Neonatal Boğmaca: Vaka Sunumu

Öz

Boğmaca, Bordetella pertussis’in neden olduğu, solunum yollarının aşı ile önlenebilir oldukça bulaşıcı bir infeksiyon hastalığıdır. Her yaş grubunda görülmekle birlikte aşı programı tamamlanmamıştır ve özellikle 6 ayın altındaki bebekler ve küçük çocuklarda ağır seyredip hastaneye yatış ve mortaliteye neden olabilmektedir. Boğmaca riskini azaltmak için, ergen ve erişkinleri dolayısıyla bebekleri boğmacadan korumak için, okul öncesi çocuklar ve ergenlere pekiştirme dozlarının uygulanması ve ulusal aşı takvimimize pekiştirme boğmaca aşı dozlarının eklenmesi düşünülmelidir. Bu makalede boğmaca tanısı alan bir yenidoğanın güncel literatürle birlikte sunulması hedeflenmiştir.

Anahtar Kelimeler

• Boğmaca,bordetella pertussis,yenidoğan

Neonatal Pertussis: A Case Report

Öz

Pertussis is a highly contagious respiratory system infection of Bordetella pertussis which can be prevented with an immunization protocol. Although it can be seen in all age groups, the disease pursues a more severe course resulting in hospital stay and mortality in infants under 6 months and small children who have not completed their vaccination program. In order to reduce the risk of pertussis in adolescents and adults and therefore in infants , booster vaccinations should be administered to pre-school children and adolescents and also inclusion of boosters in the nationwide inoculation program should be considered. This article aims to present the case of a newborn diagnosed with pertussis in the light of the latest literature.

Anahtar Kelimeler

• Pertussis,bordetella pertussis,newborn

Kaynakça

1. Halasa NB, O’Shea A, Shi JR, LaFleur BJ, Edwards KM. Poor immune responses to a birth dose of diphteria, tetanus, and acellular pertussis vaccine, J Pediatr 2008;153:327-32. http://dx.doi.org/10.1016/j.jpeds.2008.03.011
2. Greenberg D, Bamberger E, Ben-Shimol S, Gershtein R, Golan D, Srugo I. Pertussis is underdiagnosed in infants hospitalized with lower respiratory tract infection in the pedi- atric intensive care unit, Med Sci Monit 2007;13:475-80.
3. Wood N, Quinn HE, McIntyre P, Eliot E. Pertussis in infants: preventing deaths and hospitalisations in the very young, Paedtr Child Health 2008;44:161-5. http://dx.doi.org/10.1111/j.1440-1754.2008.01292.x PMid:18377367
4. Deaths from pertussis are inderestimated in England, Arch Dis Child 2002;86:336-8. http://dx.doi.org/10.1136/adc.86.5.336 PMid:11970924 PMCid:1751114 aşı dozları gerekli mi?, Çocuk Enf Derg 2009;3:14-8. es, In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Disease; New York: Churchill Livingstone 2003:880-8.
5. Duration of immunity against pertussis after natural infection or vaccination, Pediatr Infect Dis 2005;24:58-61. http://dx.doi.org/10.1097/01.inf.0000160914.59160.41 PMid:15876927 humoral and cell-mediated immunity after acellular pertussis vaccination compares favorably with whole-cell vaccines 6 years after booster vaccination in the second year of life, Vaccine 2007;25:1390-7. http://dx.doi.org/10.1016/j.vaccine.2006.10.048 PMid:17134795
6. Pertussis of adults and infants, Lancet Infect Dis 2002;2:744- http://dx.doi.org/10.1016/S1473-3099(02)00452-8
7. KM, Baker CJ. Prevelance of pertussis antibodies in mater- nal delivery, cord and infant serum, J Infect Dis 2004;190:335- http://dx.doi.org/10.1086/421033 PMid:15216470 Opn Infect Dis 2001;14:329-35. PMid:11964852
8. MA. Recent findings on pertussis epidemiology in Turkey, Eur J Clin Infect Dis 2008;27:335-41. http://dx.doi.org/10.1007/s10096-007-0442-x PMid:6756909

9. Armangil D, Tekinalp G, Yurdakök M, Yalçın E. Maternal pertussis is hazardous for a newborn: a case report, Turk J Ped ;52:202-6. with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants, J Pediatr 2008;152:655-0. http://dx.doi.org/10.1016/j.jpeds.2007.09.034 PMid:18410769
10. Potential strategies to reduce the burden of pertussis, Pediatr Infect Dis J 2005;24:69-74. http://dx.doi.org/10.1097/01.inf.0000160917.29723.03 PMid:15876930
11. Duration of immunity against pertussis after natural infection or vaccination, Pediatr Infect Dis J 2005;24:858-61. http://dx.doi.org/10.1097/01.inf.0000160914.59160.41 PMid:15876927 sis, Pediatr Infect Dis 2005;24:10-8. http://dx.doi.org/10.1097/01.inf.0000160708.43944.99 PMid:15876918 of a five component acellular pertussis vaccine combined with diphteria and tetanus toxoids and inactivated poliovirus vacci- ne is safe and immunogenic in adolescents and adults. Pediatr Infect Dis J 2000;19:276-3. http://dx.doi.org/10.1097/00006454-200004000-00003
12. Aksakal F, Coplu N, Ceyhan M, Sonmez C, Ozkan S, Esen B, Ilhan M, Aygun R. High incidence of pertussis among schoolchildren with prolonged cough in Turkey, Tohoku J Exp Med 2007;211:353-8. http://dx.doi.org/10.1620/tjem.211.353 PMid:17409675 tussis in children with prolonged cough, Scand J Infect Dis ;40:314-9. http://dx.doi.org/10.1080/00365540701689659 PMid:17934983