BibTex RIS Kaynak Göster

Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu

Yıl 2018, Cilt: 18 Sayı: 2, 93 - 96, 01.07.2018

Sevliya Öcal Demir Gürkan Atay Özge Kangallı Manolya Kara Özge Kaba Emel Çakar Mehmet Akif Durmuş Selda Hançerli Törün Gülden Gökçay Nezahat Gürler Ayper Somer

https://doi.org/10.5222/j.child.2018.58224

Öz

Linezolid ve vankomisin çok ilaca dirençli Gram pozitif bak- terilerin neden olduğu infeksiyonların tedavisinde günümüz- de başarıyla kullanılmaktadır. Etki spektrumlarının benzerli- ği nedeniyle klasik olarak birlikte kullanılmazlar. Bu maka- lede, ventilatör ilişkili pnömoni ve kateter ilişkili kan akımı infeksiyonu nedeniyle; vankomisin ve linezolid tedavilerinin beraber kullanıldığı ve tedaviye olumlu yanıt alınan bir has- tayı sunduk. Edindiğimiz tecrübe, linezolid tedavisi almakta olan hastada dirençli Gram pozitif bakteriler ile bakteriosta- tik tedavi verilemeyecek kadar ciddi yeni bir infeksiyon geliştiğinde, linezolid ve vankomisin tedavilerini beraber kullanabileceğimiz kanısı oluşturdu

Anahtar Kelimeler

Linezolid vankomisin pnömoni

Kaynakça

  • Donowitz GR, Cox HL. Linezolid and other oxazolidi- nones. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Dougllas, and Bennett’s Principles and Practice of Infectious Diseases, 7th ed. Philadelphia: Churchill Livingstone Elsevier, 2010: 471-4.
  • https://doi.org/10.1016/B978-0-443-06839-3.00033-3
  • Jacqueline C, Caillon J, Le Mabecque V, Miegeville AF, Donnio PY, Bugnon D, et al. In vitro activity of linezolid alone and in combination with gentamicin, vancomycin or rifampicin against methicillin-resistant Staphylococcus aureus by time-killcurve methods. J Antimicrob Chemother. 2003 Apr; 51:857-64.
  • https://doi.org/10.1093/jac/dkg160
  • Georges H, Leroy O, Alfandari S, Guery B, Roussel- Delvallez M, Dhennain C, et al. Pulmonary disposition of vancomycin in critically ill patients. Eur J Clin Microbiol Infect Dis. 1997;16:385-8.
  • https://doi.org/10.1007/BF01726369
  • Lamer C, de Beco V, Soler P, Calvat S, Fagon JY, Dombret MC, et al. Analysis of vancomycin entry into pulmonary lining fluid by bronkoalveolar lavage in critically ill patients. Antimicrob Agents Chemother 1993;37:281-6.
  • https://doi.org/10.1128/AAC.37.2.281
  • Kohno S, Yamaguchi K, Aikawa N, Sumiyama Y, Odagiri S, Aoki N, et al. Linezolid versus vancomycin for treatment of infections caused by meticillin- resis- tant Staphylococcus aures in Japan. J Antimicrob Chemother 2007;60:1361-9.
  • https://doi.org/10.1093/jac/dkm369
  • Wunderik RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A, et al. Linezolid in methicilin- resistant Staphylococcus aureus nosocomial pneumo- nia: a randomized, controlled study. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012;54:621-9.
  • https://doi.org/10.1093/cid/cir895
  • Reveles KR, Mortensen EM, Attridge RT, Frei CR. Comparative-effectiveness of vancomycin and linezo- lid as part of guideline-recommended empiric therapy for healthcare-associated pneumonia. BMC Res Notes. 2015;8:450.
  • https://doi.org/10.1186/s13104-015-1396-1
  • Takada H, Hifumi T, Nishimoto N, Kanemura T,Okada I, Kiriu N, et al. Linezolid versus vancomycin for noso- comial pneumonia due to methicillin-resistant Staphylococcus aueus in the elderly: A retrospective cohort analysis: Effectiveness of linezolid in the elderly. Am J Emerg Med. 2017;35:245-8.
  • https://doi.org/10.1016/j.ajem.2016.10.058
  • Ribes S, Pachon-Ibanez ME, Dominquez MA, Fernandez R, Tubau F, Ariza J, et al. In vitro and in vivo activities of linezolid alone and combined with vancomycin and imipenem against Staphylococcus aureus with reduced susceptibility to glycopeptides. Eur J Clin Microbiol Infect Dis 2010;29:1361-7.
  • https://doi.org/10.1007/s10096-010-1007-y
  • Davis JS, Van Hal S,Tong SY. Combination antibiotic treatment of serious methicillin-resistantStaphylococcus aureus infections. Semin Respir Crit Care Med. 2015;36:3-16.
  • https://doi.org/10.1055/s-0034-1396906

