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A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse

Yıl 2024, Cilt: 24 Sayı: 3, 193 - 196, 03.01.2025
https://doi.org/10.26650/jchild.2024.1464480

Öz

Acute infantile hemorrhagic edema (AIHE) is a type of leukocytoclastic vasculitis with a generally good prognosis and is observed in infants aged 4-24 months. It may be difficult to diagnose in some cases because its clinical findings are similar to those of many other diseases. Trauma and child abuse are among the differential diagnoses and should be first excluded. Although the exact cause of this disease is not known, it has been associated with infections, vaccines, and medications. Staphylococci, Streptococcus, and Adenovirus are the leading infective agents, while many other agents, such as Escherichia coli and Mycobacteria, have been suggested to be the cause of AIHE. Typically, purpuric skin lesions, edema, and fever are the presenting findings. Herein, we report the occurrence of the disease in a 6-month-old girl within a short period after vaccination.

Kaynakça

  • Snow IM. Purpura, urticaria, and angioneurotic edema of the hands and feet in a nursing baby. JAMA 1913; 61:18-9. google scholar
  • Saraclar Y, Tinaztepe K, Adalioglu G, Tuncer A. Acute hemorrhagic edema of infancy (AHEI): a variant of Henoch-Schonlein purpura or a distinct clinical entity? J Allergy Clin Immunol. 1990; 86: 473483. google scholar
  • Caksen H, Odabas D, Kosem M et al. Report of eight infants with acute infantile hemorrhagic edema and review of the literature. J Dermatol. 2002; 29:290-295. google scholar
  • Legrain V, Lejean S, Taieb A, Guillard JM, Battin J, Maleville J. Infantile acute hemorrhagic edema of the skin: study of ten cases. J Am Acad Dermatol. 1991; 24: 17-22. google scholar
  • Al Sufyani MA. Acute hemorrhagic edema of infancy: unusual scarring and review of the English language literature. Int J Dermatol. 2009; 48:617-22. google scholar
  • Krause I, Lazarov A, Rachmel A, Grunwald MM, Metzker A, Garty BZ, et al. Acute hemorrhagic edema of infancy, a benign variant of leucocytoclastic vasculitis. Acta Paediatr. 1996; 85:114-7. google scholar
  • Larreque M, Lesage B, Rossier A. Edema aguda hemorragico del lactante (EAHL) (purpura en escarapela) con edema postinfeccioso de Seidilmayer) vascularis alergica. Med Cutanea 1974; 11:165-174. google scholar
  • Ince E, Mumcu Y, Suskan E, Yalçınkaya F, Tümer N, Cin S. Infantile acute hemorrhagic edema: A variant of leukocytoclastic vasculitis. Pediatr Dermatol. 1995;12:224-227. google scholar
  • Lantner RR, Simon PR. Acute hemorrhagic edema of infancy. Pediatr Emerg Care 12: 111-112, 1996. google scholar
  • Saraçlar Y, Tınaztepe K. Infantile acute hemorrhage of the skin. J Am Acad Dermatol 24: 275-76, 1991. google scholar
  • Gonppryp, L.A., Todd, G. Acute hemorrhagic edema of childhood. Pediatr Dermatol. 1998;15:91-96. google scholar
  • Millard T, Harris A, MacDonald D. Acute infantile hemorrhagic edema. J Am Acad Dermatol 1999; 41: 837-39. google scholar
  • Karremann M, Jordan AJ, Bell N, Witsch M, Dürken M. Acute hemorrhagic edema of infancy: report of 4 cases and review of the current literature. Clin Pediatr (Phila). 2009;48(3):323-6. google scholar
  • N. Tomac, Y. Saraclar, I. Turktas, et al. Acute hemorrhagic edema of infancy: a case report. Clin Exp Dermatol. 1996;21:217-219 google scholar
  • Cunningham, B. B., Caro, W. A., Eramo, L. R. Neonatal acute hemorrhagic edema of childhood: A case report and review of the English-language literature. Pediatr Dermatol. 1996;13:39-44. google scholar Smitt JH, Vermeer MH, Faber WR. Acute hemorrhagic edema of infancy (AHEI). Clin Dermatol 2002; 20: 2-3. google scholar
  • Özdemir Ö, Avcı O, Akın İM, Büyükkayhan D. D-Dimer düzeyinin akut infantil hemorajik ödemde prognostik önemi. Güncel Pediatri. 2016;14(3):142- 6. google scholar
  • Sites LY, Woodmansee CS, Wilkin NK, Hanson JW, Skinner RB, Jr, Shimek CM. Acute hemorrhagic edema of infancy: case reports and a review of the literature. Cutis 2008;82:320-4. google scholar
  • Habif TP. Exanthems and drug eruptions. In: Habif, T. P. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 4th ed. Philadelphia, PA: Mosby; 2004:457-96. google scholar
  • Çoban M, Gündoğdu Çoban D, Pop S, Engin MMN, Özdemir Ö. Travma ile Karışabilen Bir Henoch- Schönlein Purpura Olgusu. Sakarya Med J 2023;13(2):329-33 google scholar
  • Taner, Y., Gökler B. Çocuk istismarı ve ihmali: psikiyatrik yönleri. Hacettepe Tıp Dergisi 2004; 35:82-86. google scholar
  • Arthur HG. Physical abuse of children. In: Wiener JM, ed. Textbook of child adolescent psychiatry. 2nd ed. Washington: American Psychiatric Press, 1997; 687-98. google scholar
  • Al Murayshid AI. Acute Hemorrhagic Edema with extensive truck involvement and Rhinovirus infection association. Journal of Dermatology & Dermatologic Surgery. 2017; 21(1):27-30. google scholar
  • Saray Y, Seçkin D, Sarifakioğlu E, Güleç AT, Demirhan B. Acute infantile hemorrhagic edema: measles vaccination as possible triggering factor. Acta Derm Venereol. 2002;82(6):471-2. google scholar
  • Binamer Y. Acute hemorrhagic edema of infancy after MMR vaccine. Ann Saudi Med. 2015; 35(3):254-6. google scholar
  • Nacaroğlu HT, Saygaz S, Sandal ÖS, Karkıner CŞÜ, Yıldırım HT, Can D. Acute hemorrhagic edema of infancy after vaccination: A case report. J Pediatr Inf 2014; 8, 40-3. google scholar
Yıl 2024, Cilt: 24 Sayı: 3, 193 - 196, 03.01.2025
https://doi.org/10.26650/jchild.2024.1464480

