Araştırma Makalesi
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Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience

Yıl 2024, Cilt: 24 Sayı: 3, 168 - 173, 03.01.2025
https://doi.org/10.26650/jchild.2024.1507342

Öz

Objective: Long-term noninvasive ventilation (NIV) support is increasingly being used by pediatricians for children with complex medical diseases. However, data on NIV support among children in Turkiye are limited.

Methods: This study included children who received long-term NIV support between July 2022 and July 2024 at a single center. Demographic and clinical characteristics and short-term clinical outcomes were retrospectively evaluated.

Results: A total of 30 patients were included. The median age at NIV initiation was 39.5 months (range: 9–108 months), and the most common underlying etiology was cardiovascular diseases (n = 9, 30%). Twenty-six patients were discharged with long-term NIV support, with a median discharge time of 5.5 days (range: 3–13 days) after NIV initiation. Of the 26 patients discharged with NIV support, four died during follow-up. Three patients, all of whom were from the cardiovascular group, no longer required respiratory support.

Conclusions: NIV can be used effectively for a wide variety of diseases in children. Understanding the current status of NIV support in our clinical setting may help us design a protocol to improve future outcomes.

Kaynakça

  • Atag E, Krivec U, Ersu R. Noninvasive ventilation for children with chronic lung disease. Front Pediatr. 2020;11(8):561639. google scholar
  • Pavone M, Verrillo E, Caldarelli V, Ullmann N, Cutrera R. Noninvasive positive pressure ventilation in children. Early Hum Dev. 2013;89(Suppl 3):S25-31. google scholar
  • MacLean JE, Fauroux B. Long-term noninvasive ventilation in children: Transition from hospital to home. Paediatr Respir Rev. 2023;(47):3-10. google scholar
  • Amaddeo A, Frapin A, Fauroux B. Long-term noninvasive ventilation in children. Lancet Respir Med. 2016;(12):999-1008. google scholar
  • Chatwin M, Bush A, Simonds AK. Outcomes of goal-directed noninvasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type I. Arch Dis Child. 2011;96(5):426-32. google scholar
  • Ishikawa Y, Miura T, Ishikawa Y, Aoyagi T, Ogata H, Hamada S et al. Duchenne muscular dystrophy: survival by cardio-respiratory interventions. Neuromuscul Disord. 2011;21(1):47-51. google scholar
  • Oskoui M, Levy G, Garland CJ, Gray JM, O’Hagen J, De Vivo DC,et al. The natural history of spinal muscular atrophy type 1. Neurology. 2007;69(20):1931-6 google scholar
  • McDougall CM, Adderley RJ, Wensley DF, Seear MD. Long-term ventilation in children: longitudinal trends and outcomes. Arch Dis Child. 2013;98(9):660-5. google scholar
  • Praud JP. Long-Term Non-invasive Ventilation in Children: Current Use, Indications, and Contraindications. Front Pediatr. 2020;5(8):584334. google scholar
  • Mayer OH, Amin R, Sawnani H, Shell R, Katz SL; RIND Study Group. Respiratory Insufficiency in Neuromuscular Disease (RIND): A Delphi Study to Establish Consensus Criteria for Define and Diagnose Hypoventilation in Pediatric Neuromuscular Disease. J Neuromuscul Dis. 2023;10(6):1075-1082. google scholar
  • Berry RB, Quan SF, Abreu AR, Bibbs ML, DelRosso L et al. The AASM Manual for Sleep Scoring and Associated Events: Rules, Terminology and Technical Specifications. American Academy of Sleep Medicine; 2020 google scholar
  • Chatwin M, Tan HL, Bush A, Rosenthal M, Simonds AK. Long-term noninvasive ventilation in children: impact on survival and transition to adult care. PLoS One. 2015;10(5):e0125839. google scholar
  • Castro-Codesal ML, Dehaan K, Featherstone R, Bedi PK, Martinez Carrasco C, Katz SL, et al. . Long-term noninvasive ventilation therapies for children: A scoping review. Sleep Med Rev. 2018;37:148-158. google scholar
  • Ikeda A, Tsuji M, Goto T, Iai M. Long-term home noninvasive positive pressure ventilation in children: Results from a single center in Japan. Brain Dev. 2018;40(7):558-565. google scholar
  • Racca F, Berta G, Sequi M, Bignamini E, Capello E, Cutrera R, et al.; LTV Pediatric Italian Network. Long-term home ventilation of children in Italy: a national survey. Pediatr Pulmonol. 2011;46(6):566-72. google scholar
  • Amin R, Sayal P, Syed F, Chaves A, Moraes TJ, MacLusky I. Pediatric long-term home mechanical ventilation: 20 years of follow-up at one Canadian center. Pediatr Pulmonol. 2014;49(8):816-24. google scholar
  • Oktem S, Cakir E, Uyan ZS, Karadag B, Hamutcu RE, Kiyan G et al. Diaphragmatic paralysis after pediatric heart surgery: usefulness of non-invasive ventilation. Int J Pediatr Otorhinolaryngol. 2010;74(4):430-1. google scholar
  • Kovacikova L, Dobos D, Zahorec M. Noninvasive positive pressure ventilation for bilateral diaphragm paralysis after pediatric cardiac surgery. Interact Cardiovasc Thorac Surg. 2009;8(1):171-2. google scholar
  • Fernândez Lafever S, Toledo B, Leiva M, Padron M, Balseiro M, Carrillo A, Lopez-Herce J. Non-invasive mechanical ventilation after heart surgery in children. BMC Pulm Med. 2016;16(1):167. google scholar
Yıl 2024, Cilt: 24 Sayı: 3, 168 - 173, 03.01.2025
https://doi.org/10.26650/jchild.2024.1507342

