Öz
Milroy hastalığı; lenfatik damarların konjenital gelişimsel anomalisine bağlı olarak ortaya çıkan ve her iki ayak sır- tından başlayıp alt ekstremiteye doğru ilerleyen ödem ile karakterizedir. Yedi aylık kız hasta doğumundan itibaren her iki ayak ve bacak bölgesinde şişlik yakınması ile poli- kliniğimize getirildi. Fizik muayenesinde her iki ayak sırtı ve bacaklarda gode bırakan ödem mevcuttu. Alt ekstremite lenfosintigrafisinde enjeksiyon bölgesi proksimalinde len- fatik klerens izlenmeyen vakaya Milroy hastalığı tanısı konuldu. Doğumda alt ekstremitelerde ödemi olan vakalar- da ayırıcı tanıda Milroy hastalığının düşünülmesi gerektiği vurgulandı
Anahtar Kelimeler
Primer lenfödem lenfosintigrafi ekstremitede ödem Milroy hastalığı
Kaynakça
- Mehta SD, Robinson RJ, Bern SA. Pedal manifestations of Milroy’s disease. J Am Pediatr Med Assoc 1996; 86:400-2
- Camitta BM. The lymphatic system. In: Behrman RE, Klieg- man RM, Jenson HB, eds. Nelson Textbook of Pediatrics, 17th ed. Philadelphia: WB Saunders 2004; 1677-8. lymphedema. J Vasc Surg 1986; 3:181-4. diagnosis of Milroy’s primary congenital lymphedema. Prenat Diagn 2002; 22:823-6.
- Irrthum A, Karkkainen MJ, Devriendt K, Alitalo K, Vikkula M. Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Am J Hum Genet 2000; 67:295-301.
- Noninvasive evaluation of the lymphatic system with lymphos- cintigraphy: a prospective, semiquantitative analysis in 386 extremities. J Vasc Surg 1993; 18:773-82.
- Diameters of lymphatic capillaries in patients with different forms of primary lymphedema. Lymphology 1990; 23:140-4.
Öz
Milroy disease is characterized by edema that starts from the dorsum of foot and progresses to lower extremities due to a congenital anomaly of lenfatic vessels. A 7-month-old girl was brought to our outpatient clinic with complaints of bilateral swelling of the legs and feet. At physical examina- tion edema was present on the dorsum of feet and legs. In lymphoscintigraphy lymphatic clearance was not detected in the proximal injection region and the case was diagno- sed as Milroy disease. Milroy disease should be thought in the differential diagnosis of cases with edema in the lower extremities at birth
Anahtar Kelimeler
Premier lymphedema lymphoscintigraphy edema in extremity Milroy disease
Kaynakça
- Mehta SD, Robinson RJ, Bern SA. Pedal manifestations of Milroy’s disease. J Am Pediatr Med Assoc 1996; 86:400-2
- Camitta BM. The lymphatic system. In: Behrman RE, Klieg- man RM, Jenson HB, eds. Nelson Textbook of Pediatrics, 17th ed. Philadelphia: WB Saunders 2004; 1677-8. lymphedema. J Vasc Surg 1986; 3:181-4. diagnosis of Milroy’s primary congenital lymphedema. Prenat Diagn 2002; 22:823-6.
- Irrthum A, Karkkainen MJ, Devriendt K, Alitalo K, Vikkula M. Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Am J Hum Genet 2000; 67:295-301.
- Noninvasive evaluation of the lymphatic system with lymphos- cintigraphy: a prospective, semiquantitative analysis in 386 extremities. J Vasc Surg 1993; 18:773-82.
- Diameters of lymphatic capillaries in patients with different forms of primary lymphedema. Lymphology 1990; 23:140-4.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Yazarlar | |
| Yayımlanma Tarihi | 1 Temmuz 2008 |
| Yayımlandığı Sayı | Yıl 2008 Cilt: 8 Sayı: 3 |