Vancomycin and Linezolid Combination for the Treatment of Resistant Gram-Positive Infection: Case Report

Yıl 2018, Cilt: 18 Sayı: 2, 93 - 96, 01.07.2018

Sevliya Öcal Demir Gürkan Atay Özge Kangallı Manolya Kara Özge Kaba Emel Çakar Mehmet Akif Durmuş Selda Hançerli Törün Gülden Gökçay Nezahat Gürler Ayper Somer

https://doi.org/10.5222/j.child.2018.58224

Öz

Linezolid and vancomycin have been used successfully in the treatment of infections caused by multidrug resistant gram-positive bacteria. Due to the similarity of the anti- bacterial spectrum, they are not classically used in combi- nation. Herein we present a patient who was successfully treated for catheter-related bloodstream infection and ventilator-associated pneumonia with linezolid and van- comycin combination. Our experience was that; linezolid and vancomycin combination can be used when either patient has a resistant Gram-positive bacterial infection or has a new onset severe infection that can not be treated with bacteriostatic agents

Anahtar Kelimeler

Linezolid vancomycin pneumonia

Kaynakça

  • Donowitz GR, Cox HL. Linezolid and other oxazolidi- nones. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Dougllas, and Bennett’s Principles and Practice of Infectious Diseases, 7th ed. Philadelphia: Churchill Livingstone Elsevier, 2010: 471-4.
  • https://doi.org/10.1016/B978-0-443-06839-3.00033-3
  • Jacqueline C, Caillon J, Le Mabecque V, Miegeville AF, Donnio PY, Bugnon D, et al. In vitro activity of linezolid alone and in combination with gentamicin, vancomycin or rifampicin against methicillin-resistant Staphylococcus aureus by time-killcurve methods. J Antimicrob Chemother. 2003 Apr; 51:857-64.
  • https://doi.org/10.1093/jac/dkg160
  • Georges H, Leroy O, Alfandari S, Guery B, Roussel- Delvallez M, Dhennain C, et al. Pulmonary disposition of vancomycin in critically ill patients. Eur J Clin Microbiol Infect Dis. 1997;16:385-8.
  • https://doi.org/10.1007/BF01726369
  • Lamer C, de Beco V, Soler P, Calvat S, Fagon JY, Dombret MC, et al. Analysis of vancomycin entry into pulmonary lining fluid by bronkoalveolar lavage in critically ill patients. Antimicrob Agents Chemother 1993;37:281-6.
  • https://doi.org/10.1128/AAC.37.2.281
  • Kohno S, Yamaguchi K, Aikawa N, Sumiyama Y, Odagiri S, Aoki N, et al. Linezolid versus vancomycin for treatment of infections caused by meticillin- resis- tant Staphylococcus aures in Japan. J Antimicrob Chemother 2007;60:1361-9.
  • https://doi.org/10.1093/jac/dkm369
  • Wunderik RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A, et al. Linezolid in methicilin- resistant Staphylococcus aureus nosocomial pneumo- nia: a randomized, controlled study. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012;54:621-9.
  • https://doi.org/10.1093/cid/cir895
  • Reveles KR, Mortensen EM, Attridge RT, Frei CR. Comparative-effectiveness of vancomycin and linezo- lid as part of guideline-recommended empiric therapy for healthcare-associated pneumonia. BMC Res Notes. 2015;8:450.
  • https://doi.org/10.1186/s13104-015-1396-1
  • Takada H, Hifumi T, Nishimoto N, Kanemura T,Okada I, Kiriu N, et al. Linezolid versus vancomycin for noso- comial pneumonia due to methicillin-resistant Staphylococcus aueus in the elderly: A retrospective cohort analysis: Effectiveness of linezolid in the elderly. Am J Emerg Med. 2017;35:245-8.
  • https://doi.org/10.1016/j.ajem.2016.10.058
  • Ribes S, Pachon-Ibanez ME, Dominquez MA, Fernandez R, Tubau F, Ariza J, et al. In vitro and in vivo activities of linezolid alone and combined with vancomycin and imipenem against Staphylococcus aureus with reduced susceptibility to glycopeptides. Eur J Clin Microbiol Infect Dis 2010;29:1361-7.
  • https://doi.org/10.1007/s10096-010-1007-y
  • Davis JS, Van Hal S,Tong SY. Combination antibiotic treatment of serious methicillin-resistantStaphylococcus aureus infections. Semin Respir Crit Care Med. 2015;36:3-16.
  • https://doi.org/10.1055/s-0034-1396906
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makaleleri
Yazarlar

