Impact of Maternal Obesity on Early Neonatal Outcomes
Öz
Objective: To evaluate the impact of maternal obesity on maternal, perinatal, and early neonatal outcomes.
Methods: This retrospective cohort was conducted in a tertiary care university hospital between 2017 and 2021 in Istanbul. Women with a first-trimester body mass index (BMI) of >30.0 kg/m² were included in the maternal obesity group, and their maternal, perinatal clinical characteristics, and neonatal outcomes at the early postnatal period were compared with the age- and neonatal sex-matched non-obese control group (BMI <30.0 kg/m²).
Results: The study included 1252 mother–infant dyads, with 626 infants in each group. In terms of pregnancy complications, maternal obesity was significantly associated with higher rates of both pregestational and gestational hypertension and diabetes mellitus (all p<0.001), and increased cesarean delivery rates (p<0.001). Infants born to obese mothers had significantly higher birth weight and higher rates of being large for gestational age (LGA) (p<0.001). These infants also demonstrated higher neonatal intensive care unit admission rates (p<0.001) compared with infants born to non-obese mothers. Early neonatal metabolic complications, including early formula supplementation (p<0.001), hypoglycemia (p = 0.02), and hypernatremia (p = 0.005), were significantly more frequent in the maternal obesity group.
Conclusions: Maternal obesity is associated with adverse maternal, perinatal, and early neonatal outcomes, including delivery mode, postnatal neonatal metabolic adaptation, and early feeding difficulties. Early identification of high-risk pregnancies, individualized antenatal care, and structured postnatal feeding support may help reduce preventable maternal and neonatal complications.
Anahtar Kelimeler
Kaynakça
- 1. World Health Organization. Fact sheet on overweight and obesity [Internet]. Geneva: World Health Organization; 2025. [updated 2025 Dec]. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
- 2. Vats H, Saxena R, Sachdeva MP, Walia GK, Gupta V. Impact of maternal pre-pregnancy body mass index on maternal, fetal and neonatal adverse outcomes in the worldwide populations: A systematic review and meta-analysis. Obes Res Clin Pract. 2021 Nov-Dec;15(6):536-545. doi: 10.1016/j.orcp.2021.10.005. Epub 2021 Nov 12. PMID: 34782256.
- 3. Catalano PM, Shankar K. Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child. BMJ. 2017 Feb 8;356:j1. doi: 10.1136/bmj.j1. PMID: 28179267; PMCID: PMC6888512.
- 4. Mustafa HJ, Seif K, Javinani A, Aghajani F, Orlinsky R, Alvarez MV, et al. Gestational weight gain below instead of within the guidelines per class of maternal obesity: a systematic review and meta-analysis of obstetrical and neonatal outcomes. Am J Obstet Gynecol MFM. 2022 Sep;4(5):100682. doi: 10.1016/j.ajogmf.2022.100682. Epub 2022 Jun 18. PMID: 35728780.
- 5. Iwama N, Yokoyama M, Yamashita H, Miyakoshi K, Yasuhi I, Kawasaki M, et al.; DREAMBee Study Gestational Diabetes Mellitus Group. Impact of maternal overweight/obesity and high fasting plasma glucose on adverse perinatal outcomes in early gestational diabetes mellitus. J Diabetes Investig. 2025 Apr;16(4):744-754. doi: 10.1111/jdi.14411. Epub 2025 Jan 24. PMID: 39856811; PMCID: PMC11970313.
- 6. Blomberg M. Maternal obesity, mode of delivery, and neonatal outcome. Obstet Gynecol. 2013 Jul;122(1):50-55. doi: 10.1097/AOG.0b013e318295657f. PMID: 23743457.
- 7. Ruager-Martin R, Hyde MJ, Modi N. Maternal obesity and infant outcomes. Early Hum Dev. 2010 Nov;86(11):715-22. doi: 10.1016/j.earlhumdev.2010.08.007. Epub 2010 Sep 16. PMID: 20846795.
- 8. Meghelli L, Vambergue A, Drumez E, Deruelle P. Complications of pregnancy in morbidly obese patients: what is the impact of gestational diabetes mellitus? J Gynecol Obstet Hum Reprod. 2020; 49(1):101628. doi:10.1016/j.jogoh.2019.101628
Ayrıntılar
Birincil Dil
İngilizce
Konular
Yenidoğan
Bölüm
Araştırma Makalesi
Yazarlar
Meltem Bor
*
0000-0002-4171-2149
Türkiye
Elif Kirit
Bu kişi benim
0000-0003-2658-4115
Türkiye
Beril Yaşa
0000-0001-7871-3121
Türkiye
Leyla Bilgin
Bu kişi benim
0000-0003-4035-1713
Türkiye
Zeynep İnce
0000-0002-7304-099X
Türkiye
Asuman Çoban
0000-0001-6573-242X
Türkiye
Yayımlanma Tarihi
15 Haziran 2026
Gönderilme Tarihi
11 Ocak 2026
Kabul Tarihi
23 Mart 2026
Yayımlandığı Sayı
Yıl 2026 Cilt: 26 Sayı: 1