Çocukluk Çağında Nötropeniye Yaklaşım
Yıl 2012,
, 53 - 59, 01.04.2012
Ömer Devecioğlu
Sevinç Gümüş
Öz
Nötropeni, çocukluk çağlarında çok önemli hematolojik sorunlardan biridir. Konjenital ve edinsel nedenlerle mey- dana gelebilir. Nötrofil sayısının çok düştüğü durumlarda
Kaynakça
- 1. Fioredda F, Calvillo M, Bonanomi S, et al. Congenital and acquired neutropenia consensus on diagnosis from the Neutropenia Commitee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica). Pediatr Blood Cancer 2011;57(1):10-7. http://dx.doi.org/10.1002/pbc.23108 PMid:21448998
- 2. Bonilla MA. Disorders of white blood cells. In Manual of Pediatric Hematology and Oncology, Lanzkowsky ed, 5th edition, Amsterdam, Elsevier, 2011, pp:272-320.
- 3. Dale DC, Person RE, Bolyard AA, et al. Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 2000;96:2317-22. PMid:11001877
- 4. Donadieu J, Fenneteau O, Beaupain B, et al. Congenital neutropenia: diagnosis, molecular bases and patient management. Orphanet J Rare Dis 2011;6:26 Review. PMid:21595885 PMCid:3127744
- 5. Dinauer MC and Newburger PE. Quantitative granulocyte and mononuclear phagocyte disorders. In Nathan and Oski’s Hematology of Infancy and Chilhood, Orkin SH, Nathan DG, Ginsburg D, Look AT, Fisher DE, Lux SE eds, 7th edition, Philadelphia, Saunders Elsevier, 2009, pp:1137-52.
- 6. Boxer LA and Newburger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer 2007;49:609-14. http://dx.doi.org/10.1002/pbc.21282 PMid:17584878
- 7. Berliner N, Horwitz M, Loughran TP. Congenital and acquired neutropenia. Hematoogy Am Soc Educ Program 2004. pp:63-79. PMid:15561677
- 8. Vandenberghe P, Beel C. Severe congenital neutropenia,a genetically heterogeneous disease group with an increased risk of AML/MDS. Pediatr Rep 2011;3(Suppl 2):e9. PMid:22053285 PMCid:3206537 http://dx.doi.org/10.4081/pr.2011.s2.e9
- 9. Kostmann R. Infantile genetic agranulocytosis; agranulocytosis infantilis hereditaria. Acta Paediatr Suppl 1956;45:1-78. PMid:13326376
- 10. Ward AC, van Aesch YM, Gits J, et al. Novel point mutation in the extracellular domain of the granulocyte colonystimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. J Exp Med 1999;190:497-507. PMid:10449521 PMCid:2195597 http://dx.doi.org/10.1084/jem.190.4.497
- 11. Freeman MH, Bonilla, Frier C, et al. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy. Blood 2000; 96:429-36. PMid:10887102 http://dx.doi.org/10.1186/1750-1172-6-26
- 12. Menasche G, Ho CH, Sanal O, et al. Griscelli syndrome restricted to hypopigmentation results a melanophillin defect (GS3) or a MYO5A F-exon deletion. J Clin Invest 2003;112 (3):450-6. PMid:12897212 PMCid:166299
- 13. Bohn G, Allroth A, Brandes G, et al. A novel human primary immonodeficiencıency syndrome caused by deficiency of the endosomal adaptor protein. Nature Medicine 2007;13:1:39- 45. PMid:17195838 http://dx.doi.org/10.1038/nm1528
- 14. Bux J, Behrens G, Jaeger G,Welte K. Diagnosis and clinical course of autoimmune neutropenia in infancy: analysis of 240 cases. Blood 1998;91(1):181-6. PMid:9414283
- 15. Newburger PE, Boxer LA. Leukopenia. In Nelson Textbook of Pediatrics, Kliegman RM, Stanton BF, St.Geme III JW, Schor NF, Behrman RE eds, 19th edition, Philadelphia, Elsevier Saunders, 2009, pp:746-52.