Öz

Kaynakça

  • Snow IM. Purpura, urticaria, and angioneurotic edema of the hands and feet in a nursing baby. JAMA 1913; 61:18-9. google scholar
  • Saraclar Y, Tinaztepe K, Adalioglu G, Tuncer A. Acute hemorrhagic edema of infancy (AHEI): a variant of Henoch-Schonlein purpura or a distinct clinical entity? J Allergy Clin Immunol. 1990; 86: 473483. google scholar
  • Caksen H, Odabas D, Kosem M et al. Report of eight infants with acute infantile hemorrhagic edema and review of the literature. J Dermatol. 2002; 29:290-295. google scholar
  • Legrain V, Lejean S, Taieb A, Guillard JM, Battin J, Maleville J. Infantile acute hemorrhagic edema of the skin: study of ten cases. J Am Acad Dermatol. 1991; 24: 17-22. google scholar
  • Al Sufyani MA. Acute hemorrhagic edema of infancy: unusual scarring and review of the English language literature. Int J Dermatol. 2009; 48:617-22. google scholar
  • Krause I, Lazarov A, Rachmel A, Grunwald MM, Metzker A, Garty BZ, et al. Acute hemorrhagic edema of infancy, a benign variant of leucocytoclastic vasculitis. Acta Paediatr. 1996; 85:114-7. google scholar
  • Larreque M, Lesage B, Rossier A. Edema aguda hemorragico del lactante (EAHL) (purpura en escarapela) con edema postinfeccioso de Seidilmayer) vascularis alergica. Med Cutanea 1974; 11:165-174. google scholar
  • Ince E, Mumcu Y, Suskan E, Yalçınkaya F, Tümer N, Cin S. Infantile acute hemorrhagic edema: A variant of leukocytoclastic vasculitis. Pediatr Dermatol. 1995;12:224-227. google scholar
  • Lantner RR, Simon PR. Acute hemorrhagic edema of infancy. Pediatr Emerg Care 12: 111-112, 1996. google scholar
  • Saraçlar Y, Tınaztepe K. Infantile acute hemorrhage of the skin. J Am Acad Dermatol 24: 275-76, 1991. google scholar
  • Gonppryp, L.A., Todd, G. Acute hemorrhagic edema of childhood. Pediatr Dermatol. 1998;15:91-96. google scholar
  • Millard T, Harris A, MacDonald D. Acute infantile hemorrhagic edema. J Am Acad Dermatol 1999; 41: 837-39. google scholar
  • Karremann M, Jordan AJ, Bell N, Witsch M, Dürken M. Acute hemorrhagic edema of infancy: report of 4 cases and review of the current literature. Clin Pediatr (Phila). 2009;48(3):323-6. google scholar
  • N. Tomac, Y. Saraclar, I. Turktas, et al. Acute hemorrhagic edema of infancy: a case report. Clin Exp Dermatol. 1996;21:217-219 google scholar
  • Cunningham, B. B., Caro, W. A., Eramo, L. R. Neonatal acute hemorrhagic edema of childhood: A case report and review of the English-language literature. Pediatr Dermatol. 1996;13:39-44. google scholar Smitt JH, Vermeer MH, Faber WR. Acute hemorrhagic edema of infancy (AHEI). Clin Dermatol 2002; 20: 2-3. google scholar
  • Özdemir Ö, Avcı O, Akın İM, Büyükkayhan D. D-Dimer düzeyinin akut infantil hemorajik ödemde prognostik önemi. Güncel Pediatri. 2016;14(3):142- 6. google scholar
  • Sites LY, Woodmansee CS, Wilkin NK, Hanson JW, Skinner RB, Jr, Shimek CM. Acute hemorrhagic edema of infancy: case reports and a review of the literature. Cutis 2008;82:320-4. google scholar
  • Habif TP. Exanthems and drug eruptions. In: Habif, T. P. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 4th ed. Philadelphia, PA: Mosby; 2004:457-96. google scholar
  • Çoban M, Gündoğdu Çoban D, Pop S, Engin MMN, Özdemir Ö. Travma ile Karışabilen Bir Henoch- Schönlein Purpura Olgusu. Sakarya Med J 2023;13(2):329-33 google scholar
  • Taner, Y., Gökler B. Çocuk istismarı ve ihmali: psikiyatrik yönleri. Hacettepe Tıp Dergisi 2004; 35:82-86. google scholar
  • Arthur HG. Physical abuse of children. In: Wiener JM, ed. Textbook of child adolescent psychiatry. 2nd ed. Washington: American Psychiatric Press, 1997; 687-98. google scholar
  • Al Murayshid AI. Acute Hemorrhagic Edema with extensive truck involvement and Rhinovirus infection association. Journal of Dermatology & Dermatologic Surgery. 2017; 21(1):27-30. google scholar
  • Saray Y, Seçkin D, Sarifakioğlu E, Güleç AT, Demirhan B. Acute infantile hemorrhagic edema: measles vaccination as possible triggering factor. Acta Derm Venereol. 2002;82(6):471-2. google scholar
  • Binamer Y. Acute hemorrhagic edema of infancy after MMR vaccine. Ann Saudi Med. 2015; 35(3):254-6. google scholar
  • Nacaroğlu HT, Saygaz S, Sandal ÖS, Karkıner CŞÜ, Yıldırım HT, Can D. Acute hemorrhagic edema of infancy after vaccination: A case report. J Pediatr Inf 2014; 8, 40-3. google scholar
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk İmmünolojisi ve Alerji Hastalıkları
Bölüm Olgu Sunumu
Yazarlar

