BibTex RIS Kaynak Göster

Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu

Yıl 2013, Cilt: 13 Sayı: 2, 73 - 76, 01.04.2013
https://doi.org/10.5222/j.child.2013.073

Öz

Henoch-Schönlein purpurası HSP ile ilişkili gastrointes- tinal sistem bulguları karın ağrısından obstrüksiyona dek değişebilmektedir. Tedavide oral ya da intravenöz steroid kullanılabilmekte, yanıt alınamadığında puls metilpredni- zolon PMP , intravenöz immunglobulin ya da plazmaferez gibi tedavi seçeneklerine geçilebilmektedir. Altı yaşında erkek vaka bilateral alt ekstremitelerde palpabl purpura, bileklerde artrit, lomber ve frontal bölgelerde ağrılı yumu- şak doku ödemleri, skrotal ekimotik görünüm bulguları ile HSP tanısı aldı. İzleminde şiddetli karın ağrısı ve kanlı dışkılama yakınmaları gelişti. İki mg/kg dozunda başlanan steroid tedavisine yanıt alınamayarak PMP tedavisine geçildi. Tedavinin ilk dozunda epididimit gelişen ve üçüncü dozunda halen kanlı dışkılama izlenen vakada üçüncü doz- dan sonra yakınmalerde gerileme saptandı

Kaynakça

  • Szer IS. Henoch-Schönlein purpura. Curr Opin Rheumatol ;6:25-31. http://dx.doi.org/10.1097/00002281-199401000-00005 PMid:8031676
  • Southwood TR. Incidence of Henoch-Schönlein purpura, Kawasaki disease, and rare vasculitides in children of diffe- rent ethnic origins. Lancet 2002;360:1197-202. http://dx.doi.org/10.1016/S0140-6736(02)11279-7
  • JC, et al. EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis ;65:936-41. http://dx.doi.org/10.1136/ard.2005.046300 PMid:16322081 PMCid:PMC1798210
  • Acute scrotum in Henoch-Schönlein purpura: fact or fiction? Turk J Pediatr 2012;54:194-7. PMid:22734311
  • Cassidy JT, Petty RE, Laxer RM, Lindsley CB, eds. Textbook of Pediatric Rheumatology. 5th ed. Philadelphia: WB Saunders; 2005:496-507. http://dx.doi.org/10.1016/B978-1-4160-0246-8.50029-2
  • Zhang Y, Huang X. Gastrointestinal involvement in Henoch- Schönlein purpura. Scand J Gastroenterol 2008;43:1038-43. http://dx.doi.org/10.1080/00365520802101861 PMid:18609159 et al. Gastrointestinal involvement in Henoch-Schönlein syndrome: CT findings. Am J Roentgenol 1997;168:965-8. http://dx.doi.org/10.2214/ajr.168.4.9124151 PMid:9124151
  • Paradis J. Perforation of large and small bowel in Henoch- Schonlein purpura. Int J Dermatol 1997;36:361-3. http://dx.doi.org/10.1111/j.1365-4362.1997.tb03098.x PMid:9199985
  • Heuschkel RB, Murch SH. Massive gastrointestinal hae- morrhage in isolated intestinal Henoch-Schonlein purpura with response to intravenous immunoglobulin infusion. Eur J Pediatr 2007;166:915-9. http://dx.doi.org/10.1007/s00431-006-0337-3 PMid:17120033
  • Warris A, Draaisma JM. Refractory severe intestinal vascu- litis due to Henoch-Schönlein purpura: successful treatment with plasmapheresis. Acta Paediatr 2006;95:622-3. http://dx.doi.org/10.1080/08035250500509180 PMid:16825146 treatment of gastrointestinal involvement in Henoch-Schönlein purpura with plasmapheresis. Pediatr Nephrol 2008;23:2103. http://dx.doi.org/10.1007/s00467-008-0886-y PMid:18546025
  • Schoenlein purpura: pathophysiologic mechanisms, the diag- nostic value of factor XIII, and therapeutic options. Eur J Pediatr 2007;166:1199-200. http://dx.doi.org/10.1007/s00431-007-0415-1 PMid:17333275 ment of mesenteric vasculitis caused by Henoch-Schönlein purpura with methylprednisolone pulse therapy. Clin Rheumatol 2003;22:140-2. http://dx.doi.org/10.1007/s10067-002-0676-z PMid:12740680

Severe Gastrointestinal Involvement in HenochSchoenlein Purpura: Case Report

Yıl 2013, Cilt: 13 Sayı: 2, 73 - 76, 01.04.2013
https://doi.org/10.5222/j.child.2013.073

Öz

Henoch-Schönlein purpura HSP associated gastrointesti- nal symptoms vary from abdominal pain to obstruction. Oral/intravenous steroid is the treatment of choice. In case of failure, pulse methylprednisolone PMP , intravenous immunoglobulin, plasmapheresis may be needed. A six- year-old boy was diagnosed with HSP owing to palpable purpura, arthritis, painful soft tissue edema in lumbar and frontal areas, ecchymosis in scrotum. During the follow-up, he had severe abdominal pain and bloody stool, which did not respond to steroid therapy 2 mg/kg . PMP was institu- ted. Epididymitis developed after the first dose. and he had bloody stool while receiving the third dose, but remission in complaints was observed thereafter