Approach to Childhood Neutropenia
Yıl 2012,
, 53 - 59, 01.04.2012
Ömer Devecioğlu
Sevinç Gümüş
Öz
Neutropenia is one of the most serious hematological prob- lems in childhood. Neutropenia, either acquired or conge- nital, is a decrease in neutrophil count
Kaynakça
- 1. Fioredda F, Calvillo M, Bonanomi S, et al. Congenital and acquired neutropenia consensus on diagnosis from the Neutropenia Commitee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica). Pediatr Blood Cancer 2011;57(1):10-7. http://dx.doi.org/10.1002/pbc.23108 PMid:21448998
- 2. Bonilla MA. Disorders of white blood cells. In Manual of Pediatric Hematology and Oncology, Lanzkowsky ed, 5th edition, Amsterdam, Elsevier, 2011, pp:272-320.
- 3. Dale DC, Person RE, Bolyard AA, et al. Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 2000;96:2317-22. PMid:11001877
- 4. Donadieu J, Fenneteau O, Beaupain B, et al. Congenital neutropenia: diagnosis, molecular bases and patient management. Orphanet J Rare Dis 2011;6:26 Review. PMid:21595885 PMCid:3127744
- 5. Dinauer MC and Newburger PE. Quantitative granulocyte and mononuclear phagocyte disorders. In Nathan and Oski’s Hematology of Infancy and Chilhood, Orkin SH, Nathan DG, Ginsburg D, Look AT, Fisher DE, Lux SE eds, 7th edition, Philadelphia, Saunders Elsevier, 2009, pp:1137-52.
- 6. Boxer LA and Newburger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer 2007;49:609-14. http://dx.doi.org/10.1002/pbc.21282 PMid:17584878
- 7. Berliner N, Horwitz M, Loughran TP. Congenital and acquired neutropenia. Hematoogy Am Soc Educ Program 2004. pp:63-79. PMid:15561677
- 8. Vandenberghe P, Beel C. Severe congenital neutropenia,a genetically heterogeneous disease group with an increased risk of AML/MDS. Pediatr Rep 2011;3(Suppl 2):e9. PMid:22053285 PMCid:3206537 http://dx.doi.org/10.4081/pr.2011.s2.e9
- 9. Kostmann R. Infantile genetic agranulocytosis; agranulocytosis infantilis hereditaria. Acta Paediatr Suppl 1956;45:1-78. PMid:13326376
- 10. Ward AC, van Aesch YM, Gits J, et al. Novel point mutation in the extracellular domain of the granulocyte colonystimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. J Exp Med 1999;190:497-507. PMid:10449521 PMCid:2195597 http://dx.doi.org/10.1084/jem.190.4.497
- 11. Freeman MH, Bonilla, Frier C, et al. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy. Blood 2000; 96:429-36. PMid:10887102 http://dx.doi.org/10.1186/1750-1172-6-26
- 12. Menasche G, Ho CH, Sanal O, et al. Griscelli syndrome restricted to hypopigmentation results a melanophillin defect (GS3) or a MYO5A F-exon deletion. J Clin Invest 2003;112 (3):450-6. PMid:12897212 PMCid:166299
- 13. Bohn G, Allroth A, Brandes G, et al. A novel human primary immonodeficiencıency syndrome caused by deficiency of the endosomal adaptor protein. Nature Medicine 2007;13:1:39- 45. PMid:17195838 http://dx.doi.org/10.1038/nm1528
- 14. Bux J, Behrens G, Jaeger G,Welte K. Diagnosis and clinical course of autoimmune neutropenia in infancy: analysis of 240 cases. Blood 1998;91(1):181-6. PMid:9414283
- 15. Newburger PE, Boxer LA. Leukopenia. In Nelson Textbook of Pediatrics, Kliegman RM, Stanton BF, St.Geme III JW, Schor NF, Behrman RE eds, 19th edition, Philadelphia, Elsevier Saunders, 2009, pp:746-52.