Öz

Kaynakça

  • Atag E, Krivec U, Ersu R. Noninvasive ventilation for children with chronic lung disease. Front Pediatr. 2020;11(8):561639. google scholar
  • Pavone M, Verrillo E, Caldarelli V, Ullmann N, Cutrera R. Noninvasive positive pressure ventilation in children. Early Hum Dev. 2013;89(Suppl 3):S25-31. google scholar
  • MacLean JE, Fauroux B. Long-term noninvasive ventilation in children: Transition from hospital to home. Paediatr Respir Rev. 2023;(47):3-10. google scholar
  • Amaddeo A, Frapin A, Fauroux B. Long-term noninvasive ventilation in children. Lancet Respir Med. 2016;(12):999-1008. google scholar
  • Chatwin M, Bush A, Simonds AK. Outcomes of goal-directed noninvasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type I. Arch Dis Child. 2011;96(5):426-32. google scholar
  • Ishikawa Y, Miura T, Ishikawa Y, Aoyagi T, Ogata H, Hamada S et al. Duchenne muscular dystrophy: survival by cardio-respiratory interventions. Neuromuscul Disord. 2011;21(1):47-51. google scholar
  • Oskoui M, Levy G, Garland CJ, Gray JM, O’Hagen J, De Vivo DC,et al. The natural history of spinal muscular atrophy type 1. Neurology. 2007;69(20):1931-6 google scholar
  • McDougall CM, Adderley RJ, Wensley DF, Seear MD. Long-term ventilation in children: longitudinal trends and outcomes. Arch Dis Child. 2013;98(9):660-5. google scholar
  • Praud JP. Long-Term Non-invasive Ventilation in Children: Current Use, Indications, and Contraindications. Front Pediatr. 2020;5(8):584334. google scholar
  • Mayer OH, Amin R, Sawnani H, Shell R, Katz SL; RIND Study Group. Respiratory Insufficiency in Neuromuscular Disease (RIND): A Delphi Study to Establish Consensus Criteria for Define and Diagnose Hypoventilation in Pediatric Neuromuscular Disease. J Neuromuscul Dis. 2023;10(6):1075-1082. google scholar
  • Berry RB, Quan SF, Abreu AR, Bibbs ML, DelRosso L et al. The AASM Manual for Sleep Scoring and Associated Events: Rules, Terminology and Technical Specifications. American Academy of Sleep Medicine; 2020 google scholar
  • Chatwin M, Tan HL, Bush A, Rosenthal M, Simonds AK. Long-term noninvasive ventilation in children: impact on survival and transition to adult care. PLoS One. 2015;10(5):e0125839. google scholar
  • Castro-Codesal ML, Dehaan K, Featherstone R, Bedi PK, Martinez Carrasco C, Katz SL, et al. . Long-term noninvasive ventilation therapies for children: A scoping review. Sleep Med Rev. 2018;37:148-158. google scholar
  • Ikeda A, Tsuji M, Goto T, Iai M. Long-term home noninvasive positive pressure ventilation in children: Results from a single center in Japan. Brain Dev. 2018;40(7):558-565. google scholar
  • Racca F, Berta G, Sequi M, Bignamini E, Capello E, Cutrera R, et al.; LTV Pediatric Italian Network. Long-term home ventilation of children in Italy: a national survey. Pediatr Pulmonol. 2011;46(6):566-72. google scholar
  • Amin R, Sayal P, Syed F, Chaves A, Moraes TJ, MacLusky I. Pediatric long-term home mechanical ventilation: 20 years of follow-up at one Canadian center. Pediatr Pulmonol. 2014;49(8):816-24. google scholar
  • Oktem S, Cakir E, Uyan ZS, Karadag B, Hamutcu RE, Kiyan G et al. Diaphragmatic paralysis after pediatric heart surgery: usefulness of non-invasive ventilation. Int J Pediatr Otorhinolaryngol. 2010;74(4):430-1. google scholar
  • Kovacikova L, Dobos D, Zahorec M. Noninvasive positive pressure ventilation for bilateral diaphragm paralysis after pediatric cardiac surgery. Interact Cardiovasc Thorac Surg. 2009;8(1):171-2. google scholar
  • Fernândez Lafever S, Toledo B, Leiva M, Padron M, Balseiro M, Carrillo A, Lopez-Herce J. Non-invasive mechanical ventilation after heart surgery in children. BMC Pulm Med. 2016;16(1):167. google scholar
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Göğüs Hastalıkları
Bölüm Araştırma Makaleleri
Yazarlar