Sevliya Öcal Demir Bu kişi benim

Gürkan Atay Bu kişi benim

Özge Kangallı Bu kişi benim

Manolya Kara Bu kişi benim

Özge Kaba Bu kişi benim

Emel Çakar Bu kişi benim

Mehmet Akif Durmuş Bu kişi benim

Selda Hançerli Törün Bu kişi benim

Gülden Gökçay Bu kişi benim

Nezahat Gürler Bu kişi benim

Ayper Somer Bu kişi benim

Yayımlanma Tarihi 1 Temmuz 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 18 Sayı: 2

Kaynak Göster

APA Öcal Demir, S., Atay, G., Kangallı, Ö., Kara, M., vd. (2018). Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu. Çocuk Dergisi, 18(2), 93-96. https://doi.org/10.5222/j.child.2018.58224
AMA Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş MA, Hançerli Törün S, Gökçay G, Gürler N, Somer A. Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu. Çocuk Dergisi. Temmuz 2018;18(2):93-96. doi:10.5222/j.child.2018.58224
Chicago Öcal Demir, Sevliya, Gürkan Atay, Özge Kangallı, Manolya Kara, Özge Kaba, Emel Çakar, Mehmet Akif Durmuş, Selda Hançerli Törün, Gülden Gökçay, Nezahat Gürler, ve Ayper Somer. “Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin Ve Linezolid Kombinasyonu: Vaka Sunumu”. Çocuk Dergisi 18, sy. 2 (Temmuz 2018): 93-96. https://doi.org/10.5222/j.child.2018.58224.
EndNote Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş MA, Hançerli Törün S, Gökçay G, Gürler N, Somer A (01 Temmuz 2018) Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu. Çocuk Dergisi 18 2 93–96.
IEEE S. Öcal Demir, “Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu”, Çocuk Dergisi, c. 18, sy. 2, ss. 93–96, 2018, doi: 10.5222/j.child.2018.58224.
ISNAD Öcal Demir, Sevliya vd. “Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin Ve Linezolid Kombinasyonu: Vaka Sunumu”. Çocuk Dergisi 18/2 (Temmuz 2018), 93-96. https://doi.org/10.5222/j.child.2018.58224.
JAMA Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş MA, Hançerli Törün S, Gökçay G, Gürler N, Somer A. Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu. Çocuk Dergisi. 2018;18:93–96.
MLA Öcal Demir, Sevliya vd. “Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin Ve Linezolid Kombinasyonu: Vaka Sunumu”. Çocuk Dergisi, c. 18, sy. 2, 2018, ss. 93-96, doi:10.5222/j.child.2018.58224.
Vancouver Öcal Demir S, Atay G, Kangallı Ö, Kara M, Kaba Ö, Çakar E, Durmuş MA, Hançerli Törün S, Gökçay G, Gürler N, Somer A. Dirençli Gram Pozitif İnfeksiyon Tedavisinde Vankomisin ve Linezolid Kombinasyonu: Vaka Sunumu. Çocuk Dergisi. 2018;18(2):93-6.