Cerrahi ve radyoterapi ile tedavi edilen erken evre jinekolojik kanserli geriatrik hastalarda onkolojik sonuçlar

Öz

ÖZ Amaç: Erken evre jinekolojik kanserli geriatrik hasta grubunda cerrahi ve adjuvan radyoterapi ile elde edilen onkolojik sonuçların değerlendirilmesidir. Metod: 65 yaş ve üzeri, erken evre jinekolojik kanser nedeni ile opere edilmiş ve adjuvan radyoterapi uygulanmış 31 hasta çalışmaya dahil edilmiştir. Tüm hastalar genel özellikler, uygulanan local ve sistemik tedaviler, ve onkolojik sonuçlar açısından değerlendirimiştir. Bulgular: Hastaların tanısına bakıldığında 80,6% sının endometrıum ca,19,4%ünün serviks ca olduğu gözlenmiştir. The median age of the patients was 69 (range, 65-86). All patients underwent TAH+BSO. Hastaların tamamına eksternal pelvik RT ygulanmıştı. Intrakaviter vaginal braki terapi hastaların 90,3 %’sine uygulanmıştı. Hastaların 3,2% sinde lokal rekürrens ve yine 3,2% sinde uzak metastaz gözlenmişti. The five-year DFS and OS rates were 93% and 80%, respectively Sonuç: Geriatrik hasta grubunda tedavi planlaması prognostik faktörler, yaş grubu ve komorbidite ye göre uygun olarak şekillendirilmelidir. Seçili hasta grubunda multimodalite tedaviler ile gayet iyi onkolojik sonuçlar elde edilebilmektedir.

Anahtar Kelimeler

• Jinekolojik kanser
• Radyoterapi
• Geriatri

Oncological outcomes in geriatric patients with early stage gynecological cancer who underwent surgery and radiotherapy

Öz

ABSTRACT Background: Evaluation of oncological results obtained with surgery and adjuvant radiotherapy in geriatric patient group with early stage gynecological cancer. Methods: 31 patients aged 65 years and older who were operated for early stage gynecological cancer and had adjuvant radiotherapy were included in the study. All patients were evaluated in terms of general characteristics, local and systemic treatments, and oncological outcomes. Results: Percentages of patients diagnosed with endometrium ca and cervix ca are 80.6% and 19.4%, respectively. The median age of the patients was 69 (range, 65-86). All patients underwent total abdominal hysterectomy and bilateral salpingo oophorectomy, followed by adjuvant pelvic radiotherapy. Intracavitary vaginal brachytherapy was applied to 90.3% of the patients. At a median follow-up of 69 months, 3.2% of patients had local recurrence and 3.2% had distant metastases. The five-year DFS and OS rates were 93% and 80%, respectively Conclusions: Treatment planning in geriatric patient group should be shaped according to prognostic factors, age group and comorbidity. Remarkable oncological results can be obtained with multimodality treatments in the selected patient group.

Anahtar Kelimeler

• Gynecologic cancer
• Radiotherapy
• Geriatric patients

Kaynakça

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