Cansu Yılmaz Yegit 0000-0001-8239-4776

Esin Aldemir 0000-0001-6141-7940

Erkut Ozturk 0000-0002-1762-3269

Mehmet Arda Kılınç 0000-0001-9121-2188

Mehmet Gümüştaş Bu kişi benim 0000-0002-4846-5398

Hasan Onal 0000-0001-9676-7086

Alican Hatemi Bu kişi benim 0000-0002-6202-3262

Merih Çetinkaya Bu kişi benim 0000-0002-7344-8637

Yayımlanma Tarihi 3 Ocak 2025
Gönderilme Tarihi 2 Temmuz 2024
Kabul Tarihi 31 Ekim 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 24 Sayı: 3

Kaynak Göster

APA Yılmaz Yegit, C., Aldemir, E., Ozturk, E., Kılınç, M. A., vd. (2025). Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience. Çocuk Dergisi, 24(3), 168-173. https://doi.org/10.26650/jchild.2024.1507342
AMA Yılmaz Yegit C, Aldemir E, Ozturk E, Kılınç MA, Gümüştaş M, Onal H, Hatemi A, Çetinkaya M. Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience. Çocuk Dergisi. Ocak 2025;24(3):168-173. doi:10.26650/jchild.2024.1507342
Chicago Yılmaz Yegit, Cansu, Esin Aldemir, Erkut Ozturk, Mehmet Arda Kılınç, Mehmet Gümüştaş, Hasan Onal, Alican Hatemi, ve Merih Çetinkaya. “Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience”. Çocuk Dergisi 24, sy. 3 (Ocak 2025): 168-73. https://doi.org/10.26650/jchild.2024.1507342.
EndNote Yılmaz Yegit C, Aldemir E, Ozturk E, Kılınç MA, Gümüştaş M, Onal H, Hatemi A, Çetinkaya M (01 Ocak 2025) Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience. Çocuk Dergisi 24 3 168–173.
IEEE C. Yılmaz Yegit, E. Aldemir, E. Ozturk, M. A. Kılınç, M. Gümüştaş, H. Onal, A. Hatemi, ve M. Çetinkaya, “Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience”, Çocuk Dergisi, c. 24, sy. 3, ss. 168–173, 2025, doi: 10.26650/jchild.2024.1507342.
ISNAD Yılmaz Yegit, Cansu vd. “Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience”. Çocuk Dergisi 24/3 (Ocak 2025), 168-173. https://doi.org/10.26650/jchild.2024.1507342.
JAMA Yılmaz Yegit C, Aldemir E, Ozturk E, Kılınç MA, Gümüştaş M, Onal H, Hatemi A, Çetinkaya M. Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience. Çocuk Dergisi. 2025;24:168–173.
MLA Yılmaz Yegit, Cansu vd. “Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience”. Çocuk Dergisi, c. 24, sy. 3, 2025, ss. 168-73, doi:10.26650/jchild.2024.1507342.
Vancouver Yılmaz Yegit C, Aldemir E, Ozturk E, Kılınç MA, Gümüştaş M, Onal H, Hatemi A, Çetinkaya M. Clinical Characteristics of Patients Initiated on Long-Term Noninvasive Ventilation Support: A Single-Center Experience. Çocuk Dergisi. 2025;24(3):168-73.