Muhammet Bir 0009-0001-8945-7239

Öner Özdemir 0000-0002-5338-9561

Ümmügülsüm Dikici 0000-0002-7435-1108

Ceren Naz Yolaçık 0009-0008-5973-6449

Yayımlanma Tarihi 3 Ocak 2025
Gönderilme Tarihi 3 Nisan 2024
Kabul Tarihi 29 Mayıs 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 24 Sayı: 3

Kaynak Göster

APA Bir, M., Özdemir, Ö., Dikici, Ü., Yolaçık, C. N. (2025). A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse. Çocuk Dergisi, 24(3), 193-196. https://doi.org/10.26650/jchild.2024.1464480
AMA Bir M, Özdemir Ö, Dikici Ü, Yolaçık CN. A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse. Çocuk Dergisi. Ocak 2025;24(3):193-196. doi:10.26650/jchild.2024.1464480
Chicago Bir, Muhammet, Öner Özdemir, Ümmügülsüm Dikici, ve Ceren Naz Yolaçık. “A Case of Acute Infantile Hemorrhagic Edema Confused With Child Abuse”. Çocuk Dergisi 24, sy. 3 (Ocak 2025): 193-96. https://doi.org/10.26650/jchild.2024.1464480.
EndNote Bir M, Özdemir Ö, Dikici Ü, Yolaçık CN (01 Ocak 2025) A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse. Çocuk Dergisi 24 3 193–196.
IEEE M. Bir, Ö. Özdemir, Ü. Dikici, ve C. N. Yolaçık, “A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse”, Çocuk Dergisi, c. 24, sy. 3, ss. 193–196, 2025, doi: 10.26650/jchild.2024.1464480.
ISNAD Bir, Muhammet vd. “A Case of Acute Infantile Hemorrhagic Edema Confused With Child Abuse”. Çocuk Dergisi 24/3 (Ocak 2025), 193-196. https://doi.org/10.26650/jchild.2024.1464480.
JAMA Bir M, Özdemir Ö, Dikici Ü, Yolaçık CN. A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse. Çocuk Dergisi. 2025;24:193–196.
MLA Bir, Muhammet vd. “A Case of Acute Infantile Hemorrhagic Edema Confused With Child Abuse”. Çocuk Dergisi, c. 24, sy. 3, 2025, ss. 193-6, doi:10.26650/jchild.2024.1464480.
Vancouver Bir M, Özdemir Ö, Dikici Ü, Yolaçık CN. A Case of Acute Infantile Hemorrhagic Edema Confused with Child Abuse. Çocuk Dergisi. 2025;24(3):193-6.