Sık Hastalanan Çocuğa Yaklaşım
Yıl 2018,
, 47 - 51, 01.07.2018
Murat Sütçü
Manolya Kara
Ayper Somer
Öz
Aile hekimleri ve pediyatristler sık hastalanma yakınması ile başvuran çocuklarla sık olarak karşı karşıya kalmak- tadırlar. Başka bir açıdan bakmak gerekirse aileler altta yatan ciddi hastalıklar hakkında endişe duymaktadırlar. Bu çocukların yaklaşık yarısı tamamıyla sağlıklı iken, 1/3’ü atopiktir. Primer immün yetmezliğin çocukluk çağı ana bulgusu yineleyen infeksiyonlardır. Hekimlerin ana görevi hızlı tanı ve tedavisi gereken primer immün yet- mezlikli çocukları sağlıklı ve atopik çocuklardan ayır- maktır
Kaynakça
- Stiehm ER. Approach to the child with recurrent infec- tions. www.uptodate.com. last updated: Dec 07, 2015.
- Akhater SA. Approach to the child with recurrent infections. J Family Community Med. 2009;16:77-82.
- Primary İmmünodeficiency Association. Publications: 10 warning signs of a primary immünodeficiency. www.pia.org.uk/publications/10_signs_of_pia/10_ signs_01.htm. Accessed March 14, 2011.
- Subbarayan A, Colarusso G, Hughes SM, et al. Clinical features that identify children with primary immunede- ficiency diseases. Pediatrics 2011;127:810-6.
- https://doi.org/10.1542/peds.2010-3680
- Environmental tobacco smoke: a hazard to children. American Academy of Pediatrics Committee on Environmental Health. Pediatrics 1997;99:639-46.
- https://doi.org/10.1542/peds.99.4.639
- Daly KA, Hoffman HJ, Kvaerner KJ, et al. Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media. Int J Pediatr Otorhinolaryngol. 2010;74:231-40.
- https://doi.org/10.1016/j.ijporl.2009.09.006
- James KM, Peebles RS Jr, Hartert TV. Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility? J Allergy Clin Immunol. 2012;130:343-51.
- https://doi.org/10.1016/j.jaci.2012.05.056
- MacGinnitie A, Aloi F, Mishra S. Clinical characteris- tics of pediatric patients evaluated for primary immu- nodeficiency. 2011;22:671-5. Allergy Immunol.
- https://doi.org/10.1111/j.1399-3038.2011.01167.x
- Skoda-Smith S, Barrett DJ. When earaches and sore throats become more than a pain in the neck. Contemp Pediatr. 2000;17:156-66.
- Bonilla FA, Khan DA, Ballas ZK, et al. Practice para- meter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol. 2015;136: 1186-205.
- https://doi.org/10.1016/j.jaci.2015.04.049
- Tosi FM. Normal and impaired immunologic responses to infection. In Feigin RD, Cherry JD, Demmler GJ, Kaplan SL, eds. Textbook of Pediatric Infectious Diseases, 7th Edition, Philadelphia, Saunders. 2014: 55-106.
- Tiller TL Jr, Liddle KJ. Immunodeficiency problems in children. JSC Med Assoc. 2000;96:225-8.
- Cantoni N, Recher M. Primary and secondary immuno- deficiencies. Ther Umsch. 2014;71:31-43.
- https://doi.org/10.1024/0040-5930/a000479
- Ellison RT, Kohler PF, Curd JG, Judson FN, Reller LB. Prevalence of congenital or acquired complement defi- ciency in patients with sporadic meningococcal disea- se. N Engl J Med. 1983;308:913-6.
- https://doi.org/10.1056/NEJM198304213081601
- Buckley RH. The multiple causes of human SCID. J Clin Invest. 2004;114:1409-11.
- https://doi.org/10.1172/JCI200423571
Approach to the Child with Recurrent Infections
Yıl 2018,
, 47 - 51, 01.07.2018
Murat Sütçü
Manolya Kara
Ayper Somer
Öz
Family practitioners and pediatricians often come across with children who are presented with the recurrent compla- ints of becoming sick. Although families worry about the underlying serious disorders, aproximately half of these children are completely healthy where as one third of them are atopic. Recurrent infections are the main features of the childhood presentation of primary immunodeficiency dise- ases. The primary duty of the physicians is to differentiate the children requiring prompt diagnosis and treatment from those healthy and the atopic ones
Kaynakça
- Stiehm ER. Approach to the child with recurrent infec- tions. www.uptodate.com. last updated: Dec 07, 2015.
- Akhater SA. Approach to the child with recurrent infections. J Family Community Med. 2009;16:77-82.
- Primary İmmünodeficiency Association. Publications: 10 warning signs of a primary immünodeficiency. www.pia.org.uk/publications/10_signs_of_pia/10_ signs_01.htm. Accessed March 14, 2011.
- Subbarayan A, Colarusso G, Hughes SM, et al. Clinical features that identify children with primary immunede- ficiency diseases. Pediatrics 2011;127:810-6.
- https://doi.org/10.1542/peds.2010-3680
- Environmental tobacco smoke: a hazard to children. American Academy of Pediatrics Committee on Environmental Health. Pediatrics 1997;99:639-46.
- https://doi.org/10.1542/peds.99.4.639
- Daly KA, Hoffman HJ, Kvaerner KJ, et al. Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media. Int J Pediatr Otorhinolaryngol. 2010;74:231-40.
- https://doi.org/10.1016/j.ijporl.2009.09.006
- James KM, Peebles RS Jr, Hartert TV. Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility? J Allergy Clin Immunol. 2012;130:343-51.
- https://doi.org/10.1016/j.jaci.2012.05.056
- MacGinnitie A, Aloi F, Mishra S. Clinical characteris- tics of pediatric patients evaluated for primary immu- nodeficiency. 2011;22:671-5. Allergy Immunol.
- https://doi.org/10.1111/j.1399-3038.2011.01167.x
- Skoda-Smith S, Barrett DJ. When earaches and sore throats become more than a pain in the neck. Contemp Pediatr. 2000;17:156-66.
- Bonilla FA, Khan DA, Ballas ZK, et al. Practice para- meter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol. 2015;136: 1186-205.
- https://doi.org/10.1016/j.jaci.2015.04.049
- Tosi FM. Normal and impaired immunologic responses to infection. In Feigin RD, Cherry JD, Demmler GJ, Kaplan SL, eds. Textbook of Pediatric Infectious Diseases, 7th Edition, Philadelphia, Saunders. 2014: 55-106.
- Tiller TL Jr, Liddle KJ. Immunodeficiency problems in children. JSC Med Assoc. 2000;96:225-8.
- Cantoni N, Recher M. Primary and secondary immuno- deficiencies. Ther Umsch. 2014;71:31-43.
- https://doi.org/10.1024/0040-5930/a000479
- Ellison RT, Kohler PF, Curd JG, Judson FN, Reller LB. Prevalence of congenital or acquired complement defi- ciency in patients with sporadic meningococcal disea- se. N Engl J Med. 1983;308:913-6.
- https://doi.org/10.1056/NEJM198304213081601
- Buckley RH. The multiple causes of human SCID. J Clin Invest. 2004;114:1409-11.
- https://doi.org/10.1172/JCI200423571