Kaynakça

  • Szer IS. Henoch-Schönlein purpura. Curr Opin Rheumatol ;6:25-31. http://dx.doi.org/10.1097/00002281-199401000-00005 PMid:8031676
  • Southwood TR. Incidence of Henoch-Schönlein purpura, Kawasaki disease, and rare vasculitides in children of diffe- rent ethnic origins. Lancet 2002;360:1197-202. http://dx.doi.org/10.1016/S0140-6736(02)11279-7
  • JC, et al. EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis ;65:936-41. http://dx.doi.org/10.1136/ard.2005.046300 PMid:16322081 PMCid:PMC1798210
  • Acute scrotum in Henoch-Schönlein purpura: fact or fiction? Turk J Pediatr 2012;54:194-7. PMid:22734311
  • Cassidy JT, Petty RE, Laxer RM, Lindsley CB, eds. Textbook of Pediatric Rheumatology. 5th ed. Philadelphia: WB Saunders; 2005:496-507. http://dx.doi.org/10.1016/B978-1-4160-0246-8.50029-2
  • Zhang Y, Huang X. Gastrointestinal involvement in Henoch- Schönlein purpura. Scand J Gastroenterol 2008;43:1038-43. http://dx.doi.org/10.1080/00365520802101861 PMid:18609159 et al. Gastrointestinal involvement in Henoch-Schönlein syndrome: CT findings. Am J Roentgenol 1997;168:965-8. http://dx.doi.org/10.2214/ajr.168.4.9124151 PMid:9124151
  • Paradis J. Perforation of large and small bowel in Henoch- Schonlein purpura. Int J Dermatol 1997;36:361-3. http://dx.doi.org/10.1111/j.1365-4362.1997.tb03098.x PMid:9199985
  • Heuschkel RB, Murch SH. Massive gastrointestinal hae- morrhage in isolated intestinal Henoch-Schonlein purpura with response to intravenous immunoglobulin infusion. Eur J Pediatr 2007;166:915-9. http://dx.doi.org/10.1007/s00431-006-0337-3 PMid:17120033
  • Warris A, Draaisma JM. Refractory severe intestinal vascu- litis due to Henoch-Schönlein purpura: successful treatment with plasmapheresis. Acta Paediatr 2006;95:622-3. http://dx.doi.org/10.1080/08035250500509180 PMid:16825146 treatment of gastrointestinal involvement in Henoch-Schönlein purpura with plasmapheresis. Pediatr Nephrol 2008;23:2103. http://dx.doi.org/10.1007/s00467-008-0886-y PMid:18546025
  • Schoenlein purpura: pathophysiologic mechanisms, the diag- nostic value of factor XIII, and therapeutic options. Eur J Pediatr 2007;166:1199-200. http://dx.doi.org/10.1007/s00431-007-0415-1 PMid:17333275 ment of mesenteric vasculitis caused by Henoch-Schönlein purpura with methylprednisolone pulse therapy. Clin Rheumatol 2003;22:140-2. http://dx.doi.org/10.1007/s10067-002-0676-z PMid:12740680
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makaleleri
Yazarlar

Belde Kasap Demir Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 13 Sayı: 2

Kaynak Göster

APA Kasap Demir, B. (2013). Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu. Çocuk Dergisi, 13(2), 73-76. https://doi.org/10.5222/j.child.2013.073
AMA Kasap Demir B. Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu. Çocuk Dergisi. Nisan 2013;13(2):73-76. doi:10.5222/j.child.2013.073
Chicago Kasap Demir, Belde. “Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu”. Çocuk Dergisi 13, sy. 2 (Nisan 2013): 73-76. https://doi.org/10.5222/j.child.2013.073.
EndNote Kasap Demir B (01 Nisan 2013) Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu. Çocuk Dergisi 13 2 73–76.
IEEE B. Kasap Demir, “Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu”, Çocuk Dergisi, c. 13, sy. 2, ss. 73–76, 2013, doi: 10.5222/j.child.2013.073.
ISNAD Kasap Demir, Belde. “Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu”. Çocuk Dergisi 13/2 (Nisan 2013), 73-76. https://doi.org/10.5222/j.child.2013.073.
JAMA Kasap Demir B. Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu. Çocuk Dergisi. 2013;13:73–76.
MLA Kasap Demir, Belde. “Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu”. Çocuk Dergisi, c. 13, sy. 2, 2013, ss. 73-76, doi:10.5222/j.child.2013.073.
Vancouver Kasap Demir B. Henoch-Schönlein Vaskülitinde Şiddetli Gastrointestinal Tutulum: Vaka Sunumu. Çocuk Dergisi. 2013;13(2):73-6.