematüre yeni doğanların hastane kayıtları incelenerek yapılmıştır. 1500 gr ağırlık altında ve doğum haftası 32 haftadan küçük olan bebekler bu çalışmaya dahil edilmiştir. Doğum ağırlıkları, doğum haftası, retinopatinin evresi, artı hastalık varlığı araştırılmıştır. Tip 1 PR tanısı koyulduğu zaman hastalardan kan alınmıştır. Tip 1 PR tanısı almayan hastalardan da benzer gestasyonel yaşlarda kan alınmıştır. Tam kan sayımında; hemoglobin, hematokrit, trombosit sayısı ve OTH değerleri kaydedilmiştir. Bulgular: Altmış üç PR\'li hasta bu çalışmaya dahil edildi. Bu hastaların 22 tanesinde tip 1 PR saptanırken, 41 tanesinde saptanmadı. Ortalama doğum haftası ve doğum ağırlığı gruplar arasında istatistiksel farklılık saptanmadı. Ortalama OTH tip 1 PR gelişen olgularda 9,1±2,0 fL iken tip 1 PR gelişmeyen olgularda 9,4±1,8 fL idi (p=0,61) Sonuçlar: Çalışmamızda OTH değerleri tip 1 PR gelişen ve gelişmeyen PR\'li hastalarda farklı saptanmamıştır.

Anahtar Kelimeler

• Prematüre retinopatisi, ortalama trombosit hacmi, tip 1 PR

Kaynakça

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